Transcription Factor AP-1

"Transcription Factor AP-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.

Descriptor ID	D018808
MeSH Number(s)	D12.776.260.108.875 D12.776.930.127.875
Concept/Terms	Transcription Factor AP-1 Transcription Factor AP-1 Transcription Factor AP 1 AP-1 Enhancer-Binding Protein Enhancer-Binding Protein, AP-1 AP-1 Activator Protein-1 Activator Protein 1 AP-1 Enhancer Binding Protein AP 1 Enhancer Binding Protein

Below are MeSH descriptors whose meaning is more general than "Transcription Factor AP-1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic-Leucine Zipper Transcription Factors [D12.776.260.108]
Transcription Factor AP-1 [D12.776.260.108.875]
Transcription Factors [D12.776.930]
Basic-Leucine Zipper Transcription Factors [D12.776.930.127]
Transcription Factor AP-1 [D12.776.930.127.875]

Below are MeSH descriptors whose meaning is related to "Transcription Factor AP-1".

Below are MeSH descriptors whose meaning is more specific than "Transcription Factor AP-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Transcription Factor AP-1" by people in this website by year, and whether "Transcription Factor AP-1" was a major or minor topic of these publications.

Bar chart showing 27 publications over 14 distinct years, with a maximum of 5 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	1	1	2
2002	1	0	1
2003	0	1	1
2006	2	3	5
2007	2	0	2
2008	2	0	2
2009	1	1	2
2010	0	1	1
2011	2	2	4
2012	0	1	1
2013	1	0	1
2015	0	3	3
2016	0	1	1

Below are the most recent publications written about "Transcription Factor AP-1" by people in Profiles.

Jameson NM, Ma J, Benitez J, Izurieta A, Han JY, Mendez R, Parisian A, Furnari F. Intron 1-Mediated Regulation of EGFR Expression in EGFR-Dependent Malignancies Is Mediated by AP-1 and BET Proteins. Mol Cancer Res. 2019 11; 17(11):2208-2220.

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Jung SK, Ha SJ, Jung CH, Kim YT, Lee HK, Kim MO, Lee MH, Mottamal M, Bode AM, Lee KW, Dong Z. Naringenin targets ERK2 and suppresses UVB-induced photoaging. J Cell Mol Med. 2016 May; 20(5):909-19.

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Kumar NV, Yang J, Pillai JK, Rawat S, Solano C, Kumar A, Gr?tli M, Stemmler TL, Rosen BP, Tam?s MJ. Arsenic Directly Binds to and Activates the Yeast AP-1-Like Transcription Factor Yap8. Mol Cell Biol. 2015 Dec 28; 36(6):913-22.

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Torres OV, McCoy MT, Ladenheim B, Jayanthi S, Brannock C, Tulloch I, Krasnova IN, Cadet JL. CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens. Sci Rep. 2015 Aug 24; 5:13396.

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West RJ, Lu Y, Marie B, Gao FB, Sweeney ST. Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia. J Cell Biol. 2015 Mar 30; 208(7):931-47.

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Nookala AR, Shah A, Noel RJ, Kumar A. HIV-1 Tat-mediated induction of CCL5 in astrocytes involves NF-?B, AP-1, C/EBPa and C/EBP? transcription factors and JAK, PI3K/Akt and p38 MAPK signaling pathways. PLoS One. 2013; 8(11):e78855.

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Higa JK, Liang Z, Williams PG, Panee J. Phyllostachys edulis compounds inhibit palmitic acid-induced monocyte chemoattractant protein 1 (MCP-1) production. PLoS One. 2012; 7(9):e45082.

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Zhou YW, Munoz J, Jiang D, Jarrett HW. Laminin-a1 LG4-5 domain binding to dystroglycan mediates muscle cell survival, growth, and the AP-1 and NF-?B transcription factors but also has adverse effects. Am J Physiol Cell Physiol. 2012 Mar 15; 302(6):C902-14.

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Li J, Mottamal M, Li H, Liu K, Zhu F, Cho YY, Sosa CP, Zhou K, Bowden GT, Bode AM, Dong Z. Quercetin-3-methyl ether suppresses proliferation of mouse epidermal JB6 P+ cells by targeting ERKs. Carcinogenesis. 2012 Feb; 33(2):459-65.

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Jiang D, Jia Y, Jarrett HW. Transcription factor proteomics: identification by a novel gel mobility shift-three-dimensional electrophoresis method coupled with southwestern blot and high-performance liquid chromatography-electrospray-mass spectrometry analysis. J Chromatogr A. 2011 Sep 28; 1218(39):7003-15.

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