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Garry Sunter

TitleProfessor Plant Molecular Virology
Faculty RankProfessor
InstitutionUniversity of Texas at San Antonio
DepartmentBiology
AddressOne UTSA Circle
San Antonio TX 78256
Phone210-458-5479
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    The main focus of Dr. Sunter’s research is directed toward the study of plant gene expression, DNA replication, and plant-pathogen interactions using single-stranded DNA plant viruses of the family Geminiviridae as a model system. One aspect of the research involves transcriptional regulation. In many viral systems, gene expression follows a temporal sequence that is closely coordinated and during the initial stages of infection viral DNA replication and transcription rely entirely on the host and in many cases some of the viral proteins initially expressed are subsequently involved in the regulation of other viral genes. Dr. Sunter is particularly interested in two viral genes that are involved in replication and transcription of the viral genome. The coordinate regulation of these genes appears crucial to ensure correct timing of both replication and transcription and may well reveal novel mechanisms and insights into plant transcription mechanisms.
    A second interest involves the role of viral genes in host gene activation. Geminiviruses rely primarily on host replication and transcriptional machinery to express their genes and amplify their genomic DNA. To overcome the inherent inability of plant cells to replicate viral DNA, geminiviruses must in some way make cells receptive to replication and transcription of the virus. In animals, many DNA viruses are capable of altering the host cell to facilitate efficient replication and transcription of viral DNA, either by direct activation of host gene expression or by interacting with cellular transcription factors. These interactions in turn induce expression of genes encoding proteins required for DNA replication and cell cycle progression. Dr. Sunter is interested in identifying cellular genes activated and/or repressed by the virus and elucidating mechanisms by which the virus interacts with these proteins.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Williams J, Regedanz E, Lucinda N, Nava Fereira AR, Lacatus G, Berger M, O'Connell N, Coursey T, Ruan J, Bisaro DM, Sunter G. Mutation of the conserved late element in geminivirus CP promoters abolishes Arabidopsis TCP24 transcription factor binding and decreases H3K27me3 levels on viral chromatin. PLoS Pathog. 2024 Jul; 20(7):e1012399. PMID: 39024402.
      Citations:    Fields:    Translation:AnimalsCells
    2. Najnin T, Saimon SH, Sunter G, Ruan J. A Network-Based Approach for Improving Annotation of Transcription Factor Functions and Binding Sites in Arabidopsis thaliana. Genes (Basel). 2023 01 21; 14(2). PMID: 36833209.
      Citations:    Fields:    Translation:AnimalsCells
    3. Feng H, Acosta-Gamboa L, Kruse LH, Tracy JD, Chung SH, Nava Fereira AR, Shakir S, Xu H, Sunter G, Gore MA, Casteel CL, Moghe GD, Jander G. Acylsugars protect Nicotiana benthamiana against insect herbivory and desiccation. Plant Mol Biol. 2022 Jul; 109(4-5):505-522. PMID: 34586580.
      Citations: 4     Fields:    Translation:AnimalsCells
    4. Ogden AJ, Boukari W, Nava A, Lucinda N, Sunter G, Curtis WR, Adkins JN, Polston JE. Characterization of Local and Systemic Impact of Whitefly (Bemisia tabaci) Feeding and Whitefly-Transmitted Tomato Mottle Virus Infection on Tomato Leaves by Comprehensive Proteomics. Int J Mol Sci. 2020 Sep 30; 21(19). PMID: 33008056.
      Citations: 4     Fields:    Translation:AnimalsCells
    5. Guerrero J, Regedanz E, Lu L, Ruan J, Bisaro DM, Sunter G. Manipulation of the Plant Host by the Geminivirus AC2/C2 Protein, a Central Player in the Infection Cycle. Front Plant Sci. 2020; 11:591. PMID: 32508858.
      Citations:    
    6. Guerrero J, Sunter G. Complementary-sense gene regulation in beet curly top virus-SpCT. Arch Virol. 2019 Nov; 164(11):2823-2828. PMID: 31485748.
      Citations:    Fields:    Translation:Cells
    7. Yang X, Guo W, Li F, Sunter G, Zhou X. Geminivirus-Associated Betasatellites: Exploiting Chinks in the Antiviral Arsenal of Plants. Trends Plant Sci. 2019 06; 24(6):519-529. PMID: 31003895.
      Citations: 29     Fields:    Translation:AnimalsCells
    8. Mei Y, Wang Y, Hu T, Yang X, Lozano-Duran R, Sunter G, Zhou X. Nucleocytoplasmic Shuttling of Geminivirus C4?Protein Mediated by Phosphorylation and Myristoylation Is Critical for Viral Pathogenicity. Mol Plant. 2018 12 03; 11(12):1466-1481. PMID: 30523782.
