"Blood-Brain Barrier" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.
| Descriptor ID |
D001812
|
| MeSH Number(s) |
A07.035 A08.186.211.035
|
| Concept/Terms |
Blood-Brain Barrier- Blood-Brain Barrier
- Barrier, Blood-Brain
- Barriers, Blood-Brain
- Blood Brain Barrier
- Blood-Brain Barriers
- Hemato-Encephalic Barrier
- Barrier, Hemato-Encephalic
- Barriers, Hemato-Encephalic
- Hemato Encephalic Barrier
- Hemato-Encephalic Barriers
- Brain-Blood Barrier
- Barrier, Brain-Blood
- Barriers, Brain-Blood
- Brain Blood Barrier
- Brain-Blood Barriers
|
Below are MeSH descriptors whose meaning is more general than "Blood-Brain Barrier".
Below are MeSH descriptors whose meaning is more specific than "Blood-Brain Barrier".
This graph shows the total number of publications written about "Blood-Brain Barrier" by people in this website by year, and whether "Blood-Brain Barrier" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 2 | 3 |
| 2003 | 3 | 2 | 5 |
| 2004 | 0 | 2 | 2 |
| 2005 | 3 | 5 | 8 |
| 2006 | 1 | 3 | 4 |
| 2007 | 2 | 2 | 4 |
| 2008 | 1 | 4 | 5 |
| 2009 | 3 | 3 | 6 |
| 2010 | 3 | 4 | 7 |
| 2011 | 4 | 5 | 9 |
| 2012 | 2 | 3 | 5 |
| 2013 | 3 | 3 | 6 |
| 2014 | 2 | 4 | 6 |
| 2015 | 2 | 2 | 4 |
| 2016 | 5 | 3 | 8 |
| 2017 | 1 | 4 | 5 |
| 2018 | 3 | 5 | 8 |
| 2019 | 6 | 1 | 7 |
| 2020 | 2 | 2 | 4 |
| 2021 | 4 | 3 | 7 |
| 2022 | 3 | 0 | 3 |
| 2023 | 1 | 2 | 3 |
| 2024 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Blood-Brain Barrier" by people in Profiles.
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Zhou AL, Swaminathan SK, Salian VS, Wang L, Curran GL, Min HK, Lowe VJ, Kandimalla KK. Insulin Signaling Differentially Regulates the Trafficking of Insulin and Amyloid Beta Peptides at the Blood-Brain Barrier. Mol Pharm. 2024 May 06; 21(5):2176-2186.
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Nelson D, Thompson KJ, Wang L, Wang Z, Eberts P, Azarin SM, Kalari KR, Kandimalla KK. Pericyte Control of Gene Expression in the Blood-Brain Barrier Endothelium: Implications for Alzheimer's Disease. J Alzheimers Dis. 2024; 99(s2):S281-S297.
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Abbasloo E, Khaksari M, Sanjari M, Kobeissy F, Thomas TC. Carvacrol decreases blood-brain barrier permeability post-diffuse traumatic brain injury in rats. Sci Rep. 2023 Sep 04; 13(1):14546.
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Wang Z, Sharda N, Omtri RS, Li L, Kandimalla KK. Amyloid-Beta Peptides 40 and 42 Employ Distinct Molecular Pathways for Cell Entry and Intracellular Transit at the Blood-Brain Barrier Endothelium. Mol Pharmacol. 2023 Nov; 104(5):203-213.
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Toropova AP, Toropov AA, Roncaglioni A, Benfenati E, Leszczynska D, Leszczynski J. The validation of predictive potential via the system of self-consistent models: the simulation of blood-brain barrier permeation of organic compounds. J Mol Model. 2023 Jun 29; 29(7):218.
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Wang Z, Tang X, Swaminathan SK, Kandimalla KK, Kalari KR. Mapping the dynamics of insulin-responsive pathways in the blood-brain barrier endothelium using time-series transcriptomics data. NPJ Syst Biol Appl. 2022 08 16; 8(1):29.
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Wang L, Wiedmann TS, Kandimalla KK. Modulating insulin signaling and trafficking at the blood-brain barrier endothelium using lipid based nanoemulsions. Int J Pharm. 2022 Jun 25; 622:121823.
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Zhou AL, Sharda N, Sarma VV, Ahlschwede KM, Curran GL, Tang X, Poduslo JF, Kalari KR, Lowe VJ, Kandimalla KK. Age-Dependent Changes in the Plasma and Brain Pharmacokinetics of Amyloid-? Peptides and Insulin. J Alzheimers Dis. 2022; 85(3):1031-1044.
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Ndemazie NB, Inkoom A, Morfaw EF, Smith T, Aghimien M, Ebesoh D, Agyare E. Multi-disciplinary Approach for Drug and Gene Delivery Systems to the Brain. AAPS PharmSciTech. 2021 Dec 03; 23(1):11.
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Rivera-Ortiz J, Pla-Tenorio J, Cruz ML, Colon K, Perez-Morales J, Rodriguez JA, Martinez-Sicari J, Noel RJ. Blockade of beta adrenergic receptors protects the blood brain barrier and reduces systemic pathology caused by HIV-1 Nef protein. PLoS One. 2021; 16(11):e0259446.