"Pilocarpine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
| Descriptor ID |
D010862
|
| MeSH Number(s) |
D03.132.672
|
| Concept/Terms |
Pilocarpine Nitrate- Pilocarpine Nitrate
- Nitrate, Pilocarpine
- Pilocarpine Mononitrate, (3S-cis)-Isomer
|
Below are MeSH descriptors whose meaning is more general than "Pilocarpine".
Below are MeSH descriptors whose meaning is more specific than "Pilocarpine".
This graph shows the total number of publications written about "Pilocarpine" by people in this website by year, and whether "Pilocarpine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pilocarpine" by people in Profiles.
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Owen B, Bichler E, Benveniste M. Excitatory synaptic transmission in hippocampal area CA1 is enhanced then reduced as chronic epilepsy progresses. Neurobiol Dis. 2021 07; 154:105343.
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Carpenter-Hyland E, Bichler EK, Smith M, Sloviter RS, Benveniste M. Epileptic pilocarpine-treated rats exhibit aberrant hippocampal EPSP-spike potentiation but retain long-term potentiation. Physiol Rep. 2017 Nov; 5(21).
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Edelstein J, Hao T, Cao Q, Morales L, Rockwell P. Crosstalk between VEGFR2 and muscarinic receptors regulates the mTOR pathway in serum starved SK-N-SH human neuroblastoma cells. Cell Signal. 2011 Jan; 23(1):239-48.
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Benveniste M, Wilhelm J, Dingledine RJ, Mott DD. Subunit-dependent modulation of kainate receptors by muscarinic acetylcholine receptors. Brain Res. 2010 Sep 17; 1352:61-9.
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Chen Z, Chen S, Chen L, Zhou J, Dai Q, Yang L, Li X, Zhou L. Long-term increasing co-localization of SCN8A and ankyrin-G in rat hippocampal cornu ammonis 1 after pilocarpine induced status epilepticus. Brain Res. 2009 May 13; 1270:112-20.
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Rasmussen BA, Perry DC, O'Neil J, Manaye KF, Tizabi Y. Effects of nicotine on sensorimotor gating impairment induced by long-term treatment with neurotoxic NMDA antagonism. Neurotox Res. 2008 May-Jun; 13(3-4):151-61.
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Mej?as-Aponte CA, Jim?nez-Rivera CA, Segarra AC. Sex differences in models of temporal lobe epilepsy: role of testosterone. Brain Res. 2002 Jul 19; 944(1-2):210-8.