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Rosa E. Blanco

TitlePhD
Faculty RankProfessor
InstitutionUniversity of Puerto Rico
DepartmentSchool of Medicine
AddressUPR-Medical Sciences Campus, School of Medicine
San Juan PR 936
Phone7877241962
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    My research interest are concerned with the interactions between neurons and glial cells that determine the survival of injured retinal ganglion cells, and understanding the role that growth factors play on the recovery and plasticity of the visual system. I am also interested in the specificity of the synaptic connections between neurons during development and regeneration.

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kim S, Ochoa K, Melli SE, Yousufzai FAK, Barrera ZD, Williams AA, McIntyre G, Delgado E, Bolish JN, Macleod CM, Boghos M, Lens HP, Ramos AG, Wilson VB, Maloney K, Padron ZM, Khan AH, Blanco RE, Soto I. Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease. Sci Rep. 2023 04 06; 13(1):5665. PMID: 37024714.
      Citations: 6     Fields:    Translation:AnimalsCells
    2. De La Rosa-Reyes V, Duprey-D?az MV, Blagburn JM, Blanco RE. Retinoic acid treatment recruits macrophages and increases axonal regeneration after optic nerve injury in the frog Rana pipiens. PLoS One. 2021; 16(11):e0255196. PMID: 34739478.
      Citations: 3     Fields:    Translation:AnimalsCells
    3. Kavetsky L, Green KK, Boyle BR, Yousufzai FAK, Padron ZM, Melli SE, Kuhnel VL, Jackson HM, Blanco RE, Howell GR, Soto I. Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C. Sci Rep. 2019 10 11; 9(1):14722. PMID: 31605022.
      Citations: 18     Fields:    Translation:AnimalsCells
    4. Blanco RE, Vega-Mel?ndez GS, De La Rosa-Reyes V, Del Cueto C, Blagburn JM. Application of CNTF or FGF-2 increases the number of M2-like macrophages after optic nerve injury in adult Rana pipiens. PLoS One. 2019; 14(5):e0209733. PMID: 31048836.
      Citations: 11     Fields:    Translation:AnimalsCells
    5. Duprey-D?az MV, Blagburn JM, Blanco RE. Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System after Optic Nerve Injury. PLoS One. 2016; 11(9):e0162626. PMID: 27611191.
      Citations: 12     Fields:    Translation:AnimalsCells
    6. Duprey-D?az MV, Blagburn JM, Blanco RE. Optic nerve injury upregulates retinoic acid signaling in the adult frog visual system. J Chem Neuroanat. 2016 11; 77:80-92. PMID: 27242163.
      Citations: 8     Fields:    Translation:AnimalsCells
    7. Vega-Mel?ndez GS, Blagburn JM, Blanco RE. Ciliary neurotrophic factor and fibroblast growth factor increase the speed and number of regenerating axons after optic nerve injury in adult Rana pipiens. J Neurosci Res. 2014 Jan; 92(1):13-23. PMID: 24166589.
      Citations: 9     Fields:    Translation:AnimalsCells
    8. Duprey-D?az MV, Blagburn JM, Blanco RE. Changes in fibroblast growth factor-2 and FGF receptors in the frog visual system during optic nerve regeneration. J Chem Neuroanat. 2012 Dec; 46(1-2):35-44. PMID: 22940608.
      Citations: 5     Fields:    Translation:Animals
    9. Blanco RE, Soto I, Duprey-D?az M, Blagburn JM. Up-regulation of brain-derived neurotrophic factor by application of fibroblast growth factor-2 to the cut optic nerve is important for long-term survival of retinal ganglion cells. J Neurosci Res. 2008 Nov 15; 86(15):3382-92. PMID: 18655198.
      Citations: 12     Fields:    Translation:AnimalsCells
    10. Soto I, L?pez-Roca T, Blagburn JM, Blanco RE. Changes in nNOS and NADPH diaphorase in frog retina and tectum after axotomy and FGF-2 application. Brain Res. 2006 Aug 04; 1103(1):65-75. PMID: 16808907.
      Citations: 4     Fields:    Translation:AnimalsCells
    11. Soto I, Rosenthal JJ, Blagburn JM, Blanco RE. Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways. J Neurochem. 2006 Jan; 96(1):82-96. PMID: 16269011.
      Citations: 24     Fields:    Translation:AnimalsCells
    12. R?os-Mu?oz W, Soto I, Duprey-D?az MV, Blagburn J, Blanco RE. Fibroblast growth factor 2 applied to the optic nerve after axotomy increases Bcl-2 and decreases Bax in ganglion cells by activating the extracellular signal-regulated kinase signaling pathway. J Neurochem. 2005 Jun; 93(6):1422-33. PMID: 15935058.
      Citations: 12     Fields:    Translation:AnimalsCells
    13. Duprey-D?az MV, Blagburn JM, Blanco RE. Neurotrophin-3 and TrkC in the frog visual system: changes after axotomy. Brain Res. 2003 Aug 22; 982(1):54-63. PMID: 12915240.
      Citations: 2     Fields:    Translation:AnimalsCells
    14. Soto I, Marie B, Baro DJ, Blanco RE. FGF-2 modulates expression and distribution of GAP-43 in frog retinal ganglion cells after optic nerve injury. J Neurosci Res. 2003 Aug 15; 73(4):507-17. PMID: 12898535.
      Citations: 9     Fields:    Translation:AnimalsCells
    15. Duprey-D?az MV, Soto I, Blagburn JM, Blanco RE. Changes in brain-derived neurotrophic factor and trkB receptor in the adult Rana pipiens retina and optic tectum after optic nerve injury. J Comp Neurol. 2002 Dec 23; 454(4):456-69. PMID: 12455009.
      Citations: 9     Fields:    Translation:Animals
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