A CALCIUM and CALMODULIN-dependent serine/threonine protein phosphatase that is composed of the calcineurin A catalytic subunit and the calcineurin B regulatory subunit. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including HISTONES; MYOSIN LIGHT CHAIN; and the regulatory subunits of CAMP-DEPENDENT PROTEIN KINASES. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes.

Descriptor ID	D019703
MeSH Number(s)	D08.811.277.352.650.625.150 D12.644.360.087 D12.776.476.087
Concept/Terms	Calcineurin Calcineurin Protein Phosphatase 3 Phosphatase 3, Protein Protein Phosphatase-2B Protein Phosphatase 2B Calcineurin B Calcineurin B Protein Phosphatase 3 Regulatory Subunit Calcineurin A Calcineurin A Protein Phosphatase 3 Catalytic Subunit

Below are MeSH descriptors whose meaning is more general than "Calcineurin".

Below are MeSH descriptors whose meaning is related to "Calcineurin".

Below are MeSH descriptors whose meaning is more specific than "Calcineurin".