      Citations: 30     Fields:    Translation:Cells
    9. Xie L, Shang W, Liu C, Zhang Q, Sunter G, Hong J, Zhou X. Mutual association of Broad bean wilt virus 2 VP37-derived tubules and plasmodesmata obtained from cytological observation. Sci Rep. 2016 Feb 23; 6:21552. PMID: 26903400.
      Citations: 9     Fields:    Translation:AnimalsCells
    10. Qian Y, Hou H, Shen Q, Cai X, Sunter G, Zhou X. RepA Protein Encoded by Oat dwarf virus Elicits a Temperature-Sensitive Hypersensitive Response-Type Cell Death That Involves Jasmonic Acid-Dependent Signaling. Mol Plant Microbe Interact. 2016 Jan; 29(1):5-21. PMID: 26720685.
      Citations: 5     Fields:    Translation:AnimalsCells
    11. Liu L, Chung HY, Lacatus G, Baliji S, Ruan J, Sunter G. Altered expression of Arabidopsis genes in response to a multifunctional geminivirus pathogenicity protein. BMC Plant Biol. 2014 Nov 18; 14:302. PMID: 25403083.
      Citations: 10     Fields:    Translation:AnimalsCells
    12. Kong L, Wang Y, Yang X, Sunter G, Zhou X. Broad bean wilt virus 2 encoded VP53, VP37 and large capsid protein orchestrate suppression of RNA silencing in plant. Virus Res. 2014 Nov 04; 192:62-73. PMID: 25173697.
      Citations: 6     Fields:    Translation:AnimalsCells
    13. Chung HY, Sunter G. Interaction between the transcription factor AtTIFY4B and begomovirus AL2 protein impacts pathogenicity. Plant Mol Biol. 2014 Sep; 86(1-2):185-200. PMID: 25011501.
      Citations: 11     Fields:    Translation:AnimalsCells
    14. Yong Chung H, Lacatus G, Sunter G. Geminivirus AL2 protein induces expression of, and interacts with, a calmodulin-like gene, an endogenous regulator of gene silencing. Virology. 2014 Jul; 460-461:108-18. PMID: 25010276.
      Citations: 26     Fields:    Translation:AnimalsCells
    15. Berger MR, Sunter G. Identification of sequences required for AL2-mediated activation of the tomato golden mosaic virus-yellow vein BR1 promoter. J Gen Virol. 2013 Jun; 94(Pt 6):1398-1406. PMID: 23486662.
      Citations: 8     Fields:    Translation:AnimalsCells
    16. Rao K, Sunter G. Sequences within the Spinach curly top virus virion sense promoter are necessary for vascular-specific expression of virion sense genes. Virology. 2012 Oct 10; 432(1):10-9. PMID: 22727833.
      Citations: 3     Fields:    Translation:AnimalsCells
    17. Ruan J, Perez J, Hernandez B, Lei C, Sunter G, Sponsel VM. Systematic identification of functional modules and cis-regulatory elements in Arabidopsis thaliana. BMC Bioinformatics. 2011 Nov 24; 12 Suppl 12:S2. PMID: 22168340.
      Citations: 5     Fields:    Translation:AnimalsCells
    18. Chung HY, Lee HH, Kim KI, Chung HY, Hwang-Bo J, Park JH, Sunter G, Kim JB, Shon DH, Kim W, Chung IS. Expression of a recombinant chimeric protein of hepatitis A virus VP1-Fc using a replicating vector based on Beet curly top virus in tobacco leaves and its immunogenicity in mice. Plant Cell Rep. 2011 Aug; 30(8):1513-21. PMID: 21442402.
      Citations: 15     Fields:    Translation:AnimalsCellsPHPublic Health
    19. Baliji S, Lacatus G, Sunter G. The interaction between geminivirus pathogenicity proteins and adenosine kinase leads to increased expression of primary cytokinin-responsive genes. Virology. 2010 Jul 05; 402(2):238-47. PMID: 20399479.
      Citations: 31     Fields:    Translation:AnimalsCells
    20. Lacatus G, Sunter G. The Arabidopsis PEAPOD2 transcription factor interacts with geminivirus AL2 protein and the coat protein promoter. Virology. 2009 Sep 30; 392(2):196-202. PMID: 19647846.
      Citations: 30     Fields:    Translation:AnimalsCells
    21. Shung CY, Sunter G. Regulation of Tomato golden mosaic virus AL2 and AL3 gene expression by a conserved upstream open reading frame. Virology. 2009 Jan 20; 383(2):310-8. PMID: 19012941.
