Rats, Transgenic

"Rats, Transgenic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Laboratory rats that have been produced from a genetically manipulated rat EGG or rat EMBRYO, MAMMALIAN. They contain genes from another species.

Descriptor ID	D055647
MeSH Number(s)	B01.050.050.136.700 B01.050.150.900.649.313.992.635.505.700.825
Concept/Terms	Rats, Transgenic Rats, Transgenic Transgenic Rat Rat, Transgenic Transgenic Rats

Below are MeSH descriptors whose meaning is more general than "Rats, Transgenic".

Organisms [B]
Eukaryota [B01]
Animals [B01.050]
Animal Population Groups [B01.050.050]
Animals, Genetically Modified [B01.050.050.136]
Rats, Transgenic [B01.050.050.136.700]
Chordata [B01.050.150]
Vertebrates [B01.050.150.900]
Mammals [B01.050.150.900.649]
Eutheria [B01.050.150.900.649.313]
Rodentia [B01.050.150.900.649.313.992]
Muridae [B01.050.150.900.649.313.992.635]
Murinae [B01.050.150.900.649.313.992.635.505]
Rats [B01.050.150.900.649.313.992.635.505.700]
Rats, Transgenic [B01.050.150.900.649.313.992.635.505.700.825]

Below are MeSH descriptors whose meaning is related to "Rats, Transgenic".

Below are MeSH descriptors whose meaning is more specific than "Rats, Transgenic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Rats, Transgenic" by people in this website by year, and whether "Rats, Transgenic" was a major or minor topic of these publications.

Bar chart showing 18 publications over 12 distinct years, with a maximum of 3 publications in 2013 and 2014

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2007	1	1
2011	1	1
2012	1	1
2013	3	3
2014	3	3
2015	2	2
2016	1	1
2017	1	1
2019	1	1
2022	2	2
2023	1	1
2024	1	1

Below are the most recent publications written about "Rats, Transgenic" by people in Profiles.

Wallace CH, Oliveros G, Xie L, Serrano P, Rockwell P, Figueiredo-Pereira M. Potential Alzheimer's early biomarkers in a transgenic rat model and benefits of diazoxide/dibenzoylmethane co-treatment on spatial memory and AD-pathology. Sci Rep. 2024 02 14; 14(1):3730.

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Oliveros G, Wallace CH, Chaudry O, Liu Q, Qiu Y, Xie L, Rockwell P, Figueiredo-Pereira ME, Serrano PA. Repurposing ibudilast to mitigate Alzheimer's disease by targeting inflammation. Brain. 2023 03 01; 146(3):898-911.

View in: PubMed
Chaudry O, Ndukwe K, Xie L, Figueiredo-Pereira M, Serrano P, Rockwell P. Females exhibit higher GluA2 levels and outperform males in active place avoidance despite increased amyloid plaques in TgF344-Alzheimer's rats. Sci Rep. 2022 11 09; 12(1):19129.

View in: PubMed
Wallace CH, Oliveros G, Serrano PA, Rockwell P, Xie L, Figueiredo-Pereira M. Timapiprant, a prostaglandin D2 receptor antagonist, ameliorates pathology in a rat Alzheimer's model. Life Sci Alliance. 2022 09 27; 5(12).

View in: PubMed
Shah S, Maric D, Denaro F, Ibrahim W, Mason R, Kumar A, Hammoud DA, Reid W. Nitrosative Stress Is Associated with Dopaminergic Dysfunction in the HIV-1 Transgenic Rat. Am J Pathol. 2019 07; 189(7):1375-1385.

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Zhou Y, Castonguay P, Sidhom EH, Clark AR, Dvela-Levitt M, Kim S, Sieber J, Wieder N, Jung JY, Andreeva S, Reichardt J, Dubois F, Hoffmann SC, Basgen JM, Montesinos MS, Weins A, Johnson AC, Lander ES, Garrett MR, Hopkins CR, Greka A. A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models. Science. 2017 12 08; 358(6368):1332-1336.

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Reid WC, Ibrahim WG, Kim SJ, Denaro F, Casas R, Lee DE, Maric D, Hammoud DA. Characterization of neuropathology in the HIV-1 transgenic rat at different ages. J Neuroimmunol. 2016 Mar 15; 292:116-25.

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Banerjee A, Abdelmegeed MA, Jang S, Song BJ. Increased Sensitivity to Binge Alcohol-Induced Gut Leakiness and Inflammatory Liver Disease in HIV Transgenic Rats. PLoS One. 2015; 10(10):e0140498.

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Li Q, Xu W, Cui Y, Ma L, Richards J, Li W, Ma Y, Fu G, Bythwood T, Wang Y, Li X, Song Q. A preliminary exploration on DNA methylation of transgene across generations in transgenic rats. Sci Rep. 2015 Feb 06; 5:8292.

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Davinelli S, Scapagnini G, Denaro F, Calabrese V, Benedetti F, Krishnan S, Curreli S, Bryant J, Zella D. Altered expression pattern of Nrf2/HO-1 axis during accelerated-senescence in HIV-1 transgenic rat. Biogerontology. 2014; 15(5):449-61.

View in: PubMed

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