nef Gene Products, Human Immunodeficiency Virus
"nef Gene Products, Human Immunodeficiency Virus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins encoded by the NEF GENES of the HUMAN IMMUNODEFICIENCY VIRUS.
| Descriptor ID |
D054311
|
| MeSH Number(s) |
D12.776.964.775.362.500 D12.776.964.775.562.760 D12.776.964.925.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "nef Gene Products, Human Immunodeficiency Virus".
Below are MeSH descriptors whose meaning is more specific than "nef Gene Products, Human Immunodeficiency Virus".
This graph shows the total number of publications written about "nef Gene Products, Human Immunodeficiency Virus" by people in this website by year, and whether "nef Gene Products, Human Immunodeficiency Virus" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2021 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "nef Gene Products, Human Immunodeficiency Virus" by people in Profiles.
-
Pushkarsky T, Ward A, Ivanov A, Lin X, Sviridov D, Nekhai S, Bukrinsky MI. Abundance of Nef and p-Tau217 in Brains of Individuals Diagnosed with HIV-Associated Neurocognitive Disorders Correlate with Disease Severance. Mol Neurobiol. 2022 Feb; 59(2):1088-1097.
-
Rivera-Ortiz J, Pla-Tenorio J, Cruz ML, Colon K, Perez-Morales J, Rodriguez JA, Martinez-Sicari J, Noel RJ. Blockade of beta adrenergic receptors protects the blood brain barrier and reduces systemic pathology caused by HIV-1 Nef protein. PLoS One. 2021; 16(11):e0259446.
-
Chompre G, Martinez-Orengo N, Cruz M, Porter JT, Noel RJ. TGF?RI antagonist inhibits HIV-1 Nef-induced CC chemokine family ligand 2 (CCL2) in the brain and prevents spatial learning impairment. J Neuroinflammation. 2019 Dec 11; 16(1):262.
-
Rivera J, Isidro RA, Loucil-Alicea RY, Cruz ML, Appleyard CB, Isidro AA, Chompre G, Colon-Rivera K, Noel RJ. Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood-brain-barrier permeability. PLoS One. 2019; 14(11):e0225760.
-
Huang MB, Gonzalez RR, Lillard J, Bond VC. Secretion modification region-derived peptide blocks exosome release and mediates cell cycle arrest in breast cancer cells. Oncotarget. 2017 Feb 14; 8(7):11302-11315.
-
Khan MB, Lang MJ, Huang MB, Raymond A, Bond VC, Shiramizu B, Powell MD. Nef exosomes isolated from the plasma of individuals with HIV-associated dementia (HAD) can induce A?(1-42) secretion in SH-SY5Y neural cells. J Neurovirol. 2016 Apr; 22(2):179-90.
-
Reszka-Blanco NJ, Sivaraman V, Zhang L, Su L. HIV-1 Env and Nef Cooperatively Contribute to Plasmacytoid Dendritic Cell Activation via CD4-Dependent Mechanisms. J Virol. 2015 Aug; 89(15):7604-11.
-
Shelton MN, Huang MB, Ali S, Johnson K, Roth W, Powell M, Bond V. Peptide-based identification of functional motifs and their binding partners. J Vis Exp. 2013 Jun 30; (76).
-
Chompre G, Cruz E, Maldonado L, Rivera-Amill V, Porter JT, Noel RJ. Astrocytic expression of HIV-1 Nef impairs spatial and recognition memory. Neurobiol Dis. 2013 Jan; 49:128-36.
-
Campbell PE, Isayev O, Ali SA, Roth WW, Huang MB, Powell MD, Leszczynski J, Bond VC. Validation of a novel secretion modification region (SMR) of HIV-1 Nef using cohort sequence analysis and molecular modeling. J Mol Model. 2012 Oct; 18(10):4603-13.