Positive Transcriptional Elongation Factor B

"Positive Transcriptional Elongation Factor B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A transcriptional elongation factor complex that is comprised of a heterodimer of CYCLIN-DEPENDENT KINASE 9 and one of several CYCLINS including TYPE T CYCLINS and cyclin K. It functions by phosphorylating the carboxy-terminal domain of RNA POLYMERASE II.

Descriptor ID	D042925
MeSH Number(s)	D08.811.913.696.620.682.700.626 D12.776.930.955.500
Concept/Terms	Positive Transcriptional Elongation Factor B Positive Transcriptional Elongation Factor B Positive Transcription Elongation Factor B tat-Associated Kinase tat Associated Kinase P-TEFb

Below are MeSH descriptors whose meaning is more general than "Positive Transcriptional Elongation Factor B".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
Positive Transcriptional Elongation Factor B [D08.811.913.696.620.682.700.626]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Transcription Factors [D12.776.930]
Transcriptional Elongation Factors [D12.776.930.955]
Positive Transcriptional Elongation Factor B [D12.776.930.955.500]

Below are MeSH descriptors whose meaning is related to "Positive Transcriptional Elongation Factor B".

Below are MeSH descriptors whose meaning is more specific than "Positive Transcriptional Elongation Factor B".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Positive Transcriptional Elongation Factor B" by people in this website by year, and whether "Positive Transcriptional Elongation Factor B" was a major or minor topic of these publications.

Bar chart showing 10 publications over 8 distinct years, with a maximum of 2 publications in 2012 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2007	1	0	1
2012	0	2	2
2013	1	1	2
2015	0	1	1
2017	1	0	1
2019	1	0	1
2023	1	0	1

Below are the most recent publications written about "Positive Transcriptional Elongation Factor B" by people in Profiles.

Roy SD, Nagarajan S, Jalal MS, Basar MA, Duttaroy A. New mutant alleles for Spargel/dPGC-1 highlights the function of Spargel RRM domain in oogenesis and expands the role of Spargel in embryogenesis and intracellular transport. G3 (Bethesda). 2023 08 30; 13(9).

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Basar MA, Williamson K, Roy SD, Finger DS, Ables ET, Duttaroy A. Spargel/dPGC-1 is essential for oogenesis and nutrient-mediated ovarian growth in Drosophila. Dev Biol. 2019 10 15; 454(2):97-107.

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Shii L, Song L, Maurer K, Zhang Z, Sullivan KE. SERPINB2 is regulated by dynamic interactions with pause-release proteins and enhancer RNAs. Mol Immunol. 2017 08; 88:20-31.

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Tyagi M, Iordanskiy S, Ammosova T, Kumari N, Smith K, Breuer D, Ilatovskiy AV, Kont YS, Ivanov A, ?ren A, Kovalskyy D, Petukhov M, Kashanchi F, Nekhai S. Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1. Retrovirology. 2015 Jul 16; 12:63.

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Mukherjee S, Duttaroy A. Spargel/dPGC-1 is a new downstream effector in the insulin-TOR signaling pathway in Drosophila. Genetics. 2013 Oct; 195(2):433-41.

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Adamik J, Wang KZ, Unlu S, Su AJ, Tannahill GM, Galson DL, O'Neill LA, Auron PE. Distinct mechanisms for induction and tolerance regulate the immediate early genes encoding interleukin 1? and tumor necrosis factor a. PLoS One. 2013; 8(8):e70622.

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Breuer D, Kotelkin A, Ammosova T, Kumari N, Ivanov A, Ilatovskiy AV, Beullens M, Roane PR, Bollen M, Petukhov MG, Kashanchi F, Nekhai S. CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90. Retrovirology. 2012 Nov 09; 9:94.

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Cheng Y, Jin Z, Agarwal R, Ma K, Yang J, Ibrahim S, Olaru AV, David S, Ashktorab H, Smoot DT, Duncan MD, Hutcheon DF, Abraham JM, Meltzer SJ, Mori Y. LARP7 is a potential tumor suppressor gene in gastric cancer. Lab Invest. 2012 Jul; 92(7):1013-9.

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Espinoza-Derout J, Wagner M, Shahmiri K, Mascareno E, Chaqour B, Siddiqui MA. Pivotal role of cardiac lineage protein-1 (CLP-1) in transcriptional elongation factor P-TEFb complex formation in cardiac hypertrophy. Cardiovasc Res. 2007 Jul 01; 75(1):129-38.

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Nekhai S, Zhou M, Fernandez A, Lane WS, Lamb NJ, Brady J, Kumar A. HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcription. Biochem J. 2002 Jun 15; 364(Pt 3):649-57.

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