"Acetogenins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Polyketides of up to a few dozen carbons in length, formed by chain extension of multiple PROPIONATES and oxygenated to form tetrahydrofuran and lactone rings along the length of the chain. They are found in ANNONACEAE and other PLANTS. Related compounds cyclize to MACROLIDES.
| Descriptor ID |
D054378
|
| MeSH Number(s) |
D02.033.415.054 D02.455.326.146.049 D02.540.205 D03.383.312.200 D10.289.054
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Acetogenins".
Below are MeSH descriptors whose meaning is more specific than "Acetogenins".
This graph shows the total number of publications written about "Acetogenins" by people in this website by year, and whether "Acetogenins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Acetogenins" by people in Profiles.
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Periche PG, Lin J, Bhupathiraju NVSDK, Kalidindi T, Johnson DS, Pillarsetty N, Mootoo DR. Targeting Carbohydrate Mimetics of Tetrahydrofuran-Containing Acetogenins to Prostate Cancer. Molecules. 2023 Mar 23; 28(7).
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Gonzalez Periche P, Ramdular A, Bhupathiraju NVSDK, Kalidindi T, Johnson DS, Pillarsetty N, Mootoo DR. Synthesis of carbohydrate analogues of the THF-acetogenin 4-deoxyannomontacin and their cytotoxicity against human prostate cancer cell lines. Carbohydr Res. 2022 Nov; 521:108671.
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Bachan S, Tony KA, Kawamura A, Montenegro D, Joshi A, Garg H, Mootoo DR. Synthesis and anti-tumor activity of carbohydrate analogues of the tetrahydrofuran containing acetogenins. Bioorg Med Chem. 2013 Nov 01; 21(21):6554-64.
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Wang F, Kawamura A, Mootoo DR. Synthesis and antitumor activity of C-9 epimers of the tetrahydrofuran containing acetogenin 4-deoxyannoreticuin. Bioorg Med Chem. 2008 Sep 15; 16(18):8413-8.
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Zhu L, Mootoo DR. Total synthesis of the nonadjacently linked bis-tetrahydrofuran acetogenin bullatanocin (squamostatin C). J Org Chem. 2004 Apr 30; 69(9):3154-7.