Repressor Proteins

RCMI Coordinating Center (RCMI CC)

"Repressor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.

Descriptor ID	D012097
MeSH Number(s)	D12.776.260.703 D12.776.930.780
Concept/Terms	Repressor Proteins Repressor Proteins Proteins, Repressor Transcriptional Silencing Factors Transcriptional Silencing Factors Silencing Factors, Transcriptional Repressor Molecules Repressor Molecules

Below are MeSH descriptors whose meaning is more general than "Repressor Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Repressor Proteins [D12.776.260.703]
Transcription Factors [D12.776.930]
Repressor Proteins [D12.776.930.780]

Below are MeSH descriptors whose meaning is related to "Repressor Proteins".

Below are MeSH descriptors whose meaning is more specific than "Repressor Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Repressor Proteins" by people in this website by year, and whether "Repressor Proteins" was a major or minor topic of these publications.

Bar chart showing 189 publications over 29 distinct years, with a maximum of 20 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	3	0	3
1997	0	1	1
1998	0	1	1
1999	2	0	2
2000	0	1	1
2001	1	0	1
2002	6	1	7
2003	2	7	9
2004	5	6	11
2005	17	3	20
2006	4	3	7
2007	6	5	11
2008	3	4	7
2009	5	0	5
2010	4	2	6
2011	2	1	3
2012	7	1	8
2013	6	5	11
2014	5	7	12
2015	6	4	10
2016	6	3	9
2017	6	1	7
2018	2	4	6
2019	4	3	7
2020	5	0	5
2021	9	3	12
2022	1	1	2
2023	0	2	2
2024	0	3	3

Below are the most recent publications written about "Repressor Proteins" by people in Profiles.

Pajarillo E, Kim S, Digman A, Ajayi I, Nyarko-Danquah I, Son DS, Aschner M, Lee E. Dopaminergic REST/NRSF is protective against manganese-induced neurotoxicity in mice. J Biol Chem. 2024 Sep; 300(9):107707.

View in: PubMed
Qin M, Fan W, Li L, Xu T, Zhang H, Chen F, Man J, Kombe AJK, Zhang J, Shi Y, Yao X, Yang Z, Hou Z, Ruan K, Liu D. PRMT1 and TDRD3 promote stress granule assembly by rebuilding the protein-RNA interaction network. Int J Biol Macromol. 2024 Oct; 277(Pt 3):134411.

View in: PubMed
Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K. Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2320070121.

View in: PubMed
Brown LK, Kanagasabai T, Li G, Celada SI, Rumph JT, Adunyah SE, Stewart LV, Chen Z. Co-targeting SKP2 and KDM5B inhibits prostate cancer progression by abrogating AKT signaling with induction of senescence and apoptosis. Prostate. 2024 Jun; 84(9):877-887.

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Sun Y, Bae YE, Zhu J, Zhang Z, Zhong H, Yu J, Wu C, Wu L. A splicing transcriptome-wide association study identifies novel altered splicing for Alzheimer's disease susceptibility. Neurobiol Dis. 2023 08; 184:106209.

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Castro VL, Paz D, Virrueta V, Estevao IL, Grajeda BI, Ellis CC, Quintana AM. Missense and nonsense mutations of the zebrafish hcfc1a gene result in contrasting mTor and radial glial phenotypes. Gene. 2023 May 15; 864:147290.

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Pajarillo E, Demayo M, Digman A, Nyarko-Danquah I, Son DS, Aschner M, Lee E. Deletion of RE1-silencing transcription factor in striatal astrocytes exacerbates manganese-induced neurotoxicity in mice. Glia. 2022 10; 70(10):1886-1901.

View in: PubMed
Heyliger SO, Soliman KFA, Saulsbury MD, Reams RR. Prognostic Relevance of ZNF844 and Chr 19p13.2 KRAB-Zinc Finger Proteins in Clear Cell Renal Carcinoma. Cancer Genomics Proteomics. 2022 May-Jun; 19(3):305-327.

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Pajarillo E, Digman A, Nyarko-Danquah I, Son DS, Soliman KFA, Aschner M, Lee E. Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity. J Biol Chem. 2021 12; 297(6):101372.

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Ortiz-Hernandez GL, Sanchez-Hernandez ES, Ochoa PT, Elix CC, Alkashgari HR, McMullen JRW, Soto U, Martinez SR, Diaz Osterman CJ, Mahler M, Roy S, Casiano CA. The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells. Cells. 2021 10 12; 10(10).

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