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Maxwell Gyamfi

TitleResearch Scientist, JLC-BBRI
InstitutionNorth Carolina Central University
DepartmentL+JLC-BBRI
Address700 George Street
Durham NC 27707
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kathuria I, Prasad A, Sharma BK, Aithabathula RV, Ofosu-Boateng M, Gyamfi MA, Jiang J, Park F, Singh UP, Singla B. Nidogen 2 Overexpression Promotes Hepatosteatosis and Atherosclerosis. Int J Mol Sci. 2024 Nov 28; 25(23). PMID: 39684493.
      Citations:    Fields:    Translation:HumansAnimals
    2. Choi S, Ofosu-Boateng M, Kim S, Nnamani DO, Mah'moud M, Neequaye P, Gebreyesus LH, Twum E, Gonzalez FJ, Yue Cui J, Gyamfi MA. Molecular targets of PXR-dependent ethanol-induced hepatotoxicity in female mice. Biochem Pharmacol. 2024 10; 228:116416. PMID: 38986717.
      Citations:    Fields:    Translation:Animals
    3. Gebreyesus LH, Choi S, Neequaye P, Mahmoud M, Mahmoud M, Ofosu-Boateng M, Twum E, Nnamani DO, Wang L, Yadak N, Ghosh S, Gonzalez FJ, Gyamfi MA. Pregnane X receptor knockout mitigates weight gain and hepatic metabolic dysregulation in female C57BL/6?J mice on a long-term high-fat diet. Biomed Pharmacother. 2024 Apr; 173:116341. PMID: 38428309.
      Citations: 1     Fields:    Translation:Animals
    4. Ofosu-Boateng M, Shaik F, Choi S, Ekuban FA, Gebreyesus LH, Twum E, Nnamani DO, Yeyeodu ST, Yadak N, Collier DM, Gyamfi MA. High-fat diet induced obesity promotes inflammation, oxidative stress, and hepatotoxicity in female FVB/N mice. Biofactors. 2024 May-Jun; 50(3):572-591. PMID: 38183321.
      Citations: 1     Fields:    Translation:Animals
    5. Singla B, Aithbathula RV, Pervaiz N, Kathuria I, Swanson M, Ekuban FA, Ahn W, Park F, Gyamfi M, Cherian-Shaw M, Singh UP, Kumar S. CD47 Activation by Thrombospondin-1 in Lymphatic Endothelial Cells Suppresses Lymphangiogenesis and Promotes Atherosclerosis. Arterioscler Thromb Vasc Biol. 2023 07; 43(7):1234-1250. PMID: 37259865.
      Citations: 3     Fields:    Translation:AnimalsCells
    6. Niture S, Gadi S, Qi Q, Gyamfi MA, Varghese RS, Rios-Colon L, Chimeh U, Ressom HW, Kumar D. MicroRNA-483-5p Inhibits Hepatocellular Carcinoma Cell Proliferation, Cell Steatosis, and Fibrosis by Targeting PPARa and TIMP2. Cancers (Basel). 2023 Mar 10; 15(6). PMID: 36980601.
      Citations:    
    7. Kim S, Choi S, Dutta M, Asubonteng JO, Polunas M, Goedken M, Gonzalez FJ, Cui JY, Gyamfi MA. Pregnane X receptor exacerbates nonalcoholic fatty liver disease accompanied by obesity- and inflammation-prone gut microbiome signature. Biochem Pharmacol. 2021 11; 193:114698. PMID: 34303710.
      Citations: 17     Fields:    Translation:Animals
    8. Niture S, Gyamfi MA, Lin M, Chimeh U, Dong X, Zheng W, Moore J, Kumar D. TNFAIP8 regulates autophagy, cell steatosis, and promotes hepatocellular carcinoma cell proliferation. Cell Death Dis. 2020 03 09; 11(3):178. PMID: 32152268.
      Citations: 20     Fields:    Translation:HumansAnimals
    9. Niture S, Gyamfi MA, Kedir H, Arthur E, Ressom H, Deep G, Kumar D. Serotonin induced hepatic steatosis is associated with modulation of autophagy and notch signaling pathway. Cell Commun Signal. 2018 11 08; 16(1):78. PMID: 30409162.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    10. Choi S, Gyamfi AA, Neequaye P, Addo S, Gonzalez FJ, Gyamfi MA. Role of the pregnane X receptor in binge ethanol-induced steatosis and hepatotoxicity. J Pharmacol Exp Ther. 2018 04 01; 365(1):165-178. PMID: 29431616.
