"Stathmin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.
| Descriptor ID |
D050777
|
| MeSH Number(s) |
D12.776.220.600.450.480 D12.776.624.664.700.957 D12.776.744.772
|
| Concept/Terms |
Stathmin- Stathmin
- Leukemia-Associated Phosphoprotein p18
- Leukemia Associated Phosphoprotein p18
- p18, Leukemia-Associated Phosphoprotein
- Metablastin
- Prosolin
- Op18 Phosphoprotein
- Phosphoprotein, Op18
- Phosphoprotein p18
- p18, Phosphoprotein
- Phosphoprotein p19
- p19, Phosphoprotein
- Lap18 Protein
- Oncoprotein 18
|
Below are MeSH descriptors whose meaning is more general than "Stathmin".
Below are MeSH descriptors whose meaning is more specific than "Stathmin".
This graph shows the total number of publications written about "Stathmin" by people in this website by year, and whether "Stathmin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Stathmin" by people in Profiles.
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Schimmack S, Taylor A, Lawrence B, Schmitz-Winnenthal H, Fischer L, B?chler MW, Modlin IM, Kidd M, Tang LH. Stathmin in pancreatic neuroendocrine neoplasms: a marker of proliferation and PI3K signaling. Tumour Biol. 2015 Jan; 36(1):399-408.
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Ngo TT, Peng T, Liang XJ, Akeju O, Pastorino S, Zhang W, Kotliarov Y, Zenklusen JC, Fine HA, Maric D, Wen PY, De Girolami U, Black PM, Wu WW, Shen RF, Jeffries NO, Kang DW, Park JK. The 1p-encoded protein stathmin and resistance of malignant gliomas to nitrosoureas. J Natl Cancer Inst. 2007 Apr 18; 99(8):639-52.