"DNA, Circular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)
| Descriptor ID |
D004270
|
| MeSH Number(s) |
D13.444.308.283 G02.111.570.820.486.212 G05.360.580.156
|
| Concept/Terms |
DNA, Circular- DNA, Circular
- Circular DNAs
- DNAs, Circular
- Circular DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA, Circular".
Below are MeSH descriptors whose meaning is more specific than "DNA, Circular".
This graph shows the total number of publications written about "DNA, Circular" by people in this website by year, and whether "DNA, Circular" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA, Circular" by people in Profiles.
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Tarasova E, Khayat R. A Structural Perspective of Reps from CRESS-DNA Viruses and Their Bacterial Plasmid Homologues. Viruses. 2021 12 25; 14(1).
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Gopalakrishnan AM, Kundu AK, Mandal TK, Kumar N. Novel nanosomes for gene delivery to Plasmodium falciparum-infected red blood cells. Sci Rep. 2013; 3:1534.
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Seidl CI, Lama L, Ryan K. Circularized synthetic oligodeoxynucleotides serve as promoterless RNA polymerase III templates for small RNA generation in human cells. Nucleic Acids Res. 2013 Feb 01; 41(4):2552-64.
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Seidl CI, Ryan K. Circular single-stranded synthetic DNA delivery vectors for microRNA. PLoS One. 2011 Feb 16; 6(2):e16925.
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Miles LR, Agresta BE, Khan MB, Tang S, Levin JG, Powell MD. Effect of polypurine tract (PPT) mutations on human immunodeficiency virus type 1 replication: a virus with a completely randomized PPT retains low infectivity. J Virol. 2005 Jun; 79(11):6859-67.
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Henegariu O, Grober L, Haskins W, Bowers PN, State MW, Ohmido N, Bray-Ward P, Ward DC. Rapid DNA fiber technique for size measurements of linear and circular DNA probes. Biotechniques. 2001 Aug; 31(2):246-50.
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Valenzuela MS, Bardhan S, Krishnamani MR, Siddiqui KA. Catenated dimers and knotted DNA structures: putative intermediates in the replication of T. cruzi kinetoplast minicircle DNA. Biochem Biophys Res Commun. 1991 Jan 31; 174(2):958-68.
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Jenab S, Johnson EM. A dual-circular plasmid structure dependent on DNA replication generated in monkey COS7 cells and cell extracts. Biochem Biophys Res Commun. 1989 Apr 14; 160(1):53-9.
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Sunter G, Coutts RH, Buck KW. Negatively supercoiled DNA from plants infected with a single-stranded DNA virus. Biochem Biophys Res Commun. 1984 Feb 14; 118(3):747-52.
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Valenzuela MS, Inman RB. Visualization of a novel junction in bacteriophage lambda DNA. Proc Natl Acad Sci U S A. 1975 Aug; 72(8):3024-8.