      Citations: 7     Fields:    Translation:AnimalsCells
    22. Lacatus G, Sunter G. Functional analysis of bipartite begomovirus coat protein promoter sequences. Virology. 2008 Jun 20; 376(1):79-89. PMID: 18430450.
      Citations: 11     Fields:    Translation:AnimalsCells
    23. Yang X, Baliji S, Buchmann RC, Wang H, Lindbo JA, Sunter G, Bisaro DM. Functional modulation of the geminivirus AL2 transcription factor and silencing suppressor by self-interaction. J Virol. 2007 Nov; 81(21):11972-81. PMID: 17715241.
      Citations: 51     Fields:    Translation:AnimalsCells
    24. Tu J, Sunter G. A conserved binding site within the Tomato golden mosaic virus AL-1629 promoter is necessary for expression of viral genes important for pathogenesis. Virology. 2007 Oct 10; 367(1):117-25. PMID: 17532021.
      Citations: 6     Fields:    Translation:AnimalsCells
    25. Shung CY, Sunter G. AL1-dependent repression of transcription enhances expression of Tomato golden mosaic virus AL2 and AL3. Virology. 2007 Jul 20; 364(1):112-22. PMID: 17407785.
      Citations: 10     Fields:    Translation:AnimalsCells
    26. Kim KI, Sunter G, Bisaro DM, Chung IS. Improved expression of recombinant GFP using a replicating vector based on Beet curly top virus in leaf-disks and infiltrated Nicotiana benthamiana leaves. Plant Mol Biol. 2007 May; 64(1-2):103-12. PMID: 17294255.
      Citations: 12     Fields:    Translation:AnimalsCells
    27. Baliji S, Sunter J, Sunter G. Transcriptional analysis of complementary sense genes in Spinach curly top virus and functional role of C2 in pathogenesis. Mol Plant Microbe Interact. 2007 Feb; 20(2):194-206. PMID: 17313170.
      Citations: 25     Fields:    Translation:AnimalsCells
    28. Shung CY, Sunter J, Sirasanagandla SS, Sunter G. Distinct viral sequence elements are necessary for expression of Tomato golden mosaic virus complementary sense transcripts that direct AL2 and AL3 gene expression. Mol Plant Microbe Interact. 2006 Dec; 19(12):1394-405. PMID: 17153924.
      Citations: 10     Fields:    Translation:AnimalsCells
    29. Hong SH, Kim KI, Chung HY, Kim YJ, Sunter G, Bisaro DM, Chung IS. Expression of recombinant endostatin in Agrobacterium-inoculated leaf disks of Nicotiana tabacum var. Xanthi. Biotechnol Lett. 2004 Sep; 26(18):1433-9. PMID: 15604777.
      Citations: 1     Fields:    Translation:AnimalsCells
    30. Baliji S, Black MC, French R, Stenger DC, Sunter G. Spinach curly top virus: A Newly Described Curtovirus Species from Southwest Texas with Incongruent Gene Phylogenies. Phytopathology. 2004 Jul; 94(7):772-9. PMID: 18943911.
      Citations: 8     Fields:    
    31. Wang H, Hao L, Shung CY, Sunter G, Bisaro DM. Adenosine kinase is inactivated by geminivirus AL2 and L2 proteins. Plant Cell. 2003 Dec; 15(12):3020-32. PMID: 14615595.
      Citations: 80     Fields:    Translation:AnimalsCells
    32. Hao L, Wang H, Sunter G, Bisaro DM. Geminivirus AL2 and L2 proteins interact with and inactivate SNF1 kinase. Plant Cell. 2003 Apr; 15(4):1034-48. PMID: 12671096.
      Citations: 94     Fields:    Translation:AnimalsCells
    33. Sunter G, Bisaro DM. Identification of a minimal sequence required for activation of the tomato golden mosaic virus coat protein promoter in protoplasts. Virology. 2003 Jan 20; 305(2):452-62. PMID: 12573590.
      Citations: 33     Fields:    Translation:AnimalsCells
    34. Sunter G, Sunter JL, Bisaro DM. Plants expressing tomato golden mosaic virus AL2 or beet curly top virus L2 transgenes show enhanced susceptibility to infection by DNA and RNA viruses. Virology. 2001 Jun 20; 285(1):59-70. PMID: 11414806.
