Ventral Tegmental Area

"Ventral Tegmental Area" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A region in the MESENCEPHALON which is dorsomedial to the SUBSTANTIA NIGRA and ventral to the RED NUCLEUS. The mesocortical and mesolimbic dopaminergic systems originate here, including an important projection to the NUCLEUS ACCUMBENS. Overactivity of the cells in this area has been suspected to contribute to the positive symptoms of SCHIZOPHRENIA.

Descriptor ID	D017557
MeSH Number(s)	A08.186.211.132.659.413.875.820
Concept/Terms	Ventral Tegmental Area Ventral Tegmental Area Tegmental Area, Ventral Ventral Tegmental Area of Tsai Area Tegmentalis Ventralis Area Tegmentalis Ventrali Tegmentalis Ventrali, Area Tegmentalis Ventralis, Area

Below are MeSH descriptors whose meaning is more general than "Ventral Tegmental Area".

Anatomy [A]
Nervous System [A08]
Central Nervous System [A08.186]
Brain [A08.186.211]
Brain Stem [A08.186.211.132]
Mesencephalon [A08.186.211.132.659]
Cerebral Peduncle [A08.186.211.132.659.413]
Tegmentum Mesencephali [A08.186.211.132.659.413.875]
Ventral Tegmental Area [A08.186.211.132.659.413.875.820]

Below are MeSH descriptors whose meaning is related to "Ventral Tegmental Area".

Below are MeSH descriptors whose meaning is more specific than "Ventral Tegmental Area".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ventral Tegmental Area" by people in this website by year, and whether "Ventral Tegmental Area" was a major or minor topic of these publications.

Bar chart showing 42 publications over 23 distinct years, with a maximum of 4 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
2001	0	1	1
2002	1	2	3
2003	0	1	1
2004	2	0	2
2005	1	0	1
2007	2	1	3
2008	2	1	3
2009	0	1	1
2010	2	0	2
2011	3	0	3
2012	3	0	3
2013	0	1	1
2014	2	0	2
2015	0	1	1
2016	1	0	1
2017	0	2	2
2018	1	0	1
2019	3	1	4
2020	1	1	2
2021	1	0	1
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Ventral Tegmental Area" by people in Profiles.

Luj?n M?, Covey DP, Young-Morrison R, Zhang L, Kim A, Morgado F, Patel S, Bass CE, Paladini C, Cheer JF. Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction. Nat Commun. 2023 11 20; 14(1):7545.

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Clauss N, Allen KB, Billings KD, Tolliver MDM, Garza R, Byrd-Craven J, Campbell P. The Modification of Offspring Stress-Related Behavior and the Expression of Drd1, Drd2, and Nr3c1 by a Western-Pattern Diet in Mus Musculus. Int J Mol Sci. 2022 Aug 17; 23(16).

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Bosque-Cordero KY, Vazquez-Torres R, Calo-Guadalupe C, Consuegra-Garcia D, Fois GR, Georges F, Jimenez-Rivera CA. Ih blockade reduces cocaine-induced firing patterns of putative dopaminergic neurons of the ventral tegmental area in the anesthetized rat. Prog Neuropsychopharmacol Biol Psychiatry. 2022 01 10; 112:110431.

View in: PubMed
Cruz B, Carcoba LM, Flores RJ, Espinoza EJ, Nazarian A, O'Dell LE. Insulin restores the neurochemical effects of nicotine in the mesolimbic pathway of diabetic rats. J Neurochem. 2021 01; 156(2):200-211.

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Mohandass A, Krishnan V, Gribkova ED, Asuthkar S, Baskaran P, Nersesyan Y, Hussain Z, Wise LM, George RE, Stokes N, Alexander BM, Cohen AM, Pavlov EV, Llano DA, Zhu MX, Thyagarajan B, Zakharian E. TRPM8 as the rapid testosterone signaling receptor: Implications in the regulation of dimorphic sexual and social behaviors. FASEB J. 2020 08; 34(8):10887-10906.

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Gomez JA, Perkins JM, Beaudoin GM, Cook NB, Quraishi SA, Szoeke EA, Thangamani K, Tschumi CW, Wanat MJ, Maroof AM, Beckstead MJ, Rosenberg PA, Paladini CA. Ventral tegmental area astrocytes orchestrate avoidance and approach behavior. Nat Commun. 2019 03 29; 10(1):1455.

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Opendak M, Robinson-Drummer P, Blomkvist A, Zanca RM, Wood K, Jacobs L, Chan S, Tan S, Woo J, Venkataraman G, Kirschner E, Lundstr?m JN, Wilson DA, Serrano PA, Sullivan RM. Neurobiology of maternal regulation of infant fear: the role of mesolimbic dopamine and its disruption by maltreatment. Neuropsychopharmacology. 2019 06; 44(7):1247-1257.

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Wang HL, Zhang S, Qi J, Wang H, Cachope R, Mejias-Aponte CA, Gomez JA, Mateo-Semidey GE, Beaudoin GMJ, Paladini CA, Cheer JF, Morales M. Dorsal Raphe Dual Serotonin-Glutamate Neurons Drive Reward by Establishing Excitatory Synapses on VTA Mesoaccumbens Dopamine Neurons. Cell Rep. 2019 01 29; 26(5):1128-1142.e7.

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Cruz B, Flores RJ, Uribe KP, Espinoza EJ, Spencer CT, Serafine KM, Nazarian A, O'Dell LE. Insulin modulates the strong reinforcing effects of nicotine and changes in insulin biomarkers in a rodent model of diabetes. Neuropsychopharmacology. 2019 05; 44(6):1141-1151.

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Vaquer-Alicea ADC, V?zquez-Torres R, Devarie-Hornedo M, Vicenty-Padilla JC, Santos-Vera B, Mar?a-R?os C, V?lez-Hern?ndez ME, Sacktor T, Jim?nez-Rivera CA. aPKC-Mediated Persistent Increase in AMPA/NMDA Ratio in the VTA Participates in the Neuroadaptive Signal Necessary to Induce NAc Synaptic Plasticity After Cocaine Administration. Neuroscience. 2018 11 10; 392:129-140.

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