      Citations: 9     Fields:    
    11. Choi S, Neequaye P, French SW, Gonzalez FJ, Gyamfi MA. Pregnane X receptor promotes ethanol-induced hepatosteatosis in mice. J Biol Chem. 2018 01 05; 293(1):1-17. PMID: 29123032.
      Citations: 15     Fields:    Translation:AnimalsCells
    12. Spruiell K, Gyamfi AA, Yeyeodu ST, Richardson RM, Gonzalez FJ, Gyamfi MA. Pregnane X Receptor-Humanized Mice Recapitulate Gender Differences in Ethanol Metabolism but Not Hepatotoxicity. J Pharmacol Exp Ther. 2015 Sep; 354(3):459-70. PMID: 26159875.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    13. Spruiell K, Jones DZ, Cullen JM, Awumey EM, Gonzalez FJ, Gyamfi MA. Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female mice. Biochem Pharmacol. 2014 Jun 01; 89(3):399-412. PMID: 24721462.
      Citations: 21     Fields:    Translation:HumansAnimals
    14. Spruiell K, Richardson RM, Cullen JM, Awumey EM, Gonzalez FJ, Gyamfi MA. Role of pregnane X receptor in obesity and glucose homeostasis in male mice. J Biol Chem. 2014 Feb 07; 289(6):3244-61. PMID: 24362030.
      Citations: 42     Fields:    Translation:HumansAnimals
    15. Eelbo T, Wasniowska M, Thakur P, Gyamfi M, Sachs B, Wehling TO, Forti S, Starke U, Tieg C, Lichtenstein AI, Wiesendanger R. Adatoms and clusters of 3d transition metals on graphene: electronic and magnetic configurations. Phys Rev Lett. 2013 Mar 29; 110(13):136804. PMID: 23581356.
      Citations: 8     Fields:    
    16. Gyamfi MA, Wan YJ. Pathogenesis of alcoholic liver disease: the role of nuclear receptors. Exp Biol Med (Maywood). 2010 May; 235(5):547-60. PMID: 20463294.
      Citations: 34     Fields:    Translation:HumansAnimals
    17. Meckler S, Gyamfi M, Pietzsch O, Wiesendanger R. A low-temperature spin-polarized scanning tunneling microscope operating in a fully rotatable magnetic field. Rev Sci Instrum. 2009 Feb; 80(2):023708. PMID: 19256654.
      Citations: 2     Fields:    
    18. Gyamfi MA, Wan YJ. Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis. J Biol Chem. 2009 Apr 03; 284(14):9321-30. PMID: 19176532.
      Citations: 12     Fields:    Translation:AnimalsCells
    19. Gyamfi MA, Tanaka Y, He L, Klaassen CD, Wan YJ. Hepatic effects of a methionine-choline-deficient diet in hepatocyte RXRalpha-null mice. Toxicol Appl Pharmacol. 2009 Jan 15; 234(2):166-78. PMID: 18952117.
      Citations: 13     Fields:    Translation:AnimalsCells
    20. Wortham M, He L, Gyamfi M, Copple BL, Wan YJ. The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet. Dig Dis Sci. 2008 Oct; 53(10):2761-74. PMID: 18299981.
      Citations: 30     Fields:    Translation:Animals
    21. Tanaka Y, Aleksunes LM, Yeager RL, Gyamfi MA, Esterly N, Guo GL, Klaassen CD. NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet. J Pharmacol Exp Ther. 2008 May; 325(2):655-64. PMID: 18281592.
      Citations: 125     Fields:    Translation:Animals
    22. Gyamfi MA, He L, French SW, Damjanov I, Wan YJ. Hepatocyte retinoid X receptor alpha-dependent regulation of lipid homeostasis and inflammatory cytokine expression contributes to alcohol-induced liver injury. J Pharmacol Exp Ther. 2008 Feb; 324(2):443-53. PMID: 17975011.
      Citations: 34     Fields:    Translation:AnimalsCells
    23. Gyamfi MA, Damjanov I, French S, Wan YJ. The pathogenesis of ethanol versus methionine and choline deficient diet-induced liver injury. Biochem Pharmacol. 2008 Feb 15; 75(4):981-95. PMID: 18036573.
      Citations: 24     Fields:    Translation:Animals
    24. Gyamfi MA, Kocsis MG, He L, Dai G, Mendy AJ, Wan YJ. The role of retinoid X receptor alpha in regulating alcohol metabolism. J Pharmacol Exp Ther. 2006 Oct; 319(1):360-8. PMID: 16829625.
