Spectrometry, Mass, Secondary Ion
"Spectrometry, Mass, Secondary Ion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass-spectrometric technique that is used for microscopic chemical analysis. A beam of primary ions with an energy of 5-20 kiloelectronvolts (keV) bombards a small spot on the surface of the sample under ultra-high vacuum conditions. Positive and negative secondary ions sputtered from the surface are analyzed in a mass spectrometer in regards to their mass-to-charge ratio. Digital imaging can be generated from the secondary ion beams and their intensity can be measured. Ionic images can be correlated with images from light or other microscopy providing useful tools in the study of molecular and drug actions.
| Descriptor ID |
D018629
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| MeSH Number(s) |
E05.196.566.760
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| Concept/Terms |
Spectrometry, Mass, Secondary Ion- Spectrometry, Mass, Secondary Ion
- Secondary Ion Mass Spectroscopy Microscopy
- Mass Spectrometry, Secondary Ion
- Secondary Ion Mass Spectrometry
- SIMS Microscopy
- Secondary Ion Mass Spectroscopy
- Mass Spectroscopy, Secondary Ion
- Spectroscopy, Mass, Secondary Ion
- Secondary Ion Mass Spectrometry Microscopy
|
Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Secondary Ion".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Secondary Ion".
This graph shows the total number of publications written about "Spectrometry, Mass, Secondary Ion" by people in this website by year, and whether "Spectrometry, Mass, Secondary Ion" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spectrometry, Mass, Secondary Ion" by people in Profiles.
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Sparvero LJ, Tian H, Amoscato AA, Sun WY, Anthonymuthu TS, Tyurina YY, Kapralov O, Javadov S, He RR, Watkins SC, Winograd N, Kagan VE, Bayir H. Direct Mapping of Phospholipid Ferroptotic Death Signals in Cells and Tissues by Gas Cluster Ion Beam Secondary Ion Mass Spectrometry (GCIB-SIMS). Angew Chem Int Ed Engl. 2021 05 17; 60(21):11784-11788.
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Cohen SK, Aschtgen MS, Lynch JB, Koehler S, Chen F, Escrig S, Daraspe J, Ruby EG, Meibom A, McFall-Ngai M. Tracking the cargo of extracellular symbionts into host tissues with correlated electron microscopy and nanoscale secondary ion mass spectrometry imaging. Cell Microbiol. 2020 04; 22(4):e13177.