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Weifan Zheng

TitleAssociate Professor
Faculty RankAssociate Professor
InstitutionNorth Carolina Central University
AddressBiomanufacturing Research Institute and Technology Enterprise
Durham NC 27707
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    SC3GM086265     (ZHENG, WEIFAN)Jan 1, 2009 - Dec 31, 2013
    NIH
    Integrated Cheminformatics Resource for Orphan Neurodegenerative Diseases
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Abu Rabe D, Chdid L, Lamson DR, Laudeman CP, Tarpley M, Elsayed N, Smith GR, Zheng W, Dixon MS, Williams KP. Identification of Novel GANT61 Analogs with Activity in Hedgehog Functional Assays and GLI1-Dependent Cancer Cells. Molecules. 2024 Jun 28; 29(13). PMID: 38999049.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Ji X, Williams KP, Zheng W. Applying a Gene Reversal Rate Computational Methodology to Identify Drugs for a Rare Cancer: Inflammatory Breast Cancer. Cancer Inform. 2023; 22:11769351231202588. PMID: 37846218.
      Citations:    
    3. Dong X, Zheng W. Cheminformatics Modeling of Gene Silencing for Both Natural and Chemically Modified siRNAs. Molecules. 2022 Sep 28; 27(19). PMID: 36234948.
      Citations:    Fields:    
    4. Ji X, Jin C, Dong X, Dixon MS, Williams KP, Zheng W. Literature-Wide Association Studies (LWAS) for a Rare Disease: Drug Repurposing for Inflammatory Breast Cancer. Molecules. 2020 Aug 28; 25(17). PMID: 32872166.
      Citations: 4     Fields:    Translation:Humans
    5. Niture S, Gyamfi MA, Lin M, Chimeh U, Dong X, Zheng W, Moore J, Kumar D. TNFAIP8 regulates autophagy, cell steatosis, and promotes hepatocellular carcinoma cell proliferation. Cell Death Dis. 2020 03 09; 11(3):178. PMID: 32152268.
      Citations: 18     Fields:    Translation:HumansAnimals
    6. Niture S, Dong X, Arthur E, Chimeh U, Niture SS, Zheng W, Kumar D. Oncogenic Role of Tumor Necrosis Factor a-Induced Protein 8 (TNFAIP8). Cells. 2018 12 24; 8(1). PMID: 30586922.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    7. Law CJ, Ashcroft HA, Zheng W, Sexton JZ. Assay development and multivariate scoring for high-content discovery of chemoprotectants of endoplasmic-reticulum-stress-mediated amylin-induced cytotoxicity in pancreatic beta cells. Assay Drug Dev Technol. 2014 Sep; 12(7):375-84. PMID: 25181410.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    8. Dong X, Ebalunode JO, Yang SY, Zheng W. Receptor-based pharmacophore and pharmacophore key descriptors for virtual screening and QSAR modeling. Curr Comput Aided Drug Des. 2011 Sep 01; 7(3):181-9. PMID: 21726192.
      Citations: 6     Fields:    Translation:HumansAnimals
    9. Dong X, Hilliard SG, Zheng W. Structure-based quantitative structure--activity relationship modeling of estrogen receptor ?-ligands. Future Med Chem. 2011 Jun; 3(8):933-45. PMID: 21707397.
      Citations: 1     Fields:    Translation:HumansCells
    10. Ebalunode JO, Jagun C, Zheng W. Informatics approach to the rational design of siRNA libraries. Methods Mol Biol. 2011; 672:341-58. PMID: 20838976.
      Citations: 3     Fields:    
    11. Ebalunode JO, Zheng W. Cheminformatics Approach to Gene Silencing: Z Descriptors of Nucleotides and SVM Regression Afford Predictive Models for siRNA Potency. Mol Inform. 2010 Dec 17; 29(12):871-81. PMID: 27464351.
      Citations: 1     Fields:    
    12. Dong X, Ebalunode JO, Cho SJ, Zheng W. A novel structure-based multimode QSAR method affords predictive models for phosphodiesterase inhibitors. J Chem Inf Model. 2010 Feb 22; 50(2):240-50. PMID: 20095527.
      Citations:    Fields:    
    13. Ebalunode JO, Zheng W. Molecular shape technologies in drug discovery: methods and applications. Curr Top Med Chem. 2010; 10(6):669-79. PMID: 20337591.
      Citations: 5     Fields:    
    14. Adekoya A, Dong X, Ebalunode J, Zheng W. Development of improved models for phosphodiesterase-4 inhibitors with a multi-conformational structure-based QSAR method. Curr Chem Genomics. 2009 Dec 31; 3:54-61. PMID: 20161837.
      Citations:    
    15. Ebalunode JO, Zheng W. Unconventional 2D shape similarity method affords comparable enrichment as a 3D shape method in virtual screening experiments. J Chem Inf Model. 2009 Jun; 49(6):1313-20. PMID: 19480404.
      Citations: 3     Fields:    Translation:HumansCells
    16. Ebalunode JO, Dong X, Ouyang Z, Liang J, Eckenhoff RG, Zheng W. Structure-based shape pharmacophore modeling for the discovery of novel anesthetic compounds. Bioorg Med Chem. 2009 Jul 15; 17(14):5133-8. PMID: 19520579.
      Citations: 2     Fields:    Translation:AnimalsCells
    17. Ebalunode JO, Ouyang Z, Liang J, Zheng W. Novel approach to structure-based pharmacophore search using computational geometry and shape matching techniques. J Chem Inf Model. 2008 Apr; 48(4):889-901. PMID: 18396858.
      Citations: 15     Fields:    Translation:Cells
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