"Asialoglycoproteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endogenous glycoproteins from which SIALIC ACID has been removed by the action of sialidases. They bind tightly to the ASIALOGLYCOPROTEIN RECEPTOR which is located on hepatocyte plasma membranes. After internalization by adsorptive ENDOCYTOSIS they are delivered to LYSOSOMES for degradation. Therefore receptor-mediated clearance of asialoglycoproteins is an important aspect of the turnover of plasma glycoproteins. They are elevated in serum of patients with HEPATIC CIRRHOSIS or HEPATITIS.
| Descriptor ID |
D001212
|
| MeSH Number(s) |
D12.776.395.140
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Asialoglycoproteins".
Below are MeSH descriptors whose meaning is more specific than "Asialoglycoproteins".
This graph shows the total number of publications written about "Asialoglycoproteins" by people in this website by year, and whether "Asialoglycoproteins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Asialoglycoproteins" by people in Profiles.
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Kittur FS, Arthur E, Nguyen M, Hung CY, Sane DC, Xie J. Two-step purification procedure for recombinant human asialoerythropoietin expressed in transgenic plants. Int J Biol Macromol. 2015 Jan; 72:1111-6.
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Kittur FS, Hung CY, Darlington DE, Sane DC, Xie J. N-Glycosylation engineering of tobacco plants to produce asialoerythropoietin. Plant Cell Rep. 2012 Jul; 31(7):1233-43.
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Ochieng J, Warfield P, Green B. Interactions of gelatinases with soluble and immobilized fetuin and asialofetuin. Arch Biochem Biophys. 1995 Sep 10; 322(1):250-5.