"Swainsonine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity.
| Descriptor ID |
D017026
|
| MeSH Number(s) |
D03.132.830
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Swainsonine".
Below are MeSH descriptors whose meaning is more specific than "Swainsonine".
This graph shows the total number of publications written about "Swainsonine" by people in this website by year, and whether "Swainsonine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
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Below are the most recent publications written about "Swainsonine" by people in Profiles.
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Zhao H, Hans S, Cheng X, Mootoo DR. Allylated monosaccharides as precursors in triple reductive amination strategies: synthesis of castanospermine and swainsonine. J Org Chem. 2001 Mar 09; 66(5):1761-7.
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Mohla S, White S, Grzegorzewski K, Nielsen D, Dunston G, Dickson L, Cha JK, Asseffa A, Olden K. Inhibition of growth of subcutaneous xenografts and metastasis of human breast carcinoma by swainsonine: modulation of tumor cell HLA class I antigens and host immune effector mechanisms. Anticancer Res. 1990 Nov-Dec; 10(6):1515-22.
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Chambers JP, Tsin AT, Raymond NY, Aldape FG, Rodriguez KA. Effects of glycosylation inhibitors on the frog retina. Brain Res Bull. 1986 Aug; 17(2):259-63.