"DNA, Superhelical" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Circular duplex DNA isolated from viruses, bacteria and mitochondria in supercoiled or supertwisted form. This superhelical DNA is endowed with free energy. During transcription, the magnitude of RNA initiation is proportional to the DNA superhelicity.
| Descriptor ID |
D004278
|
| MeSH Number(s) |
D13.444.308.283.250 G02.111.570.820.486.212.250 G05.360.580.156.250
|
| Concept/Terms |
DNA, Superhelical- DNA, Superhelical
- Superhelical DNA
- DNA, Supertwisted
- Supertwisted DNA
- DNA, Supercoiled
- Supercoiled DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA, Superhelical".
Below are MeSH descriptors whose meaning is more specific than "DNA, Superhelical".
This graph shows the total number of publications written about "DNA, Superhelical" by people in this website by year, and whether "DNA, Superhelical" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA, Superhelical" by people in Profiles.
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Sanabria-R?os DJ, Rivera-Torres Y, Rosario J, Gutierrez R, Torres-Garc?a Y, Montano N, Ort?z-Soto G, R?os-Olivares E, Rodr?guez JW, Carballeira NM. Chemical conjugation of 2-hexadecynoic acid to C5-curcumin enhances its antibacterial activity against multi-drug resistant bacteria. Bioorg Med Chem Lett. 2015 Nov 15; 25(22):5067-71.
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Ward WS. Regulating DNA supercoiling: sperm points the way. Biol Reprod. 2011 May; 84(5):841-3.
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Brosh RM, Sharma S. Biochemical assays for the characterization of DNA helicases. Methods Mol Biol. 2006; 314:397-415.
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Wang S, Yu H. Effect of co-existing biologically relevant molecules and ions on DNA photocleavage caused by pyrene and its derivatives. Int J Environ Res Public Health. 2005 Apr; 2(1):132-7.
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Vivas-Mej?a PE, Cox O, Gonz?lez FA. Inhibition of human topoisomerase II by anti-neoplastic benzazolo[3,2-alpha]quinolinium chlorides. Mol Cell Biochem. 1998 Jan; 178(1-2):203-12.
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Valenzuela MS, Siddiqui KA. Bidirectional sequencing of supercoiled plasmid DNA. Anal Biochem. 1989 Dec; 183(2):258-62.
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Sunter G, Buck KW, Coutts RH. S1-sensitive sites in the supercoiled double-stranded form of tomato golden mosaic virus DNA component B: identification of regions of potential alternative secondary structure and regulatory function. Nucleic Acids Res. 1985 Jul 11; 13(13):4645-59.
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Sunter G, Coutts RH, Buck KW. Negatively supercoiled DNA from plants infected with a single-stranded DNA virus. Biochem Biophys Res Commun. 1984 Feb 14; 118(3):747-52.