Mice, Transgenic

"Mice, Transgenic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.

Descriptor ID	D008822
MeSH Number(s)	B01.050.050.136.500 B01.050.150.900.649.313.992.635.505.500.800
Concept/Terms	Mice, Transgenic Mice, Transgenic Mouse, Transgenic Transgenic Mouse Transgenic Mice Founder Mice, Transgenic Founder Mice, Transgenic Mice, Transgenic Founder Transgenic Founder Mice Mouse, Founder, Transgenic

Below are MeSH descriptors whose meaning is more general than "Mice, Transgenic".

Organisms [B]
Eukaryota [B01]
Animals [B01.050]
Animal Population Groups [B01.050.050]
Animals, Genetically Modified [B01.050.050.136]
Mice, Transgenic [B01.050.050.136.500]
Chordata [B01.050.150]
Vertebrates [B01.050.150.900]
Mammals [B01.050.150.900.649]
Eutheria [B01.050.150.900.649.313]
Rodentia [B01.050.150.900.649.313.992]
Muridae [B01.050.150.900.649.313.992.635]
Murinae [B01.050.150.900.649.313.992.635.505]
Mice [B01.050.150.900.649.313.992.635.505.500]
Mice, Transgenic [B01.050.150.900.649.313.992.635.505.500.800]

Below are MeSH descriptors whose meaning is related to "Mice, Transgenic".

Below are MeSH descriptors whose meaning is more specific than "Mice, Transgenic".

Mice, Transgenic
Mice, Knockout

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mice, Transgenic" by people in this website by year, and whether "Mice, Transgenic" was a major or minor topic of these publications.

Bar chart showing 535 publications over 30 distinct years, with a maximum of 30 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	4	4
1997	1	1	2
1998	1	9	10
1999	0	3	3
2000	0	7	7
2001	0	11	11
2002	1	24	25
2003	0	19	19
2004	0	24	24
2005	0	22	22
2006	0	25	25
2007	2	20	22
2008	0	28	28
2009	0	30	30
2010	0	28	28
2011	0	28	28
2012	1	15	16
2013	0	27	27
2014	0	15	15
2015	1	23	24
2016	0	21	21
2017	1	21	22
2018	0	24	24
2019	1	23	24
2020	0	18	18
2021	0	15	15
2022	0	11	11
2023	0	6	6
2024	7	6	13
2025	0	11	11

Below are the most recent publications written about "Mice, Transgenic" by people in Profiles.

Hon A, Lu M, Shao XM, Demer LL, Tintut Y. Cardiovascular-specific PTH1R activation enhances exercise-induced cardiac remodeling in a mouse model of calcific atherosclerosis. Biochem Biophys Res Commun. 2026 Jul 09; 821:153870.

View in: PubMed
Elia A, Parodi-Rullan R, Vazquez-Torres R, Carey A, Zhao H, Javadov S, Fossati S. Amyloid ? Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease. Adv Sci (Weinh). 2026 Apr; 13(20):e11924.

View in: PubMed
Garc?a-Carlos CA, Salas-Gallardo A, Gonz?lez-Pereyra P, Basurto-Islas G, Perry G, Mondrag?n-Rodr?guez S. Amyloid-? and phosphorylated-tau accumulation in retrosplenial cortex of young Alzheimer's disease model: Impact on network activity. J Alzheimers Dis. 2026 Mar; 110(2):576-587.

View in: PubMed
Shin HE, An S, Heckl J, Komori C, Sullivan H, Zorilla R, Yoon H, Pedro TK, Tallquist MD, Park J. PDGFRa+ fibroblast ablation exacerbates pathologic features in a model of house dust mite-induced allergenic asthma. Dis Model Mech. 2025 12 01; 18(12).

View in: PubMed
Marshall AG, Stephens D, Neikirk K, Masenga SK, Shao B, Crabtree A, Vue Z, Beasley HK, Garza-Lopez E, Scudese E, Rodriguez BI, Le H, Damo S, Taffet GE, Ochayi OM, McMillan R, Afolabi JM, Exil V, Oliver A, Sharma V, Martin P, Gaye A, Harris C, Tomeau B, Bell L, Hamilton M, Gillyard T, Webster R, Jackson M, Prakash P, Frierson S, Dash C, Mungai M, Kirabo A, Gaddy JA, Wandira N, Hinton A, Reddy AK. Alterations in Cardiovascular Parameters in 5xFAD Murine Model. Cell Biochem Funct. 2025 Nov; 43(11):e70138.

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Reed SL, Aiani LM, Faiz E, Adediran E, Benveniste M, Murnane KS, D'Souza M, Escayg A, Wong JC. Nanoparticle-encapsulated neuropeptide Y provides robust seizure protection in SCN1A-derived epilepsy. Epilepsia. 2026 Jan; 67(1):424-436.

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Garc?a-Carlos CA, Basurto-Islas G, Perry G, Campos-Ram?rez C, Mondrag?n-Rodr?guez S. Hyperphosphorylated Tau Induces Cortical Hypoexcitability in Transgenic Mouse Models: A Meta-Analysis. J Integr Neurosci. 2025 Aug 28; 24(8):39192.

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Gawande DY, Murali SV, Thakur SS, Rahmatulloev S, Nicolaisen EJ, Batalkina L, Cardona AE, Kaur T. Genetic polymorphisms in human CX3CR1-mediated macrophage dysregulation are associated with the worsening of hearing loss and cochlear degeneration after noise trauma: a study in a humanized mouse model. J Neuroinflammation. 2025 Aug 16; 22(1):204.

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Martinez-Perez DA, McGlothan JL, Rodichkin AN, Abilmouna K, Bursac Z, Lopera F, Villegas-Lanau CA, Guilarte TR. Amyloid-? plaque-associated microglia drive TSPO upregulation in Alzheimer's disease. Acta Neuropathol. 2025 Jul 17; 150(1):6.

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Ofosu-Boateng M, Choi S, Kim S, Twum E, Nnamani DO, Gebreyesus LH, Niture S, Yadak N, Kumar D, Gonzalez FJ, Liangpunsakul S, Cui JY, Gyamfi MA. Human PXR Signaling Exacerbates Ethanol-induced Liver Injury in Females: Evidence From Mouse Models and Human Alcohol-associated Liver Disease Cohorts. Cell Mol Gastroenterol Hepatol. 2025; 19(11):101589.

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