      Citations: 41     Fields:    Translation:AnimalsCells
    35. Hartitz MD, Sunter G, Bisaro DM. The tomato golden mosaic virus transactivator (TrAP) is a single-stranded DNA and zinc-binding phosphoprotein with an acidic activation domain. Virology. 1999 Oct 10; 263(1):1-14. PMID: 10544077.
      Citations: 38     Fields:    Translation:AnimalsCells
    36. Sunter G, Bisaro DM. Regulation of a geminivirus coat protein promoter by AL2 protein (TrAP): evidence for activation and derepression mechanisms. Virology. 1997 Jun 09; 232(2):269-80. PMID: 9191840.
      Citations: 36     Fields:    Translation:Cells
    37. Sunter G, Stenger DC, Bisaro DM. Heterologous complementation by geminivirus AL2 and AL3 genes. Virology. 1994 Sep; 203(2):203-10. PMID: 8053144.
      Citations: 24     Fields:    Translation:Cells
    38. Sunter G, Hartitz MD, Bisaro DM. Tomato golden mosaic virus leftward gene expression: autoregulation of geminivirus replication protein. Virology. 1993 Jul; 195(1):275-80. PMID: 8317105.
      Citations: 34     Fields:    Translation:AnimalsCells
    39. Sunter G, Bisaro DM. Transactivation of geminivirus AR1 and BR1 gene expression by the viral AL2 gene product occurs at the level of transcription. Plant Cell. 1992 Oct; 4(10):1321-31. PMID: 1446172.
      Citations: 82     Fields:    Translation:Cells
    40. Brough CL, Sunter G, Gardiner WE, Bisaro DM. Kinetics of tomato golden mosaic virus DNA replication and coat protein promoter activity in Nicotiana tabacum protoplasts. Virology. 1992 Mar; 187(1):1-9. PMID: 1736521.
      Citations: 12     Fields:    Translation:AnimalsCells
    41. Sunter G, Bisaro DM. Transactivation in a geminivirus: AL2 gene product is needed for coat protein expression. Virology. 1991 Jan; 180(1):416-9. PMID: 1984661.
      Citations: 33     Fields:    Translation:Cells
    42. Sunter G, Hartitz MD, Hormuzdi SG, Brough CL, Bisaro DM. Genetic analysis of tomato golden mosaic virus: ORF AL2 is required for coat protein accumulation while ORF AL3 is necessary for efficient DNA replication. Virology. 1990 Nov; 179(1):69-77. PMID: 2219741.
      Citations: 62     Fields:    Translation:AnimalsCells
    43. Sunter G, Bisaro DM. Transcription map of the B genome component of tomato golden mosaic virus and comparison with A component transcripts. Virology. 1989 Dec; 173(2):647-55. PMID: 2596033.
      Citations: 19     Fields:    Translation:Cells
    44. Revington GN, Sunter G, Bisaro DM. DNA sequences essential for replication of the B genome component of tomato golden mosaic virus. Plant Cell. 1989 Oct; 1(10):985-92. PMID: 2562558.
      Citations: 21     Fields:    Translation:AnimalsCells
    45. Sunter G, Gardiner WE, Bisaro DM. Identification of tomato golden mosaic virus-specific RNAs in infected plants. Virology. 1989 May; 170(1):243-50. PMID: 2541538.
      Citations: 21     Fields:    Translation:AnimalsCells
    46. Elmer JS, Brand L, Sunter G, Gardiner WE, Bisaro DM, Rogers SG. Genetic analysis of the tomato golden mosaic virus. II. The product of the AL1 coding sequence is required for replication. Nucleic Acids Res. 1988 Jul 25; 16(14B):7043-60. PMID: 3405758.
      Citations: 80     Fields:    Translation:Cells
    47. Gardiner WE, Sunter G, Brand L, Elmer JS, Rogers SG, Bisaro DM. Genetic analysis of tomato golden mosaic virus: the coat protein is not required for systemic spread or symptom development. EMBO J. 1988 Apr; 7(4):899-904. PMID: 16453835.
      Citations: 37     Fields:    
    48. Sunter G, Buck KW, Coutts RH. S1-sensitive sites in the supercoiled double-stranded form of tomato golden mosaic virus DNA component B: identification of regions of potential alternative secondary structure and regulatory function. Nucleic Acids Res. 1985 Jul 11; 13(13):4645-59. PMID: 2991843.
      Citations: 6     Fields:    Translation:Cells
    49. Sunter G, Coutts RH, Buck KW. Negatively supercoiled DNA from plants infected with a single-stranded DNA virus. Biochem Biophys Res Commun. 1984 Feb 14; 118(3):747-52. PMID: 6322762.
      Citations: 10     Fields:    Translation:AnimalsCells
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