"RNA, Small Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Short chains of RNA (100-300 nucleotides long) that are abundant in the nucleus and usually complexed with proteins in snRNPs (RIBONUCLEOPROTEINS, SMALL NUCLEAR). Many function in the processing of messenger RNA precursors. Others, the snoRNAs (RNA, SMALL NUCLEOLAR), are involved with the processing of ribosomal RNA precursors.
Descriptor ID |
D012342
|
MeSH Number(s) |
D13.444.735.628.818 D13.444.735.790.552.937
|
Concept/Terms |
RNA, Small Nuclear- RNA, Small Nuclear
- snRNA
- Small Nuclear RNA
- Low Molecular Weight Nuclear RNA
- Small Molecular Weight RNA
|
Below are MeSH descriptors whose meaning is more general than "RNA, Small Nuclear".
Below are MeSH descriptors whose meaning is more specific than "RNA, Small Nuclear".
This graph shows the total number of publications written about "RNA, Small Nuclear" by people in this website by year, and whether "RNA, Small Nuclear" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2014 | 1 | 1 | 2 |
2020 | 1 | 1 | 2 |
2022 | 1 | 0 | 1 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA, Small Nuclear" by people in Profiles.
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Zhang X, Zhan X, Bian T, Yang F, Li P, Lu Y, Xing Z, Fan R, Zhang QC, Shi Y. Structural insights into branch site proofreading by human spliceosome. Nat Struct Mol Biol. 2024 May; 31(5):835-845.
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Guo Q, Zhao S, Francisco-Velilla R, Zhang J, Embarc-Buh A, Abellan S, Lv M, Tang P, Gong Q, Shen H, Sun L, Yao X, Min J, Shi Y, Mart?nez-Salas E, Zhang K, Xu C. Structural basis for Gemin5 decamer-mediated mRNA binding. Nat Commun. 2022 09 02; 13(1):5166.
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Chu H, Perea W, Greenbaum NL. Role of the central junction in folding topology of the protein-free human U2-U6 snRNA complex. RNA. 2020 07; 26(7):836-850.
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Yin Y, Lu JY, Zhang X, Shao W, Xu Y, Li P, Hong Y, Cui L, Shan G, Tian B, Zhang QC, Shen X. U1 snRNP regulates chromatin retention of noncoding RNAs. Nature. 2020 04; 580(7801):147-150.
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Shi L, Zhang Z, Yu AM, Wang W, Wei Z, Akhter E, Maurer K, Costa Reis P, Song L, Petri M, Sullivan KE. The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs. PLoS One. 2014; 9(5):e93846.
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Zhao C, Anklin C, Greenbaum NL. Use of ??F NMR methods to probe conformational heterogeneity and dynamics of exchange in functional RNA molecules. Methods Enzymol. 2014; 549:267-85.
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Zhao C, Bachu R, Popovic M, Devany M, Brenowitz M, Schlatterer JC, Greenbaum NL. Conformational heterogeneity of the protein-free human spliceosomal U2-U6 snRNA complex. RNA. 2013 Apr; 19(4):561-73.
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Popovic M, Nelson JD, Schroeder KT, Greenbaum NL. Impact of base pair identity 5' to the spliceosomal branch site adenosine on branch site conformation. RNA. 2012 Nov; 18(11):2093-103.
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Yuan F, Griffin L, Phelps L, Buschmann V, Weston K, Greenbaum NL. Use of a novel F?rster resonance energy transfer method to identify locations of site-bound metal ions in the U2-U6 snRNA complex. Nucleic Acids Res. 2007; 35(9):2833-45.
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Xu D, Greenbaum NL, Fenley MO. Recognition of the spliceosomal branch site RNA helix on the basis of surface and electrostatic features. Nucleic Acids Res. 2005; 33(4):1154-61.