"B-Cell Activating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN.
Descriptor ID |
D053264
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MeSH Number(s) |
D12.644.276.374.750.061 D12.776.395.191 D12.776.467.374.750.061 D12.776.543.550.193 D23.529.374.750.061
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Concept/Terms |
B-Cell Activating Factor- B-Cell Activating Factor
- Activating Factor, B-Cell
- B-Lymphocyte Activating Factor
- Activating Factor, B-Lymphocyte
- B Lymphocyte Activating Factor
- THANK Protein
- BAFF Ligand
- BLyS Protein
- B Cell Activating Factor
- B Lymphocyte Stimulator
- CD257 Antigen
- Antigen, CD257
- Antigens, CD257
- TNF and APOL-Related Leukocyte Expressed Ligand 1
- TNF and APOL Related Leukocyte Expressed Ligand 1
- TNF Superfamily, Member 13b
- Tumor Necrosis Factor Ligand Superfamily Member 13b
- CD257 Antigens
- TNFSF13B Protein
- TALL-1 Protein
- TALL 1 Protein
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Below are MeSH descriptors whose meaning is more general than "B-Cell Activating Factor".
Below are MeSH descriptors whose meaning is more specific than "B-Cell Activating Factor".
This graph shows the total number of publications written about "B-Cell Activating Factor" by people in this website by year, and whether "B-Cell Activating Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "B-Cell Activating Factor" by people in Profiles.
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Crupi R, Cambiaghi M, Spatz L, Hen R, Thorn M, Friedman E, Vita G, Battaglia F. Reduced adult neurogenesis and altered emotional behaviors in autoimmune-prone B-cell activating factor transgenic mice. Biol Psychiatry. 2010 Mar 15; 67(6):558-66.
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Thorn M, Lewis RH, Mumbey-Wafula A, Kantrowitz S, Spatz LA. BAFF overexpression promotes anti-dsDNA B-cell maturation and antibody secretion. Cell Immunol. 2010; 261(1):9-22.