CCAAT-Enhancer-Binding Proteins

"CCAAT-Enhancer-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of proteins that were originally identified by their ability to bind the DNA sequence CCAAT. The typical CCAAT-enhancer binding protein forms dimers and consists of an activation domain, a DNA-binding basic region, and a leucine-rich dimerization domain (LEUCINE ZIPPERS). CCAAT-BINDING FACTOR is structurally distinct type of CCAAT-enhancer binding protein consisting of a trimer of three different subunits.

Descriptor ID	D022762
MeSH Number(s)	D12.776.260.108.124 D12.776.660.167 D12.776.930.127.124
Concept/Terms	CCAAT-Enhancer-Binding Proteins CCAAT-Enhancer-Binding Proteins CCAAT Enhancer Binding Proteins CAAT-Enhancer Binding Protein Binding Protein, CAAT-Enhancer CAAT Enhancer Binding Protein CCAAT-Enhancer-Binding Protein CCAAT Enhancer Binding Protein C-EBP Protein C EBP Protein C-EBP Nuclear Protein C EBP Nuclear Protein Nuclear Protein, C-EBP CAAT-Enhancer-Binding Proteins CAAT Enhancer Binding Proteins C-EBP Proteins C EBP Proteins CCAAT Sequence-Specific DNA-Binding Proteins CCAAT Sequence Specific DNA Binding Proteins Nuclear Protein C-EBP C-EBP, Nuclear Protein Nuclear Protein C EBP

Below are MeSH descriptors whose meaning is more general than "CCAAT-Enhancer-Binding Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic-Leucine Zipper Transcription Factors [D12.776.260.108]
CCAAT-Enhancer-Binding Proteins [D12.776.260.108.124]
Nuclear Proteins [D12.776.660]
CCAAT-Enhancer-Binding Proteins [D12.776.660.167]
Transcription Factors [D12.776.930]
Basic-Leucine Zipper Transcription Factors [D12.776.930.127]
CCAAT-Enhancer-Binding Proteins [D12.776.930.127.124]

Below are MeSH descriptors whose meaning is related to "CCAAT-Enhancer-Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "CCAAT-Enhancer-Binding Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CCAAT-Enhancer-Binding Proteins" by people in this website by year, and whether "CCAAT-Enhancer-Binding Proteins" was a major or minor topic of these publications.

Bar chart showing 23 publications over 16 distinct years, with a maximum of 3 publications in 2001

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	0	2	2
1999	0	1	1
2000	0	1	1
2001	1	2	3
2002	0	1	1
2005	0	1	1
2008	0	1	1
2009	0	1	1
2011	1	1	2
2013	1	0	1
2014	1	1	2
2015	0	2	2
2016	1	0	1
2017	0	1	1
2018	0	2	2

Below are the most recent publications written about "CCAAT-Enhancer-Binding Proteins" by people in Profiles.

Krishnan V, Baskaran P, Thyagarajan B. Troglitazone activates TRPV1 and causes deacetylation of PPAR? in 3T3-L1 cells. Biochim Biophys Acta Mol Basis Dis. 2019 02 01; 1865(2):445-453.

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Diep DTV, Hong K, Khun T, Zheng M, Ul-Haq A, Jun HS, Kim YB, Chun KH. Anti-adipogenic effects of KD025 (SLx-2119), a ROCK2-specific inhibitor, in 3T3-L1 cells. Sci Rep. 2018 02 06; 8(1):2477.

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Forno E, Sordillo J, Brehm J, Chen W, Benos T, Yan Q, Avila L, Soto-Quir?s M, Cloutier MM, Col?n-Semidey A, Alvarez M, Acosta-P?rez E, Weiss ST, Litonjua AA, Canino G, Celed?n JC. Genome-wide interaction study of dust mite allergen on lung function in children with asthma. J Allergy Clin Immunol. 2017 Oct; 140(4):996-1003.e7.

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Roy SS, Mukherjee S, Das SK. Effects of intratracheal exposure of 2-chloroethyl ethyl sulfide (CEES) on the activation of CCAAT-enhancer-binding protein (C/EBP) and its protection by antioxidant liposome. J Biochem Mol Toxicol. 2017 May; 31(5).

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Jia Y, Jarrett HW. Method for trapping affinity chromatography of transcription factors using aldehyde-hydrazide coupling to agarose. Anal Biochem. 2015 Aug 01; 482:1-6.

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Nagore LI, Jarrett HW. T(3): targeted proteomics of DNA-binding proteins. Anal Biochem. 2015 Apr 01; 474:8-15.

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Bhaumik P, Davis J, Tropea JE, Cherry S, Johnson PF, Miller M. Structural insights into interactions of C/EBP transcriptional activators with the Taz2 domain of p300. Acta Crystallogr D Biol Crystallogr. 2014 Jul; 70(Pt 7):1914-21.

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Jia Y, Larionov O, Jarrett HW. Coupling of deoxyribonucleic acid to solid supports using 3' terminal ribose incorporation. J Chromatogr A. 2014 Apr 25; 1339:73-9.

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Nookala AR, Shah A, Noel RJ, Kumar A. HIV-1 Tat-mediated induction of CCL5 in astrocytes involves NF-?B, AP-1, C/EBPa and C/EBP? transcription factors and JAK, PI3K/Akt and p38 MAPK signaling pathways. PLoS One. 2013; 8(11):e78855.

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Zhang R, Kim YM, Yang X, Li Y, Li S, Lee JY. A possible 5'-NRIP1/UHRF1-3' fusion gene detected by array CGH analysis in a Ph+ ALL patient. Cancer Genet. 2011 Dec; 204(12):687-91.

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