Drug Discovery

"Drug Discovery" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The process of finding chemicals for potential therapeutic use.

Descriptor ID	D055808
MeSH Number(s)	E05.295 H01.158.703.007.675 H01.181.466.675
Concept/Terms	Drug Discovery Drug Discovery Discovery, Drug Drug Prospecting Drug Prospecting Prospecting, Drug

Below are MeSH descriptors whose meaning is more general than "Drug Discovery".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Drug Discovery [E05.295]
Natural Sciences [H]
Natural Science Disciplines [H01]
Biological Science Disciplines [H01.158]
Pharmacology [H01.158.703]
Chemistry, Pharmaceutical [H01.158.703.007]
Drug Discovery [H01.158.703.007.675]
Chemistry [H01.181]
Chemistry, Pharmaceutical [H01.181.466]
Drug Discovery [H01.181.466.675]

Below are MeSH descriptors whose meaning is related to "Drug Discovery".

Below are MeSH descriptors whose meaning is more specific than "Drug Discovery".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Drug Discovery" by people in this website by year, and whether "Drug Discovery" was a major or minor topic of these publications.

Bar chart showing 74 publications over 16 distinct years, with a maximum of 11 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2009	1	3	4
2010	3	2	5
2011	3	2	5
2012	0	3	3
2013	5	1	6
2014	3	3	6
2015	2	4	6
2016	2	5	7
2017	4	0	4
2018	6	5	11
2019	2	0	2
2020	3	3	6
2021	1	2	3
2022	0	3	3
2023	0	2	2
2024	1	0	1

Below are the most recent publications written about "Drug Discovery" by people in Profiles.

Liang Z, Candib A, Soriano-Castell D, Fischer W, Finley K, Maher P. Fragment-based drug discovery and biological evaluation of novel cannabinol-based inhibitors of oxytosis/ferroptosis for neurological disorders. Redox Biol. 2024 Jun; 72:103138.

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Coy-Barrera E, Ogungbe IV, Schmidt TJ. Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Therapeutics. Molecules. 2023 Apr 25; 28(9).

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Slika H, Mansour H, Nasser SA, Shaito A, Kobeissy F, Orekhov AN, Pintus G, Eid AH. Epac as a tractable therapeutic target. Eur J Pharmacol. 2023 Apr 15; 945:175645.

View in: PubMed
Metibemu DS, Ogungbe IV. Carotenoids in Drug Discovery and Medicine: Pathways and Molecular Targets Implicated in Human Diseases. Molecules. 2022 Sep 15; 27(18).

View in: PubMed
Togre NS, Vargas AM, Bhargavi G, Mallakuntla MK, Tiwari S. Fragment-Based Drug Discovery against Mycobacteria: The Success and Challenges. Int J Mol Sci. 2022 Sep 14; 23(18).

View in: PubMed
Khomtchouk BB, Lee YS, Khan ML, Sun P, Mero D, Davidson MH. Targeting the cytoskeleton and extracellular matrix in cardiovascular disease drug discovery. Expert Opin Drug Discov. 2022 05; 17(5):443-460.

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Rose M, Cardon T, Aboulouard S, Hajjaji N, Kobeissy F, Duhamel M, Fournier I, Salzet M. Surfaceome Proteomic of Glioblastoma Revealed Potential Targets for Immunotherapy. Front Immunol. 2021; 12:746168.

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Gangapuram M, Mazzio EA, Redda KK, Soliman KFA. Transcriptome Profile Analysis of Triple-Negative Breast Cancer Cells in Response to a Novel Cytostatic Tetrahydroisoquinoline Compared to Paclitaxel. Int J Mol Sci. 2021 Jul 19; 22(14).

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Li X, Gera L, Zhang S, Chen Y, Lou L, Wilson LM, Xie ZR, Sautto G, Liu D, Danaher A, Mamouni K, Yang Y, Du Y, Fu H, Kucuk O, Osunkoya AO, Zhou J, Wu D. Pharmacological inhibition of noncanonical EED-EZH2 signaling overcomes chemoresistance in prostate cancer. Theranostics. 2021; 11(14):6873-6890.

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Shao Y, Zhang QC. Targeting RNA structures in diseases with small molecules. Essays Biochem. 2020 12 07; 64(6):955-966.

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