Methylation

"Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)

Descriptor ID	D008745
MeSH Number(s)	G02.111.035.538 G02.607.094.538 G03.059.538
Concept/Terms	Methylation Methylation Methylations

Below are MeSH descriptors whose meaning is more general than "Methylation".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Alkylation [G02.111.035]
Methylation [G02.111.035.538]
Organic Chemistry Phenomena [G02.607]
Alkylation [G02.607.094]
Methylation [G02.607.094.538]
Metabolism [G03]
Alkylation [G03.059]
Methylation [G03.059.538]

Below are MeSH descriptors whose meaning is related to "Methylation".

Below are MeSH descriptors whose meaning is more specific than "Methylation".

Methylation
DNA Methylation

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Methylation" by people in this website by year, and whether "Methylation" was a major or minor topic of these publications.

Bar chart showing 90 publications over 26 distinct years, with a maximum of 9 publications in 2014

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1994	4	4
1995	1	1
2000	1	1
2001	1	1
2003	2	2
2004	1	1
2005	2	2
2006	4	4
2007	2	2
2008	2	2
2009	4	4
2010	5	5
2011	5	5
2012	8	8
2013	3	3
2014	9	9
2015	6	6
2016	6	6
2017	6	6
2018	6	6
2019	2	2
2020	1	1
2021	3	3
2022	3	3
2023	2	2
2024	1	1

Below are the most recent publications written about "Methylation" by people in Profiles.

Nes WD, Chaudhuri M, Leaver DJ. Druggable Sterol Metabolizing Enzymes in Infectious Diseases: Cell Targets to Therapeutic Leads. Biomolecules. 2024 Feb 20; 14(3).

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Chen J, Rosen BP. Arsenite Methyltransferase Diversity and Optimization of Methylation Efficiency. Environ Sci Technol. 2023 07 04; 57(26):9754-9761.

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Vaid R, Mendez A, Thombare K, Burgos-Panadero R, Robinot R, Fonseca BF, Gandasi NR, Ringlander J, Hassan Baig M, Dong JJ, Cho JY, Reinius B, Chakrabarti LA, Nystrom K, Mondal T. Global loss of cellular m6A RNA methylation following infection with different SARS-CoV-2 variants. Genome Res. 2023 03; 33(3):299-313.

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Chen J, Galv?n AE, Viswanathan T, Yoshinaga M, Rosen BP. Selective Methylation by an ArsM S-Adenosylmethionine Methyltransferase from Burkholderia gladioli GSRB05 Enhances Antibiotic Production. Environ Sci Technol. 2022 10 04; 56(19):13858-13866.

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Sapp N, Burge N, Cox K, Prakash P, Balasubramaniam M, Thapa S, Christensen D, Li M, Linderberger J, Kvaratskhelia M, Pandhare J, Craigie R, Poirier MG, Dash C. HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA. J Virol. 2022 09 28; 96(18):e0101122.

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Shen B, Hernandez DG, Chitrala KN, Fanelli-Kuczmarski MT, Noren Hooten N, Pacheco NL, Mode NA, Zonderman AB, Ezike N, Evans MK. APOE gene region methylation is associated with cognitive performance in middle-aged urban adults. Neurobiol Aging. 2022 08; 116:41-48.

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Bisserier M, Mathiyalagan P, Zhang S, Elmastour F, Dorfm?ller P, Humbert M, David G, Tarzami S, Weber T, Perros F, Sassi Y, Sahoo S, Hadri L. Regulation of the Methylation and Expression Levels of the BMPR2 Gene by SIN3a as a Novel Therapeutic Mechanism in Pulmonary Arterial Hypertension. Circulation. 2021 07 06; 144(1):52-73.

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Yoshinaga-Sakurai K, Rossman TG, Rosen BP. Regulation of arsenic methylation: identification of the transcriptional region of the human AS3MT gene. Cell Biol Toxicol. 2022 10; 38(5):765-780.

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Cook N, Chen J, Zhou J, Wu D. Embryonic Ectoderm Development (EED) as a Novel Target for Cancer Treatment. Curr Top Med Chem. 2021; 21(31):2771-2777.

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Yu R, Wu H, Ismail H, Du S, Cao J, Wang J, Ward T, Yang F, Gui P, Ali M, Chu L, Mo F, Wang Q, Chu Y, Zang J, Zhao Y, Ye M, Fang G, Chen PR, Dou Z, Gao X, Wang W, Liu X, Yao X. Methylation of PLK1 by SET7/9 ensures accurate kinetochore-microtubule dynamics. J Mol Cell Biol. 2020 07 03; 12(6):462-476.

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