Vimentin

"Vimentin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An intermediate filament protein found in most differentiating cells, in cells grown in tissue culture, and in certain fully differentiated cells. Its insolubility suggests that it serves a structural function in the cytoplasm. MW 52,000.

Descriptor ID	D014746
MeSH Number(s)	D05.750.078.593.900 D12.776.220.475.900
Concept/Terms	Vimentin Vimentin

Below are MeSH descriptors whose meaning is more general than "Vimentin".

Chemicals and Drugs [D]
Macromolecular Substances [D05]
Polymers [D05.750]
Biopolymers [D05.750.078]
Intermediate Filament Proteins [D05.750.078.593]
Vimentin [D05.750.078.593.900]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Cytoskeletal Proteins [D12.776.220]
Intermediate Filament Proteins [D12.776.220.475]
Vimentin [D12.776.220.475.900]

Below are MeSH descriptors whose meaning is related to "Vimentin".

Below are MeSH descriptors whose meaning is more specific than "Vimentin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Vimentin" by people in this website by year, and whether "Vimentin" was a major or minor topic of these publications.

Bar chart showing 23 publications over 15 distinct years, with a maximum of 3 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2004	0	1	1
2005	0	1	1
2006	0	2	2
2008	0	1	1
2010	0	1	1
2011	0	1	1
2012	1	1	2
2013	0	2	2
2015	0	2	2
2018	1	1	2
2021	0	1	1
2022	0	2	2
2024	2	1	3
2025	1	0	1

Below are the most recent publications written about "Vimentin" by people in Profiles.

Hou C, Yu F, Cao C, Wang T, Pan Z, Zhong M, Liu X, Yao X, Zhang K, Yang Z, Guo J. Aurora B maintains spherical shape of mitotic cells via simultaneously stabilizing myosin II and vimentin. J Mol Cell Biol. 2025 Dec 29; 17(5).

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Alves CC, Lewis J, Antunes DA, Donadi EA. The Role of Vimentin Peptide Citrullination in the Structure and Dynamics of HLA-DRB1 Rheumatoid Arthritis Risk-Associated Alleles. Int J Mol Sci. 2024 Dec 24; 26(1).

View in: PubMed
Rorex C, Cardona SM, Church KA, Rodriguez D, Vanegas D, Saldivar R, Faz B, Cardona AE. Astrogliosis in the GFAP-CreERT2:Rosa26iDTR Mouse Model Does Not Exacerbate Retinal Microglia Activation or M?ller Cell Gliosis under Hypoxic Conditions. Biomolecules. 2024 May 10; 14(5).

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Ni WJ, Li ZL, Wen XL, Ji JL, Liu H, Yin Q, Jiang LY, Zhang YL, Wen Y, Tang TT, Jiang W, Lv LL, Gan WH, Liu BC, Wang B. HIF-1a and adaptor protein LIM and senescent cell antigen-like domains protein 1 axis promotes tubulointerstitial fibrosis by interacting with vimentin in angiotensin II-induced hypertension. Br J Pharmacol. 2024 Sep; 181(17):3098-3117.

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Huang MB, Brena D, Wu JY, Roth WW, Owusu S, Bond VC. Novel secretion modification region (SMR) peptide exhibits anti-metastatic properties in human breast cancer cells. Sci Rep. 2022 08 01; 12(1):13204.

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Hu F, Peng Y, Chang S, Luo X, Yuan Y, Zhu X, Xu Y, Du K, Chen Y, Deng S, Yu F, Feng X, Fan X, Ashktorab H, Smoot D, Meltzer SJ, Li S, Wei Y, Zhang X, Jin Z. Vimentin binds to a novel tumor suppressor protein, GSPT1-238aa, encoded by circGSPT1 with a selective encoding priority to halt autophagy in gastric carcinoma. Cancer Lett. 2022 10 01; 545:215826.

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Messeha SS, Zarmouh NO, Soliman KFA. Polyphenols Modulating Effects of PD-L1/PD-1 Checkpoint and EMT-Mediated PD-L1 Overexpression in Breast Cancer. Nutrients. 2021 May 19; 13(5).

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Maskarinec G, Ju D, Fong J, Horio D, Chan O, Loo LWM, Hernandez BY. Mammographic density and breast tissue expression of inflammatory markers, growth factors, and vimentin. BMC Cancer. 2018 Nov 29; 18(1):1191.

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Odero-Marah V, Hawsawi O, Henderson V, Sweeney J. Epithelial-Mesenchymal Transition (EMT) and Prostate Cancer. Adv Exp Med Biol. 2018; 1095:101-110.

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Miklossy G, Youn UJ, Yue P, Zhang M, Chen CH, Hilliard TS, Paladino D, Li Y, Choi J, Sarkaria JN, Kawakami JK, Wongwiwatthananukit S, Chen Y, Sun D, Chang LC, Turkson J. Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin a-2 Expression, and Induce Antitumor Effects against Human Glioma. J Med Chem. 2015 Oct 08; 58(19):7734-48.

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