Epigenesis, Genetic

"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.

Descriptor ID	D044127
MeSH Number(s)	G05.308.203
Concept/Terms	Epigenesis, Genetic Epigenesis, Genetic Genetic Epigenesis Epigenetic Processes Epigenetic Processes Processes, Epigenetic Epigenetics Processes Processes, Epigenetics Epigenetic Process Process, Epigenetic

Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".

Biological Sciences [G]
Genetic Phenomena [G05]
Gene Expression Regulation [G05.308]
Epigenesis, Genetic [G05.308.203]

Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.

Bar chart showing 221 publications over 22 distinct years, with a maximum of 20 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	1	2
2005	1	0	1
2006	0	1	1
2007	1	2	3
2008	2	0	2
2009	4	5	9
2010	3	3	6
2011	2	5	7
2012	5	4	9
2013	8	7	15
2014	5	9	14
2015	9	4	13
2016	9	9	18
2017	3	4	7
2018	8	8	16
2019	5	6	11
2020	5	11	16
2021	9	7	16
2022	2	8	10
2023	1	8	9
2024	7	13	20
2025	10	6	16

Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.

Miller MW, Zhao X, Wolf EJ, Milberg WP, Fortier CB, Logue MW. Genetic and epigenetic analysis of plasma glial fibrillary acidic protein (GFAP) levels in PTSD. Mol Psychiatry. 2026 Jan; 31(1):352-361.

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Rubas NC, Torres A, Maunakea AK. The Gut Microbiome and Epigenomic Reprogramming: Mechanisms, Interactions, and Implications for Human Health and Disease. Int J Mol Sci. 2025 Sep 05; 26(17).

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Patel P, Shen A, Perez C, Kennedy EM, Shankar K, Pearson KJ, Andres A, Everson TM. Association between placental epigenetic age acceleration and early postnatal growth patterns. Sci Rep. 2025 Aug 12; 15(1):29597.

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Wu X, Hernandez FV, Wang H, Wang R, Shiffka S, Shah N, Carr SR, Hoang CD, Blakely AM, Lebensohn A, Mishra K, Xi S, Zhang MR, Tolunay T, Gara S, Absher A, Francis D, Rowland A, Connolly M, Jacobs S, Orfgen S, Driscoll K, Ghafoor A, Lu X, Malouf GG, Yang H, Carbone M, Hassan R, Jones E, Miettinen M, Schrump DS. Prospective Analysis of Mesotheliomas in Subjects With BAP1 Cancer Syndrome: Clinical Characteristics and Epigenetic Correlates of Disease. J Thorac Oncol. 2025 Nov; 20(11):1699-1715.

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Allan NP, Torres A, Corley MJ, Yamamoto BY, Balaan C, Yamauchi Y, Peres R, Qin Y, Khadka VS, Deng Y, Ward MA, Maunakea AK. Pre-Conception Maternal Obesity Confers Autism Spectrum Disorder-like Behaviors in Mice Offspring Through Neuroepigenetic Dysregulation. Cells. 2025 Aug 05; 14(15).

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Abrishamcar S, Aqua JK, Dye C, Jones-Antwi R, Chen Y, Gallo LC, Llabre MM, Perreira KM, Daviglus ML, Argos M, Thyagarajan B, H?ls A, Baccarelli A, Cai J, Isasi CR, Kaplan RC, Conneely KN, Suglia SF. Cumulative psychosocial factors and epigenetic age acceleration in the Hispanic Community Health Study/Study of Latinos. Epigenomics. 2025 Sep; 17(13):865-877.

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London SE, Hauber ME, McKim-Louder MI, Balakrishnan CN. Simultaneous RNA Sequencing and DNA Methylation Profiling Reveals Neural Mechanisms That Regulate Sensitive Period Behavioral Learning. Genes Brain Behav. 2025 Aug; 24(4):e70031.

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Kocher K, Ngwa J, Bhattacharya S, Donofrio M, Limperopoulos C, Andescavage N. Epigenomic signatures of accelerated epigenetic?aging are associated with congenital heart disease in newborns. BMC Med Genomics. 2025 Jul 28; 18(1):121.

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Chakrabarti S, Wagh C, Bagnall-Moreau C, Uddin F, Reiser J, Salas-Ramirez K, Ahles T, Hubbard K. Chemotherapy treatment alters DNA methylation patterns in the prefrontal cortex of female rat brain. Sci Rep. 2025 Jul 01; 15(1):20681.

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Zhao X, Katrinli S, McCormick BM, Miller MW, Nugent NR, Wani AH, Zannas AS, Aiello AE, Baker DG, Boks MP, Chen CY, Fortier CB, Gelernter J, Geuze E, Koenen KC, Linnstaedt SD, Luykx JJ, Maihofer AX, McLean SA, Milberg WP, Ratanatharathorn A, Ressler KJ, Risbrough VB, Rutten BPF, Smoller JW, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Zhao Y, Logue MW, Nievergelt CM, Smith AK, Uddin M, Wolf EJ. PTSD and epigenetic aging: a longitudinal meta-analysis. Psychol Med. 2025 May 14; 55:e142.

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