"Clusterin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly conserved heterodimeric glycoprotein that is differentially expressed during many severe physiological disturbance states such as CANCER; APOPTOSIS; and various NEUROLOGICAL DISORDERS. Clusterin is ubiquitously expressed and appears to function as a secreted MOLECULAR CHAPERONE.
| Descriptor ID |
D051152
|
| MeSH Number(s) |
D12.776.395.207 D12.776.580.215
|
| Concept/Terms |
Clusterin- Clusterin
- SGP-2 Protein
- SGP 2 Protein
- Apolipoprotein J
- Complement Lysis Inhibitor
- Complement-Associated Protein SP-40,40
- Complement Associated Protein SP 40,40
- SP-40,40, Complement-Associated Protein
- Sulfated Glycoprotein 2
- Sulfated Glycoprotein-2
- Ionizing Radiation-Induced Protein-8
- Ionizing Radiation Induced Protein 8
- Radiation-Induced Protein-8, Ionizing
- XIP8 Protein
- X-Ray-Inducible Protein 8
- X Ray Inducible Protein 8
- Testosterone-Repressed Prostate Message-2 Protein
- Testosterone Repressed Prostate Message 2 Protein
- ApoJ Protein
- TRPM-2 Protein
- TRPM 2 Protein
- MAC393 Antigen
- SP 40,40 Protein
|
Below are MeSH descriptors whose meaning is more general than "Clusterin".
Below are MeSH descriptors whose meaning is more specific than "Clusterin".
This graph shows the total number of publications written about "Clusterin" by people in this website by year, and whether "Clusterin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clusterin" by people in Profiles.
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Huang MB, Gonzalez RR, Lillard J, Bond VC. Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells. Oncotarget. 2017 Feb 14; 8(7):11302-11315.
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Vaiopoulou A, Gazouli M, Papadopoulou A, Anagnostopoulos AK, Karamanolis G, Theodoropoulos GE, M'Koma A, Tsangaris GT. Serum protein profiling of adults and children with Crohn disease. J Pediatr Gastroenterol Nutr. 2015 Jan; 60(1):42-7.
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Humphries JM, Penno MA, Weiland F, Klingler-Hoffmann M, Zuber A, Boussioutas A, Ernst M, Hoffmann P. Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer. Biochim Biophys Acta. 2014 May; 1844(5):1051-8.
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Lee JH, Cheng R, Barral S, Reitz C, Medrano M, Lantigua R, Jim?nez-Velazquez IZ, Rogaeva E, St George-Hyslop PH, Mayeux R. Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals. Arch Neurol. 2011 Mar; 68(3):320-8.
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Corneveaux JJ, Myers AJ, Allen AN, Pruzin JJ, Ramirez M, Engel A, Nalls MA, Chen K, Lee W, Chewning K, Villa SE, Meechoovet HB, Gerber JD, Frost D, Benson HL, O'Reilly S, Chibnik LB, Shulman JM, Singleton AB, Craig DW, Van Keuren-Jensen KR, Dunckley T, Bennett DA, De Jager PL, Heward C, Hardy J, Reiman EM, Huentelman MJ. Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet. 2010 Aug 15; 19(16):3295-301.
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Strocchi P, Smith MA, Perry G, Tamagno E, Danni O, Pession A, Gaiba A, Dozza B. Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells. Neurobiol Aging. 2006 Nov; 27(11):1588-94.
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Nestlerode CS, Bunker CH, Sanghera DK, Aston CE, Ukoli FA, Kamboh MI. Apolipoprotein J polymorphisms and serum HDL cholesterol levels in African blacks. Hum Biol. 1999 Apr; 71(2):197-218.