DNA Methylation

"DNA Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.

Descriptor ID	D019175
MeSH Number(s)	G02.111.035.538.161 G02.111.218 G03.059.538.161 G05.206
Concept/Terms	DNA Methylation DNA Methylation DNA Methylations Methylation, DNA Methylations, DNA

Below are MeSH descriptors whose meaning is more general than "DNA Methylation".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Alkylation [G02.111.035]
Methylation [G02.111.035.538]
DNA Methylation [G02.111.035.538.161]
DNA Methylation [G02.111.218]
Metabolism [G03]
Alkylation [G03.059]
Methylation [G03.059.538]
DNA Methylation [G03.059.538.161]
Genetic Phenomena [G05]
DNA Methylation [G05.206]

Below are MeSH descriptors whose meaning is related to "DNA Methylation".

Below are MeSH descriptors whose meaning is more specific than "DNA Methylation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA Methylation" by people in this website by year, and whether "DNA Methylation" was a major or minor topic of these publications.

Bar chart showing 313 publications over 29 distinct years, with a maximum of 26 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	2	2
1999	0	1	1
2000	1	0	1
2001	1	0	1
2002	0	1	1
2003	4	5	9
2004	5	2	7
2005	4	5	9
2006	2	2	4
2007	6	5	11
2008	4	2	6
2009	4	3	7
2010	4	4	8
2011	6	2	8
2012	4	7	11
2013	10	14	24
2014	9	4	13
2015	11	7	18
2016	11	5	16
2017	7	8	15
2018	11	6	17
2019	12	4	16
2020	15	10	25
2021	8	4	12
2022	6	5	11
2023	2	9	11
2024	15	11	26
2025	8	11	19
2026	1	3	4

Below are the most recent publications written about "DNA Methylation" by people in Profiles.

Adeyika TA, Datturgi A, Ettinoffe Y, Ghosh S, Albanese C, Kwabi-Addo B. Epigenetic dysregulation and biological function of PDX1 in prostate cancer. Oncotarget. 2026 Mar 31; 17(1):157-172.

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Mishra P, Ma J, Xie H, Li F, Tsai RYL, Liang D. Simultaneous quantification of cytidine, methylcytidine, and hydroxymethylcytidine by isotope-dilution LC-MS/MS with application to mouse liver samples. J Chromatogr A. 2026 Feb 22; 1769:466721.

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Wolf EJ, Zhao X, Madison A, Carbaugh J, Fortier CB, Milberg WP, Logue MW, Miller MW. Trauma exposure, PTSD, and methylation of the blood brain barrier claudin-5 gene. Psychoneuroendocrinology. 2026 Apr; 186:107753.

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Heredia-Negr?n F, Nagamatsu ST, Carrasquillo-Carrion K, Hurd Y, Rompala G, Mel?n K, Garcia-Vassallo G, Roche-Lima A, Montalvo-Ortiz JL. Building epigenetic risk scores of opioid use disorder: Insights from human postmortem brain data. Transl Psychiatry. 2026 Jan 09; 16(1):62.

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Chen Y, Abrishamcar S, Aqua JK, Dye C, Gallo LC, Llabre MM, Penedo FJ, Isasi CR, Perreira KM, Thyagarajan B, Daviglus M, Pirzada A, Baccarelli A, Conneely KN, Jones-Antwi R, Suglia SF. Social factors as buffers for the adverse impact of adverse childhood experiences on biological age acceleration among adults in Hispanic Community Health Study / Study of Latinos. Brain Behav Immun. 2026 Feb; 132:106241.

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Sum KK, Burton MA, Alcazar CG, Teh AL, Godfrey KM, Huang JY. Strength of evidence for paternal influence on offspring epigenome in observational human studies: a systematic review and risk-of-bias appraisal for non-randomized exposures. Epigenetics. 2025 Dec; 20(1):2594322.

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Song MA, Gupta A, Park SY, Kim J, Archer KJ, Tiirikainen M, Franke A, Wilkens LR, Le Marchand L, Chung D, Lim U. Differential blood DNA methylation loci between Native Hawaiian and White women are associated with dietary patterns and metabolic biomarkers. Sci Rep. 2025 Nov 28; 15(1):43191.

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Rubas NC, Torres A, Maunakea AK. The Gut Microbiome and Epigenomic Reprogramming: Mechanisms, Interactions, and Implications for Human Health and Disease. Int J Mol Sci. 2025 Sep 05; 26(17).

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Patel P, Shen A, Perez C, Kennedy EM, Shankar K, Pearson KJ, Andres A, Everson TM. Association between placental epigenetic age acceleration and early postnatal growth patterns. Sci Rep. 2025 Aug 12; 15(1):29597.

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Allan NP, Torres A, Corley MJ, Yamamoto BY, Balaan C, Yamauchi Y, Peres R, Qin Y, Khadka VS, Deng Y, Ward MA, Maunakea AK. Pre-Conception Maternal Obesity Confers Autism Spectrum Disorder-like Behaviors in Mice Offspring Through Neuroepigenetic Dysregulation. Cells. 2025 Aug 05; 14(15).

View in: PubMed

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