"Colchicine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE).
Descriptor ID |
D003078
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MeSH Number(s) |
D03.132.225
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Colchicine".
Below are MeSH descriptors whose meaning is more specific than "Colchicine".
This graph shows the total number of publications written about "Colchicine" by people in this website by year, and whether "Colchicine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
2003 | 0 | 2 | 2 |
2008 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Colchicine" by people in Profiles.
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Gago R, Vil? S, V?lez-Rivera J, Vil? LM. Severe systemic inflammatory response syndrome immediately after spinal surgery in a patient with axial gout. BMJ Case Rep. 2018 Jan 24; 2018.
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Jim?nez C, Ellahioui Y, ?lvarez R, Aramburu L, Riesco A, Gonz?lez M, Vicente A, Dahdouh A, Ibn Mansour A, Jim?nez C, Mart?n D, Sarmiento RG, Medarde M, Caballero E, Pel?ez R. Exploring the size adaptability of the B ring binding zone of the?colchicine site of tubulin with para-nitrogen substituted isocombretastatins. Eur J Med Chem. 2015 Jul 15; 100:210-22.
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Zheng S, Zhong Q, Mottamal M, Zhang Q, Zhang C, Lemelle E, McFerrin H, Wang G. Design, synthesis, and biological evaluation of novel pyridine-bridged analogues of combretastatin-A4 as anticancer agents. J Med Chem. 2014 Apr 24; 57(8):3369-81.
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Lynch M, O'Donnell R, Weintraub NL, L?pez-Candales A. Assessment of mitral annular and velocity vector imaging in acute myopericarditis. Echocardiography. 2013 Sep; 30(8):E227-30.
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Gonzalez-Cadavid NF, Rajfer J. Experimental models of Peyronie's disease. Implications for new therapies. J Sex Med. 2009 Feb; 6(2):303-13.
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DeMaio L, Tarbell JM, Scaduto RC, Gardner TW, Antonetti DA. A transmural pressure gradient induces mechanical and biological adaptive responses in endothelial cells. Am J Physiol Heart Circ Physiol. 2004 Feb; 286(2):H731-41.
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Okere CO, Waterhouse BD. Inter- and intra-nuclear differences in galanin expression between the hypothalamic paraventricular and supraoptic nuclei in colchicine-untreated rats. Brain Res. 2003 May 16; 972(1-2):222-8.
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Phelix CF, Liposits Z, Paull WK. Catecholamine-CRF synaptic interaction in a septal bed nucleus: afferents of neurons in the bed nucleus of the stria terminalis. Brain Res Bull. 1994; 33(1):109-19.
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Ochieng J, Tait L, Russo J. Calcium-mediated modulation of microtubule assembly in human breast epithelial cells. In Vitro Cell Dev Biol. 1990 Apr; 26(4):318-24.
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Phelix CF, Paull WK. Demonstration of distinct corticotropin releasing factor--containing neuron populations in the bed nucleus of the stria terminalis. A light and electron microscopic immunocytochemical study in the rat. Histochemistry. 1990; 94(4):345-64.