Protein Binding

"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.

Descriptor ID	D011485
MeSH Number(s)	G02.111.679 G03.808
Concept/Terms	Protein Binding Protein Binding Binding, Protein Plasma Protein Binding Capacity Plasma Protein Binding Capacity

Below are MeSH descriptors whose meaning is more general than "Protein Binding".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Protein Binding [G02.111.679]
Metabolism [G03]
Protein Binding [G03.808]

Below are MeSH descriptors whose meaning is related to "Protein Binding".

Below are MeSH descriptors whose meaning is more specific than "Protein Binding".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.

Bar chart showing 822 publications over 31 distinct years, with a maximum of 59 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	4	4
1995	0	7	7
1996	0	9	9
1997	0	5	5
1998	0	3	3
1999	1	7	8
2000	0	14	14
2001	0	14	14
2002	0	38	38
2003	0	36	36
2004	0	44	44
2005	2	47	49
2006	0	33	33
2007	0	36	36
2008	0	33	33
2009	1	38	39
2010	0	36	36
2011	0	59	59
2012	0	55	55
2013	0	40	40
2014	0	35	35
2015	0	47	47
2016	0	29	29
2017	1	32	33
2018	0	29	29
2019	0	20	20
2020	0	21	21
2021	0	27	27
2022	0	7	7
2023	0	5	5
2024	3	4	7

Below are the most recent publications written about "Protein Binding" by people in Profiles.

Zhu N, Rogers WE, Heidary DK, Huxford T. Structural and biochemical analyses of the nuclear I?B? protein in complex with the NF-?B p50 homodimer. Genes Dev. 2024 Jul 19; 38(11-12):528-535.

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Mahase V, Sobitan A, Yao Q, Shi X, Qin H, Kidane D, Tang Q, Teng S. Impact of Missense Mutations on Spike Protein Stability and Binding Affinity in the Omicron Variant. Viruses. 2024 Jul 17; 16(7).

View in: PubMed
Holmes J, Islam SM, Milligan KA. Exploring Cannabinoids as Potential Inhibitors of SARS-CoV-2 Papain-like Protease: Insights from Computational Analysis and Molecular Dynamics Simulations. Viruses. 2024 May 30; 16(6).

View in: PubMed
Sarkar M, Ma J, Tapadar S, Caggia S, Oyelere AK, Khan SA, Xie H. Development and validation of a sensitive LC-MS/MS assay of GT-14, a novel Gai2 inhibitor, in rat plasma, and its application in pharmacokinetic study. J Pharm Biomed Anal. 2024 Aug 01; 245:116183.

View in: PubMed
Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C. Mechanism of ?-Pro/C-degron recognition by the CRL2FEM1B ubiquitin ligase. Nat Commun. 2024 Apr 26; 15(1):3558.

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Yadav A, Vukovic L, Narayan M. An Atomic and Molecular Insight into How PFOA Reduces a-Helicity, Compromises Substrate Binding, and Creates Binding Pockets in a Model Globular Protein. J Am Chem Soc. 2024 May 08; 146(18):12766-12777.

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Wu F, Akbar H, Wang C, Yuan X, Dou Z, Mullen M, Niu L, Zhang L, Zang J, Wang Z, Yao X, Song X, Liu X. Sgo1 interacts with CENP-A to guide accurate chromosome segregation in mitosis. J Mol Cell Biol. 2024 Apr 04; 15(10).

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Calhoun JC, Damania B, Griffith JD, Costantini LM. Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein. J Virol. 2023 10 31; 97(10):e0063723.

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Saha B, Bhardwaj U, Goss DJ. Thermodynamically Favorable Interactions between eIF4E Binding Domain of eIF4GI with Structured 5'-Untranslated Regions Drive Cap-Independent Translation of Selected mRNAs. Biochemistry. 2023 06 06; 62(11):1767-1775.

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Cai T, Xie L, Zhang S, Chen M, He D, Badkul A, Liu Y, Namballa HK, Dorogan M, Harding WW, Mura C, Bourne PE, Xie L. End-to-end sequence-structure-function meta-learning predicts genome-wide chemical-protein interactions for dark proteins. PLoS Comput Biol. 2023 01; 19(1):e1010851.

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