Receptors, Platelet-Derived Growth Factor
"Receptors, Platelet-Derived Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.
| Descriptor ID |
D017479
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.900 D12.776.543.750.630.625 D12.776.543.750.750.400.630
|
| Concept/Terms |
Receptors, Platelet-Derived Growth Factor- Receptors, Platelet-Derived Growth Factor
- Receptors, Platelet Derived Growth Factor
- Platelet-Derived Growth Factor Receptors
- Platelet Derived Growth Factor Receptors
- Receptors, PDGF
- PDGF Receptor
- Receptor, PDGF
- PDGF Receptors
- Platelet-Derived Growth Factor Receptor
- Platelet Derived Growth Factor Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Platelet-Derived Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Platelet-Derived Growth Factor".
This graph shows the total number of publications written about "Receptors, Platelet-Derived Growth Factor" by people in this website by year, and whether "Receptors, Platelet-Derived Growth Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Platelet-Derived Growth Factor" by people in Profiles.
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Smith CL, Tallquist MD. PDGF function in diverse neural crest cell populations. Cell Adh Migr. 2010 Oct-Dec; 4(4):561-6.
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Richarte AM, Mead HB, Tallquist MD. Cooperation between the PDGF receptors in cardiac neural crest cell migration. Dev Biol. 2007 Jun 15; 306(2):785-96.
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Liu D, Hou J, Hu X, Wang X, Xiao Y, Mou Y, De Leon H. Neuronal chemorepellent Slit2 inhibits vascular smooth muscle cell migration by suppressing small GTPase Rac1 activation. Circ Res. 2006 Mar 03; 98(4):480-9.
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Fielding PE, Chau P, Liu D, Spencer TA, Fielding CJ. Mechanism of platelet-derived growth factor-dependent caveolin-1 phosphorylation: relationship to sterol binding and the role of serine-80. Biochemistry. 2004 Mar 09; 43(9):2578-86.
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Andrews A, Balciunaite E, Leong FL, Tallquist M, Soriano P, Refojo M, Kazlauskas A. Platelet-derived growth factor plays a key role in proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 1999 Oct; 40(11):2683-9.
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Heuchel R, Berg A, Tallquist M, Ahl?n K, Reed RK, Rubin K, Claesson-Welsh L, Heldin CH, Soriano P. Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling. Proc Natl Acad Sci U S A. 1999 Sep 28; 96(20):11410-5.