Protein Multimerization

"Protein Multimerization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The assembly of the QUATERNARY PROTEIN STRUCTURE of multimeric proteins (MULTIPROTEIN COMPLEXES) from their composite PROTEIN SUBUNITS.

Descriptor ID	D055503
MeSH Number(s)	G02.111.694
Concept/Terms	Protein Multimerization Protein Multimerization Multimerization, Protein Protein Multimer Assembly Assembly, Protein Multimer Multimer Assembly, Protein Protein Heteromultimerizaton Protein Heteromultimerizaton Heteromultimerizaton, Protein Heteromultimerizatons, Protein Protein Trimerization Protein Trimerization Trimerization, Protein Protein Dimerization Protein Dimerization Dimerization, Protein

Below are MeSH descriptors whose meaning is more general than "Protein Multimerization".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Protein Multimerization [G02.111.694]

Below are MeSH descriptors whose meaning is related to "Protein Multimerization".

Below are MeSH descriptors whose meaning is more specific than "Protein Multimerization".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein Multimerization" by people in this website by year, and whether "Protein Multimerization" was a major or minor topic of these publications.

Bar chart showing 95 publications over 19 distinct years, with a maximum of 11 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2002	0	1	1
2008	0	1	1
2009	1	3	4
2010	3	7	10
2011	4	6	10
2012	1	5	6
2013	5	6	11
2014	0	4	4
2015	2	3	5
2016	3	3	6
2017	2	5	7
2018	1	3	4
2019	2	3	5
2020	4	3	7
2021	0	6	6
2023	1	0	1
2024	2	1	3
2025	2	1	3

Below are the most recent publications written about "Protein Multimerization" by people in Profiles.

Maniaci B, Mealka M, Bobkov AA, Stec B, Huxford T, Love JJ. Incorporating Metal-Ligand and Salt-Bridge Interactions in the Design of Protein Heterodimers. Biochemistry. 2025 Aug 05; 64(15):3237-3247.

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Gemeinhardt TM, Regy RM, Phan TM, Pal N, Sharma J, Senkovich O, Mendiola AJ, Ledterman HJ, Henrickson A, Lopes D, Kapoor U, Bihani A, Sihou D, Kim YC, Jeruzalmi D, Demeler B, Kim CA, Mittal J, Francis NJ. A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization. Mol Cell. 2025 Jun 05; 85(11):2128-2146.e15.

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Ahmad A, Tigabu B, Ivanov A, Jerebtsova M, Ammosova T, Ramanathan P, Kumari N, Brantner CA, Pietzsch CA, Simhadri J, Abdullah G, Uversky VN, Paromov V, Popratiloff A, Widen S, Bukreyev A, Nekhai S. Ebola virus nucleoprotein interaction with host protein phosphatase-1 regulates its dimerization and capsid formation. J Biol Chem. 2025 06; 301(6):108541.

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Zhu N, Rogers WE, Heidary DK, Huxford T. Structural and biochemical analyses of the nuclear I?B? protein in complex with the NF-?B p50 homodimer. Genes Dev. 2024 Jul 19; 38(11-12):528-535.

View in: PubMed
Barylko B, Taylor CA, Wang J, Hedde PN, Chen Y, Hur KH, Binns DD, Brautigam CA, DeMartino GN, Mueller JD, Jameson DM, Albanesi JP. Analysis of Arc/Arg3.1 Oligomerization In Vitro and in Living Cells. Int J Mol Sci. 2024 Jun 12; 25(12).

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Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C. Mechanism of ?-Pro/C-degron recognition by the CRL2FEM1B ubiquitin ligase. Nat Commun. 2024 Apr 26; 15(1):3558.

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Calhoun JC, Damania B, Griffith JD, Costantini LM. Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein. J Virol. 2023 10 31; 97(10):e0063723.

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Chuang TD, Quintanilla D, Boos D, Khorram O. Long Noncoding RNA MIAT Modulates the Extracellular Matrix Deposition in Leiomyomas by Sponging MiR-29 Family. Endocrinology. 2021 11 01; 162(11).

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Wang X, Zeng C, Liao S, Zhu Z, Zhang J, Tu X, Yao X, Feng X, Guang S, Xu C. Molecular basis for PICS-mediated piRNA biogenesis and cell division. Nat Commun. 2021 09 22; 12(1):5595.

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Leysen S, Burnley RJ, Rodriguez E, Milroy LG, Soini L, Adamski CJ, Nitschke L, Davis R, Obsil T, Brunsveld L, Crabbe T, Zoghbi HY, Ottmann C, Davis JM. A Structural Study of the Cytoplasmic Chaperone Effect of 14-3-3 Proteins on Ataxin-1. J Mol Biol. 2021 09 17; 433(19):167174.

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