Below are the most recent publications written about "Down-Regulation" by people in Profiles.
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Deng Z, Pu L, Deng K, Liu W, Zhang J, Zhang L, Meng Q, Zhou W, Jin H, Xu D, Qi S, Wu Z, Ma Y, Liu X, Yao X, Ke B, Kerr DJ, Yang L, Yang J, Jiang H. Targeting TFAP2? condensation suppresses the development of esophageal squamous cell carcinoma. Cell. 2026 Feb 05; 189(3):887-905.e25.
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Chen Q, Dorji JP, Perera SG, Li P, Aijaz F, Ihuoma LC, Matsui H, Awah CU. In vivo inhibition of c-MYC in the metastatic drug-resistant ovarian cancer cells down regulates the c-MYC-PD-L1-PAX8-p21 to achieve therapeutic efficacy. BMC Cancer. 2025 Dec 10; 26(1):68.
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Altinok FA, Dallali I, Hasan A, Boubekka A, Tilki EK, Ozturk Y. Alcohol-induced neuropathy associated downregulation of Kv7 channels in primary nociceptors. Neurosci Lett. 2026 Jan 10; 871:138461.
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Armina-Rodriguez A, Vald?s Fernandez BN, Ocasio-Malav? C, Cantres Rosario YM, Carrasquillo Carri?n K, Mel?ndez LM, Roche Lima A, Tosado Rodriguez EL, Espino AM. Quantitative Proteomics Reveals Fh15 as an Antagonist of TLR4 Downregulating the Activation of NF-?B, Inducible Nitric Oxide, Phagosome Signaling Pathways, and Oxidative Stress of LPS-Stimulated Macrophages. Int J Mol Sci. 2025 Jul 18; 26(14).
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Sugawara S, Hueber B, Woolley G, Terry K, Kroll K, Manickam C, Ram DR, Ndhlovu LC, Goepfert P, Jost S, Reeves RK. Multiplex interrogation of the NK cell signalome reveals global downregulation of CD16 signaling during lentivirus infection through an IL-18/ADAM17-dependent mechanism. PLoS Pathog. 2023 09; 19(9):e1011629.
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Simino LAP, Baqueiro MN, Panzarin C, Lopes PKF, G?is MM, Simabuco FM, Ign?cio-Souza LM, Milanski M, Ross MG, Desai M, Torsoni AS, Torsoni MA. Hypothalamic a7 nicotinic acetylcholine receptor (a7nAChR) is downregulated by TNFa-induced Let-7 overexpression driven by fatty acids. FASEB J. 2023 09; 37(9):e23120.
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Adinew GM, Messeha SS, Taka E, Badisa RB, Soliman KFA. Anticancer Effects of Thymoquinone through the Antioxidant Activity, Upregulation of Nrf2, and Downregulation of PD-L1 in Triple-Negative Breast Cancer Cells. Nutrients. 2022 Nov 13; 14(22).
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Liu X, Chipurupalli S, Jiang P, Tavasoli M, Yoo BH, McPhee M, Mazinani S, Francia G, Kerbel RS, Rosen KV. ErbB2/Her2-dependent downregulation of a cell death-promoting protein BLNK in breast cancer cells is required for 3D breast tumor growth. Cell Death Dis. 2022 08 06; 13(8):687.
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Ajibade T, Akinrinde A, Adetona M, Oyagbemi A, Adedapo A, Larbie C, Omobowale T, Ola-Davies O, Saba A, Adedapo A, Oguntibeju O, Yakubu M. Luteolin normalizes blood pressure via its antioxidant activity and down-regulation of renal Angiotensin II receptor and Mineralocorticoid receptor expressions in rats co-exposed to Diclofenac and sodium fluoride. Niger J Physiol Sci. 2022 Jun 30; 37(1):35-42.
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Gant DMA, Parris AB, Yang X. Metformin-induced downregulation of c-Met is a determinant of sensitivity in MDA-MB-468 breast cancer cells. Biochem Biophys Res Commun. 2022 07 12; 613:100-106.