Protein Binding

"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.

Descriptor ID	D011485
MeSH Number(s)	G02.111.679 G03.808
Concept/Terms	Protein Binding Protein Binding Binding, Protein Plasma Protein Binding Capacity Plasma Protein Binding Capacity

Below are MeSH descriptors whose meaning is more general than "Protein Binding".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Protein Binding [G02.111.679]
Metabolism [G03]
Protein Binding [G03.808]

Below are MeSH descriptors whose meaning is related to "Protein Binding".

Below are MeSH descriptors whose meaning is more specific than "Protein Binding".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.

Bar chart showing 779 publications over 30 distinct years, with a maximum of 58 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	4	4
1995	0	7	7
1996	0	8	8
1997	0	5	5
1998	0	4	4
1999	1	7	8
2000	0	15	15
2001	0	12	12
2002	0	28	28
2003	0	35	35
2004	0	43	43
2005	2	44	46
2006	0	28	28
2007	0	36	36
2008	0	33	33
2009	1	37	38
2010	0	36	36
2011	0	58	58
2012	0	53	53
2013	0	39	39
2014	0	35	35
2015	0	44	44
2016	0	28	28
2017	1	31	32
2018	0	27	27
2019	0	20	20
2020	0	21	21
2021	0	24	24
2022	0	7	7
2023	0	5	5

Below are the most recent publications written about "Protein Binding" by people in Profiles.

Calhoun JC, Damania B, Griffith JD, Costantini LM. Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein. J Virol. 2023 10 31; 97(10):e0063723.

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Saha B, Bhardwaj U, Goss DJ. Thermodynamically Favorable Interactions between eIF4E Binding Domain of eIF4GI with Structured 5'-Untranslated Regions Drive Cap-Independent Translation of Selected mRNAs. Biochemistry. 2023 06 06; 62(11):1767-1775.

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Cai T, Xie L, Zhang S, Chen M, He D, Badkul A, Liu Y, Namballa HK, Dorogan M, Harding WW, Mura C, Bourne PE, Xie L. End-to-end sequence-structure-function meta-learning predicts genome-wide chemical-protein interactions for dark proteins. PLoS Comput Biol. 2023 01; 19(1):e1010851.

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Huang W, Zhang QC. Prediction of Dynamic RBP-RNA Interactions Using PrismNet. Methods Mol Biol. 2023; 2568:123-132.

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Ortiz NR, Guy N, Garcia YA, Sivils JC, Galigniana MD, Cox MB. Functions of the Hsp90-Binding FKBP Immunophilins. Subcell Biochem. 2023; 101:41-80.

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Song X, Yang F, Yang T, Wang Y, Ding M, Li L, Xu P, Liu S, Dai M, Chi C, Xiang S, Xu C, Li D, Wang Z, Li L, Hill DL, Fu C, Yuan K, Li P, Zang J, Hou Z, Jiang K, Shi Y, Liu X, Yao X. Phase separation of EB1 guides microtubule plus-end dynamics. Nat Cell Biol. 2023 Jan; 25(1):79-91.

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Ovchynnykova O, Kapusta K, Sizochenko N, Sukhyy KM, Kolodziejczyk W, Hill GA, Saloni J. Homology Modeling and Molecular Dynamics-Driven Search for Natural Inhibitors That Universally Target Receptor-Binding Domain of Spike Glycoprotein in SARS-CoV-2 Variants. Molecules. 2022 Oct 28; 27(21).

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Guo Q, Zhao S, Francisco-Velilla R, Zhang J, Embarc-Buh A, Abellan S, Lv M, Tang P, Gong Q, Shen H, Sun L, Yao X, Min J, Shi Y, Mart?nez-Salas E, Zhang K, Xu C. Structural basis for Gemin5 decamer-mediated mRNA binding. Nat Commun. 2022 09 02; 13(1):5166.

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Dankwah KO, Mohl JE, Begum K, Leung MY. What Makes GPCRs from Different Families Bind to the Same Ligand? Biomolecules. 2022 06 21; 12(7).

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Kehinde IA, Egbejimi A, Kaur M, Onyenaka C, Adebusuyi T, Olaleye OA. Inhibitory mechanism of Ambroxol and Bromhexine Hydrochlorides as potent blockers of molecular interaction between SARS-CoV-2 spike protein and human angiotensin-converting Enzyme-2. J Mol Graph Model. 2022 07; 114:108201.

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