DNA

"DNA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).

Descriptor ID	D004247
MeSH Number(s)	D13.444.308
Concept/Terms	DNA DNA Deoxyribonucleic Acid DNA, Double-Stranded DNA, Double-Stranded DNA, Double Stranded Double-Stranded DNA ds-DNA ds DNA

Below are MeSH descriptors whose meaning is more general than "DNA".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
DNA [D13.444.308]

Below are MeSH descriptors whose meaning is related to "DNA".

Below are MeSH descriptors whose meaning is more specific than "DNA".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA" by people in this website by year, and whether "DNA" was a major or minor topic of these publications.

Bar chart showing 424 publications over 30 distinct years, with a maximum of 29 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	5	9	14
1997	5	3	8
1998	6	5	11
1999	2	10	12
2000	8	8	16
2001	6	7	13
2002	9	16	25
2003	8	13	21
2004	9	15	24
2005	9	16	25
2006	10	19	29
2007	7	10	17
2008	11	10	21
2009	8	14	22
2010	8	10	18
2011	9	9	18
2012	11	7	18
2013	4	7	11
2014	7	6	13
2015	9	7	16
2016	8	1	9
2017	5	4	9
2018	2	3	5
2019	4	4	8
2020	2	3	5
2021	4	4	8
2022	1	9	10
2023	0	7	7
2024	1	6	7
2025	4	0	4

Below are the most recent publications written about "DNA" by people in Profiles.

Short JE, Sharek L, Meckler JF, Stoytchev I, Tran CT, Errard C, Hew BE, Johnson BE, Waller DF, Xie S, Higgins JJ, Tabibiazar R, Owens JB. Gene-sized DNA insertion at genomic safe harbors in human cells using a site-directed transposase. Nucleic Acids Res. 2025 Nov 26; 53(22).

View in: PubMed
Udeochu U, Smith C, Kong S, Adebayo A, Franklin J, Bakare O. Spectroscopic Investigation of Emetine-DNA Binding. J Med Chem. 2025 Dec 11; 68(23):25375-25384.

View in: PubMed
Chambers JK, Watanabe K, Michishita M, Hatai H, Tanaka Y, Doge S, Ochiai K, Kato S, Goto-Koshino Y, Tanaka M, Izawa T. Standardization of tissue handling in veterinary pathology: How fixation affects morphological and molecular examination results. Vet Pathol. 2025 Nov; 62(6):949-962.

View in: PubMed
van Heesch T, Sharma S, van Erp B, Ort?z APA, Dame RT, Vreede J, Gavvala K. Adaptation of DNA to Protein Binding Revealed by Spectroscopy and Molecular Simulation. J Phys Chem B. 2025 Jun 12; 129(23):5653-5663.

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O'Neal P, Washington K, Estes B, Chandran PL. A Facile and Versatile Platform for Cytosolic Delivery of Proteins in Nanoshells of DNA or RNA: Packaging Options in Multiplexed Delivery. Biomacromolecules. 2025 May 12; 26(5):3084-3103.

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Olawoye O, Young BP, Nyunt AW, Fafowora OF, Ajani M, Sarimiye T, Creemer BA, Roos BR, Coleman AL, Gorin MB, Hauser MA, Scheetz TE, Ashaye A, Fingert JH. Prevalence of Myocilin Mutations in a Cohort of Patients with Juvenile Open-Angle Glaucoma from sub-Saharan Africa. Ophthalmol Glaucoma. 2025 Sep-Oct; 8(5):450-456.

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Hesko O, Pivonkov? H, Fojt L, Taylor A, Kopecek J, Schwarzov?-Peckov? K, Fojta M. Characterization of boron doped diamond electrodes with engineered sp2 carbon content and their application to structure-dependent DNA hybridization. Bioelectrochemistry. 2025 Aug; 164:108910.

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Zhang T, Liu S, Durojaye O, Xiong F, Fang Z, Ullah T, Fu C, Sun B, Jiang H, Xia P, Wang Z, Yao X, Liu X. Dynamic phosphorylation of FOXA1 by Aurora B guides post-mitotic gene reactivation. Cell Rep. 2024 09 24; 43(9):114739.

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Islam SM, Hasan MM, Alam J, Dey A, Molineaux D. In Silico Screening, Molecular Dynamics Simulation and Binding Free Energy Identify Single-Point Mutations That Destabilize p53 and Reduce Binding to DNA. Proteins. 2025 Feb; 93(2):498-514.

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Zhu N, Rogers WE, Heidary DK, Huxford T. Structural and biochemical analyses of the nuclear I?B? protein in complex with the NF-?B p50 homodimer. Genes Dev. 2024 07 19; 38(11-12):528-535.

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