Interferon Regulatory Factor-3
"Interferon Regulatory Factor-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
| Descriptor ID |
D050838
|
| MeSH Number(s) |
D12.644.360.024.302.374 D12.776.157.057.050.374 D12.776.260.504.374 D12.776.476.024.385.374 D12.776.744.562 D12.776.930.332.374
|
| Concept/Terms |
Interferon Regulatory Factor-3- Interferon Regulatory Factor-3
- Interferon Regulatory Factor 3
- IRF-3 Transcription Factor
- IRF 3 Transcription Factor
- Transcription Factor, IRF-3
- IFN-Regulatory Factor 3
- IFN Regulatory Factor 3
|
Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-3".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-3".
This graph shows the total number of publications written about "Interferon Regulatory Factor-3" by people in this website by year, and whether "Interferon Regulatory Factor-3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon Regulatory Factor-3" by people in Profiles.
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Rogers EN, Jones DZ, Kidd NC, Yeyeodu S, Brock G, Ragin C, Jackson M, McFarlane-Anderson N, Tulloch-Reid M, Sean Kimbro K, Kidd LR. Toll-like receptor-associated sequence variants and prostate cancer risk among men of African descent. Genes Immun. 2013 Sep; 14(6):347-55.
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Bigham AW, Buckingham KJ, Husain S, Emond MJ, Bofferding KM, Gildersleeve H, Rutherford A, Astakhova NM, Perelygin AA, Busch MP, Murray KO, Sejvar JJ, Green S, Kriesel J, Brinton MA, Bamshad M. Host genetic risk factors for West Nile virus infection and disease progression. PLoS One. 2011; 6(9):e24745.
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Dhanushkodi NR, Mohankumar V, Raju R. Sindbis virus induced phosphorylation of IRF3 in human embryonic kidney cells is not dependent on mTOR. Innate Immun. 2012 Apr; 18(2):325-32.