      Citations: 24     Fields:    Translation:Animals
    25. Gyamfi MA, Wan YJ. The effect of ethanol, ethanol metabolizing enzyme inhibitors, and Vitamin E on regulating glutathione, glutathione S-transferase, and S-adenosylmethionine in mouse primary hepatocyte. Hepatol Res. 2006 May; 35(1):53-61. PMID: 16540368.
      Citations:    
    26. Dai G, Chou N, He L, Gyamfi MA, Mendy AJ, Slitt AL, Klaassen CD, Wan YJ. Retinoid X receptor alpha Regulates the expression of glutathione s-transferase genes and modulates acetaminophen-glutathione conjugation in mouse liver. Mol Pharmacol. 2005 Dec; 68(6):1590-6. PMID: 16157696.
      Citations: 17     Fields:    Translation:Animals
    27. Gyamfi MA, Fujieda M, Kiyotani K, Yamazaki H, Kamataki T. High prevalence of cytochrome P450 2A6*1A alleles in a black African population of Ghana. Eur J Clin Pharmacol. 2005 Feb; 60(12):855-7. PMID: 15660270.
      Citations: 11     Fields:    Translation:Humans
    28. Gyamfi MA, Ohtani II, Shinno E, Aniya Y. Inhibition of glutathione S-transferases by thonningianin A, isolated from the African medicinal herb, Thonningia sanguinea, in vitro. Food Chem Toxicol. 2004 Sep; 42(9):1401-8. PMID: 15234070.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    29. Fujieda M, Yamazaki H, Saito T, Kiyotani K, Gyamfi MA, Sakurai M, Dosaka-Akita H, Sawamura Y, Yokota J, Kunitoh H, Kamataki T. Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers. Carcinogenesis. 2004 Dec; 25(12):2451-8. PMID: 15308589.
      Citations: 61     Fields:    Translation:Humans
    30. Gyamfi MA, Tanaka T, Aniya Y. Selective suppression of cytochrome P450 gene expression by the medicinal herb, Thonningia sanguinea in rat liver. Life Sci. 2004 Feb 20; 74(14):1723-37. PMID: 14741731.
      Citations: 4     Fields:    Translation:AnimalsCells
    31. Gyamfi MA, Aniya Y. Antioxidant properties of Thonningianin A, isolated from the African medicinal herb, Thonningia sanguinea. Biochem Pharmacol. 2002 May 01; 63(9):1725-37. PMID: 12007576.
      Citations: 10     Fields:    Translation:AnimalsCells
    32. Gyamfi MA, Hokama N, Oppong-Boachie K, Aniya Y. Inhibitory effects of the medicinal herb, Thonningia sanguinea, on liver drug metabolizing enzymes of rats. Hum Exp Toxicol. 2000 Nov; 19(11):623-31. PMID: 11211240.
      Citations: 7     Fields:    Translation:AnimalsCells
    33. Ohtani II, Gotoh N, Tanaka J, Higa T, Gyamfi MA, Aniya Y. Thonningianins A and B, new antioxidants from the African medicinal herb Thonningia sanguinea. J Nat Prod. 2000 May; 63(5):676-9. PMID: 10843586.
      Citations: 7     Fields:    Translation:Animals
    34. Aniya Y, Shimabukuro M, Shimoji M, Kohatsu M, Gyamfi MA, Miyagi C, Kunii D, Takayama F, Egashira T. Antioxidant and hepatoprotective actions of the medicinal herb Artemisia campestris from the Okinawa Islands. Biol Pharm Bull. 2000 Mar; 23(3):309-12. PMID: 10726884.
      Citations: 10     Fields:    Translation:Animals
    35. Gyamfi MA, Yonamine M, Aniya Y. Free-radical scavenging action of medicinal herbs from Ghana: Thonningia sanguinea on experimentally-induced liver injuries. Gen Pharmacol. 1999 Jun; 32(6):661-7. PMID: 10401991.
      Citations: 126     Fields:    Translation:AnimalsCells
    36. Gyamfi MA, Aniya Y. Medicinal herb, Thonningia sanguinea protects against aflatoxin B1 acute hepatotoxicity in Fischer 344 rats. Hum Exp Toxicol. 1998 Aug; 17(8):418-23. PMID: 9756133.
      Citations: 6     Fields:    Translation:Animals
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