"MicroRNAs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
| Descriptor ID |
D035683
|
| MeSH Number(s) |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
|
| Concept/Terms |
MicroRNAs- MicroRNAs
- MicroRNA
- miRNAs
- Micro RNA
- RNA, Micro
- miRNA
Primary MicroRNA- Primary MicroRNA
- MicroRNA, Primary
- Primary miRNA
- miRNA, Primary
- pri-miRNA
- pri miRNA
|
Below are MeSH descriptors whose meaning is more general than "MicroRNAs".
Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".
This graph shows the total number of publications written about "MicroRNAs" by people in this website by year, and whether "MicroRNAs" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 |
| 2004 | 2 | 0 | 2 |
| 2005 | 2 | 0 | 2 |
| 2007 | 2 | 2 | 4 |
| 2008 | 3 | 1 | 4 |
| 2009 | 7 | 1 | 8 |
| 2010 | 8 | 2 | 10 |
| 2011 | 10 | 4 | 14 |
| 2012 | 16 | 1 | 17 |
| 2013 | 22 | 6 | 28 |
| 2014 | 18 | 8 | 26 |
| 2015 | 22 | 6 | 28 |
| 2016 | 23 | 5 | 28 |
| 2017 | 20 | 4 | 24 |
| 2018 | 21 | 3 | 24 |
| 2019 | 16 | 4 | 20 |
| 2020 | 26 | 5 | 31 |
| 2021 | 25 | 2 | 27 |
| 2022 | 25 | 1 | 26 |
| 2023 | 13 | 0 | 13 |
| 2024 | 19 | 3 | 22 |
| 2025 | 4 | 1 | 5 |
To return to the timeline,
click here.
Below are the most recent publications written about "MicroRNAs" by people in Profiles.
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Chuang TD, Wiseman A, Alfaro G, Rysling S, Ton N, Baghdasarian D, Khorram O. Transcriptomic and functional analysis of fibroid extracellular vesicles. Clin Sci (Lond). 2026 May 20; 140(5):805-824.
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Chuang TD, Yu C, Liu J, Khorram O, Umar S, Rehan VK. Perinatal Nicotine Exposure-Induced Cardiac Phenotype Is Mediated by miR-1-MIAT Interaction and Is Transmitted Transgenerationally. FASEB J. 2026 Mar 31; 40(6):e71711.
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Huang MB, Yan F, Jadoon U, Wu JY, Brena D, Johnson EL, Stiles J, Yang L, Rivers BM, Bond VC. SMR Peptide Modulates Tumor-Derived Extracellular Vesicles microRNA and Inflammatory Transcript Signatures in TNBC. Cells. 2026 Mar 19; 15(6).
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Mondal T, Korba BE, Loffredo CA, Smith CI, Quartey R, Sahota J, Moses G, Howell CD, Nunlee-Bland G, Sherif ZA, Ghosh S. Transcriptomic Profiling of MicroRNA and Non-Coding RNA from Whole Blood of African Americans with MASLD. Int J Mol Sci. 2026 Feb 09; 27(4).
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Dye CK, Kupsco A, Jackson GL, Glabonjat RA, Hakim A, Castro-Martinez A, Laurent LC, Umans JG, Goessler W, Cole SA, Baccarelli AA, Navas-Acien A, Wu H. Extracellular vesicle microRNAs as an epigenetic biosignature of arsenic-associated diabetes in the Strong Heart Study. Environ Res. 2026 Feb 15; 291:123573.
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Pochana G, Karanam TS, Mack S, Karanam B. Garcinol as an Epigenetic Modulator: Mechanisms of Anti-Cancer Activity and Therapeutic Potential. Int J Mol Sci. 2025 Nov 11; 26(22).
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Toldo N, Wu Y, Fabbri M. Extracellular Vesicle microRNAs in the Crosstalk Between Cancer Cells and Natural Killer (NK) Cells. Cells. 2025 Oct 29; 14(21).
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Pacurari M, Cox I, Farah I. MiR-1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion. Environ Toxicol. 2025 Nov; 40(11):1249-1260.
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Zhou N, Yuan Y, Lin H, Wang J, Lin H, Ashktorab H, Smoot D, Jin Z, Zhuang S, Qin Y. Epigallocatechin Gallate Induces miR-192/215 Suppression of EGR1 in Gastric Cancer. Anticancer Res. 2025 May; 45(5):1935-1951.
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Nathani A, Sun L, Li Y, Lazarte J, Aare M, Singh M. Targeting EGFR-TKI resistance in lung cancer: Role of miR-5193/miR-149-5p loaded NK-EVs and Carboplatin combination. Int J Pharm. 2025 Apr 30; 675:125573.