Proto-Oncogene Proteins c-jun

"Proto-Oncogene Proteins c-jun" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cellular DNA-binding proteins encoded by the c-jun genes (GENES, JUN). They are involved in growth-related transcriptional control. There appear to be three distinct functions: dimerization (with c-fos), DNA-binding, and transcriptional activation. Oncogenic transformation can take place by constitutive expression of c-jun.

Descriptor ID	D016755
MeSH Number(s)	D12.776.260.108.820 D12.776.624.664.700.182 D12.776.660.763 D12.776.930.127.820
Concept/Terms	Proto-Oncogene Proteins c-jun Proto-Oncogene Proteins c-jun Proto Oncogene Proteins c jun c-jun Proteins c jun Proteins fos-Associated Protein p39 fos Associated Protein p39 jun Proto-Oncogene Product p39 jun Proto Oncogene Product p39 jun Proto-Oncogene Proteins jun Proto Oncogene Proteins p39 c-jun p39 c jun p39(c-jun) Proto-Oncogene Products c-jun Proto Oncogene Products c jun c-fos-Associated Protein p39 c fos Associated Protein p39 Proto-Oncogene Proteins jun Proto Oncogene Proteins jun jun D Proteins jun D Proteins jun B Proteins jun B Proteins

Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-jun".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic-Leucine Zipper Transcription Factors [D12.776.260.108]
Proto-Oncogene Proteins c-jun [D12.776.260.108.820]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]
Proto-Oncogene Proteins c-jun [D12.776.624.664.700.182]
Nuclear Proteins [D12.776.660]
Proto-Oncogene Proteins c-jun [D12.776.660.763]
Transcription Factors [D12.776.930]
Basic-Leucine Zipper Transcription Factors [D12.776.930.127]
Proto-Oncogene Proteins c-jun [D12.776.930.127.820]

Below are MeSH descriptors whose meaning is related to "Proto-Oncogene Proteins c-jun".

Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-jun".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Proto-Oncogene Proteins c-jun" by people in this website by year, and whether "Proto-Oncogene Proteins c-jun" was a major or minor topic of these publications.

Bar chart showing 21 publications over 14 distinct years, with a maximum of 2 publications in 1995 and 1997 and 2003 and 2006 and 2007 and 2008 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	2	0	2
1997	0	2	2
1998	1	0	1
1999	0	1	1
2002	0	1	1
2003	1	1	2
2006	1	1	2
2007	1	1	2
2008	2	0	2
2009	1	1	2
2015	0	1	1
2016	1	0	1
2018	1	0	1
2019	1	0	1

Below are the most recent publications written about "Proto-Oncogene Proteins c-jun" by people in Profiles.

Elliott B, Millena AC, Matyunina L, Zhang M, Zou J, Wang G, Zhang Q, Bowen N, Eaton V, Webb G, Thompson S, McDonald J, Khan S. Essential role of JunD in cell proliferation is mediated via MYC signaling in prostate cancer cells. Cancer Lett. 2019 04 28; 448:155-167.

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Maurer K, Ramen S, Shi L, Song L, Sullivan KE. Rapid induction of expression by LPS is accompanied by favorable chromatin and rapid binding of c-Jun. Mol Immunol. 2018 03; 95:99-106.

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Millena AC, Vo BT, Khan SA. JunD Is Required for Proliferation of Prostate Cancer Cells and Plays a Role in Transforming Growth Factor-? (TGF-?)-induced Inhibition of Cell Proliferation. J Biol Chem. 2016 08 19; 291(34):17964-76.

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Peng B, Chai Y, Li Y, Liu X, Zhang J. CIP2A overexpression induces autoimmune response and enhances JNK signaling pathway in human lung cancer. BMC Cancer. 2015 Nov 11; 15:895.

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Shi ZD, Ji XY, Berardi DE, Qazi H, Tarbell JM. Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanism. Am J Physiol Heart Circ Physiol. 2010 Jan; 298(1):H127-35.

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Mukhopadhyay S, Mukherjee S, Stone WL, Smith M, Das SK. Role of MAPK/AP-1 signaling pathway in the protection of CEES-induced lung injury by antioxidant liposome. Toxicology. 2009 Jul 10; 261(3):143-51.

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Jiang D, Zhou Y, Moxley RA, Jarrett HW. Purification and identification of positive regulators binding to a novel element in the c-Jun promoter. Biochemistry. 2008 Sep 02; 47(35):9318-34.

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Jia L, Yu W, Wang P, Li J, Sanders BG, Kline K. Critical roles for JNK, c-Jun, and Fas/FasL-Signaling in vitamin E analog-induced apoptosis in human prostate cancer cells. Prostate. 2008 Mar 01; 68(4):427-41.

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Thakur A, Wang X, Siedlak SL, Perry G, Smith MA, Zhu X. c-Jun phosphorylation in Alzheimer disease. J Neurosci Res. 2007 Jun; 85(8):1668-73.

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Yatsushige H, Ostrowski RP, Tsubokawa T, Colohan A, Zhang JH. Role of c-Jun N-terminal kinase in early brain injury after subarachnoid hemorrhage. J Neurosci Res. 2007 May 15; 85(7):1436-48.

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