Receptor, Platelet-Derived Growth Factor alpha
"Receptor, Platelet-Derived Growth Factor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A PDGF receptor that binds specifically to both PDGF-A chains and PDGF-B chains. It contains a protein-tyrosine kinase activity that is involved in SIGNAL TRANSDUCTION.
| Descriptor ID |
D020796
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.900.500 D12.776.543.750.630.625.300 D12.776.543.750.750.400.630.300
|
| Concept/Terms |
Receptor, Platelet-Derived Growth Factor alpha- Receptor, Platelet-Derived Growth Factor alpha
- Platelet-Derived Growth Factor alpha Receptor
- Platelet Derived Growth Factor alpha Receptor
- Antigens, CD140a
- PDGFRalpha
- PDGF-R-alpha
- Receptor, PDGF alpha
- CD140a Antigen
- Antigen, CD140a
- PDGFR2
- PDGF alpha Receptor
- CD140a Antigens
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Platelet-Derived Growth Factor alpha".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Transferases [D08.811.913]
- Phosphotransferases [D08.811.913.696]
- Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
- Protein Kinases [D08.811.913.696.620.682]
- Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
- Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
- Receptors, Platelet-Derived Growth Factor [D08.811.913.696.620.682.725.400.900]
- Receptor, Platelet-Derived Growth Factor alpha [D08.811.913.696.620.682.725.400.900.500]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
- Receptors, Platelet-Derived Growth Factor [D12.776.543.750.630.625]
- Receptor, Platelet-Derived Growth Factor alpha [D12.776.543.750.630.625.300]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Platelet-Derived Growth Factor [D12.776.543.750.750.400.630]
- Receptor, Platelet-Derived Growth Factor alpha [D12.776.543.750.750.400.630.300]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Platelet-Derived Growth Factor alpha".
This graph shows the total number of publications written about "Receptor, Platelet-Derived Growth Factor alpha" by people in this website by year, and whether "Receptor, Platelet-Derived Growth Factor alpha" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 2 | 0 | 2 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
| 2023 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptor, Platelet-Derived Growth Factor alpha" by people in Profiles.
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Saito R, Chambers JK, Uchida K. The expression of platelet-derived growth factor and its receptor in canine and feline meningiomas. J Vet Med Sci. 2023 Oct 18; 85(10):1057-1062.
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Kuwabara JT, Hara A, Bhutada S, Gojanovich GS, Chen J, Hokutan K, Shettigar V, Lee AY, DeAngelo LP, Heckl JR, Jahansooz JR, Tacdol DK, Ziolo MT, Apte SS, Tallquist MD. Consequences of PDGFRa+ fibroblast reduction in adult murine hearts. Elife. 2022 09 23; 11.
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Kuwabara JT, Hara A, Heckl JR, Pe?a B, Bhutada S, DeMaris R, Ivey MJ, DeAngelo LP, Liu X, Park J, Jahansooz JR, Mestroni L, McKinsey TA, Apte SS, Tallquist MD. Regulation of extracellular matrix composition by fibroblasts during perinatal cardiac maturation. J Mol Cell Cardiol. 2022 08; 169:84-95.
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Ivey MJ, Kuwabara JT, Riggsbee KL, Tallquist MD. Platelet-derived growth factor receptor-a is essential for cardiac fibroblast survival. Am J Physiol Heart Circ Physiol. 2019 08 01; 317(2):H330-H344.
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McCarthy N, Liu JS, Richarte AM, Eskiocak B, Lovely CB, Tallquist MD, Eberhart JK. Pdgfra and Pdgfrb genetically interact during craniofacial development. Dev Dyn. 2016 06; 245(6):641-52.
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Osada M, Singh VJ, Wu K, Sant'Angelo DB, Pezzano M. Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus. PLoS One. 2013; 8(12):e83024.
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Jaworski C, Looi JL, Martin J, Bergin P, Hare J, Kaye D, Wei A, Taylor AJ. Cardiac Imaging in FIP1L1-PDGFRA. J Am Coll Cardiol. 2013 Oct 01; 62(14):1304.
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Baek ST, Tallquist MD. Nf1 limits epicardial derivative expansion by regulating epithelial to mesenchymal transition and proliferation. Development. 2012 Jun; 139(11):2040-9.
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Ma Q, Huang B, Khatibi N, Rolland W, Suzuki H, Zhang JH, Tang J. PDGFR-a inhibition preserves blood-brain barrier after intracerebral hemorrhage. Ann Neurol. 2011 Dec; 70(6):920-31.
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Smith CL, Baek ST, Sung CY, Tallquist MD. Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling. Circ Res. 2011 Jun 10; 108(12):e15-26.