Antihypertensive Agents

"Antihypertensive Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

Descriptor ID	D000959
MeSH Number(s)	D27.505.954.411.162
Concept/Terms	Antihypertensive Agents Antihypertensive Agents Agents, Antihypertensive Antihypertensives Anti-Hypertensives Anti Hypertensives Antihypertensive Drugs Drugs, Antihypertensive Anti-Hypertensive Agents Agents, Anti-Hypertensive Anti Hypertensive Agents Anti-Hypertensive Drugs Anti Hypertensive Drugs Drugs, Anti-Hypertensive

Below are MeSH descriptors whose meaning is more general than "Antihypertensive Agents".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Therapeutic Uses [D27.505.954]
Cardiovascular Agents [D27.505.954.411]
Antihypertensive Agents [D27.505.954.411.162]

Below are MeSH descriptors whose meaning is related to "Antihypertensive Agents".

Below are MeSH descriptors whose meaning is more specific than "Antihypertensive Agents".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antihypertensive Agents" by people in this website by year, and whether "Antihypertensive Agents" was a major or minor topic of these publications.

Bar chart showing 253 publications over 29 distinct years, with a maximum of 19 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	3	0	3
1997	1	0	1
1998	1	1	2
1999	2	0	2
2001	2	0	2
2002	3	1	4
2003	7	8	15
2004	1	4	5
2005	5	1	6
2006	8	1	9
2007	8	5	13
2008	11	6	17
2009	10	9	19
2010	5	5	10
2011	6	2	8
2012	8	3	11
2013	8	2	10
2014	10	2	12
2015	10	1	11
2016	7	5	12
2017	6	5	11
2018	10	3	13
2019	12	3	15
2020	10	6	16
2021	3	6	9
2022	0	3	3
2023	1	7	8
2024	3	1	4
2025	2	0	2

Below are the most recent publications written about "Antihypertensive Agents" by people in Profiles.

Pugsley MK, Bhatt S, Gottfridsson C, Hoffmann P, Koshman YE, Norton K, O'Brien CE, Pierson J, Rossman EI, Taraboletti A, Zabka TS, Foley CM. Advancing nonclinical blood pressure assessment: Current practices and future directions in drug development. Regul Toxicol Pharmacol. 2026 Aug; 169:106098.

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Parrelli GA, Musey PI, Kuhn D. Hypertensive emergency department patients frequently have no existing hypertension diagnosis or antihypertensive medications. J Hypertens. 2026 Jun 01; 44(6):1071-1073.

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Eadon MT, Cavanaugh KL, She L, Steen-Burrell KA, Mohottige D, Nadkarni GN, Kitzman H, Chakraborty H, Empey PE, Limdi NA, Singh R, Beasley CM, Parker AS, Cicali EJ, Ramos MA, Clermont S, Dodgen L, Elwood EN, Robinson M, Umeukeje EM, Garcia Ortega A, Shroff N, Rosenman MB, Nguyen KA, Volpi S, Rider R, Dexter PR, Skaar TC, Peterson JF, Cavallari LH, Johnson JA, Wyatt CM, Orlando LA, Cooper-DeHoff RM, Horowitz CR. Genetic Testing for APOL1 in Adults With Hypertension: The GUARDD-US Randomized Clinical Trial. JAMA Netw Open. 2026 Mar 02; 9(3):e260528.

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Garrison SR, Bakal JA, Kolber MR, Korownyk CS, Green LA, Kirkwood JEM, McAlister FA, Padwal RS, Lewanczuk R, Hill MD, Singer AG, Katz A, Kelmer MD, Gayayan A, Campbell FN, Vucenovic A, Archibald NR, Yeung JMS, Youngson ERE, McGrail K, O'Neill BG, Greiver M, Manca DP, Kraut RY, Wang T, Manns BJ, Mangin DA, MacLean C, McCormack J, Wong ST, Norris C, Allan GM. Antihypertensive Medication Timing and Cardiovascular Events and Death: The BedMed Randomized Clinical Trial. JAMA. 2025 06 17; 333(23):2061-2072.

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Laffin LJ, Kopjar B, Melgaard C, Wolski K, Ibbitson J, Bhikam S, Weir MR, Ofili EO, Mehra R, Luther JM, Cohen DL, Sarraju A, Wilkinson MJ, Flack JM, Rodman D, Nissen SE. Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension. N Engl J Med. 2025 May 08; 392(18):1813-1823.

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Chen MT, Vollmer BL, Blyler CA, Cameron NA, Miller EC, Huang Y, Friedman AM, Wright JD, Boehme AK, Bello NA. Antihypertensive medication prescription dispensation among pregnant women in the United States: A cohort study. Am Heart J. 2024 12; 278:5-13.

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Akinyelure OP, Jaeger BC, Safford MM, Oparil S, Carson AP, Sims A, Hannon L, Howard G, Muntner P, Hardy ST. Social Determinants of Health and Incident Apparent Treatment-Resistant Hypertension Among White and Black US Adults: The REGARDS Study. J Am Heart Assoc. 2024 May 21; 13(10):e031695.

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Maykin MM, Mercer E, Saiki KM, Kaneshiro B, Miller CB, Tsai PS. Furosemide to lower antenatal severe hypertension: a randomized placebo-controlled trial. Am J Obstet Gynecol MFM. 2024 04; 6(4):101348.

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Yaacoub S, Boudaka A, AlKhatib A, Pintus G, Sahebkar A, Kobeissy F, Eid AH. The pharmaco-epigenetics of hypertension: a focus on microRNA. Mol Cell Biochem. 2024 Dec; 479(12):3255-3271.

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Rice B, Mbatidde L, Oluleye O, Onwuanyi A, Adedinsewo D. Managing hypertension in African Americans with heart failure: A guide for the primary care clinician. J Natl Med Assoc. 2024 Oct; 116(5):477-489.

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