"Lymphotoxin-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR.
| Descriptor ID |
D008233
|
| MeSH Number(s) |
D12.644.276.374.480.438 D12.644.276.374.750.500 D12.776.467.374.480.438 D12.776.467.374.750.500 D23.529.374.480.438 D23.529.374.750.500
|
| Concept/Terms |
Lymphotoxin-alpha- Lymphotoxin-alpha
- Lymphotoxin alpha
- Lymphotoxin
- Tumor Necrosis Factor-beta
- Tumor Necrosis Factor beta
- TNF-beta
- Tumor Necrosis Factor Ligand Superfamily Member 1
- alpha-Lymphotoxin
- alpha Lymphotoxin
- TNF Superfamily, Member 1
Lymphotoxin-alpha3- Lymphotoxin-alpha3
- Lymphotoxin alpha3
- Soluble Lymphotoxin-alpha
- Lymphotoxin-alpha, Soluble
- Soluble Lymphotoxin alpha
|
Below are MeSH descriptors whose meaning is more general than "Lymphotoxin-alpha".
Below are MeSH descriptors whose meaning is more specific than "Lymphotoxin-alpha".
This graph shows the total number of publications written about "Lymphotoxin-alpha" by people in this website by year, and whether "Lymphotoxin-alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lymphotoxin-alpha" by people in Profiles.
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Campbell MC, Ashong B, Teng S, Harvey J, Cross CN. Multiple selective sweeps of ancient polymorphisms in and around LTa located in the MHC class III region on chromosome 6. BMC Evol Biol. 2019 12 02; 19(1):218.
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Hoffmann P, Sturm A, Stein J, Dignass AU. Interferon-? modulates intestinal epithelial cell function in-vitro through a TGF?-dependent mechanism. Regul Pept. 2011 Jun 07; 168(1-3):27-31.
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Oldstone MB, Race R, Thomas D, Lewicki H, Homann D, Smelt S, Holz A, Koni P, Lo D, Chesebro B, Flavell R. Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion. J Virol. 2002 May; 76(9):4357-63.