Serum Amyloid P-Component

"Serum Amyloid P-Component" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Amyloid P component is a small, non-fibrillar glycoprotein found in normal serum and in all amyloid deposits. It has a pentagonal (pentaxin) structure. It is an acute phase protein, modulates immunologic responses, inhibits ELASTASE, and has been suggested as an indicator of LIVER DISEASE.

Descriptor ID	D000683
MeSH Number(s)	D12.776.049.407.875 D12.776.124.050.730 D12.776.395.690
Concept/Terms	Serum Amyloid P-Component Serum Amyloid P-Component Amyloid P-Component, Serum P-Component, Serum Amyloid Serum Amyloid P Component Amyloid P Component P Component, Amyloid

Below are MeSH descriptors whose meaning is more general than "Serum Amyloid P-Component".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Amyloid [D12.776.049]
Amyloidogenic Proteins [D12.776.049.407]
Serum Amyloid P-Component [D12.776.049.407.875]
Blood Proteins [D12.776.124]
Acute-Phase Proteins [D12.776.124.050]
Serum Amyloid P-Component [D12.776.124.050.730]
Glycoproteins [D12.776.395]
Serum Amyloid P-Component [D12.776.395.690]

Below are MeSH descriptors whose meaning is related to "Serum Amyloid P-Component".

Below are MeSH descriptors whose meaning is more specific than "Serum Amyloid P-Component".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Serum Amyloid P-Component" by people in this website by year, and whether "Serum Amyloid P-Component" was a major or minor topic of these publications.

Bar chart showing 10 publications over 10 distinct years, with a maximum of 1 publications in 1995 and 2000 and 2002 and 2005 and 2009 and 2012 and 2015 and 2016 and 2017 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
2000	1	0	1
2002	1	0	1
2005	0	1	1
2009	0	1	1
2012	1	0	1
2015	1	0	1
2016	1	0	1
2017	0	1	1
2022	0	1	1

Below are the most recent publications written about "Serum Amyloid P-Component" by people in Profiles.

Zen?n-Mel?ndez CN, Carrasquillo Carri?n K, Cantres Rosario Y, Roche Lima A, Mel?ndez LM. Inhibition of Cathepsin B and SAPC Secreted by HIV-Infected Macrophages Reverses Common and Unique Apoptosis Pathways. J Proteome Res. 2022 02 04; 21(2):301-312.

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Ainsworth S, Ketter PM, Yu JJ, Grimm RC, May HC, Cap AP, Chambers JP, Guentzel MN, Arulanandam BP. Vaccination with a live attenuated Acinetobacter baumannii deficient in thioredoxin provides protection against systemic Acinetobacter infection. Vaccine. 2017 06 08; 35(26):3387-3394.

View in: PubMed
Ketter P, Yu JJ, Cap AP, Forsthuber T, Arulanandam B. Pentraxin 3: an immune modulator of infection and useful marker for disease severity assessment in sepsis. Expert Rev Clin Immunol. 2016; 12(5):501-7.

View in: PubMed
Zungsontiporn N, Ndhlovu LC, Mitchell BI, Stein JH, Kallianpur KJ, Nakamoto B, Keating SM, Norris PJ, Souza SA, Shikuma CM, Chow DC. Serum amyloid P (SAP) is associated with impaired brachial artery flow-mediated dilation in chronically HIV-1 infected adults on stable antiretroviral therapy. HIV Clin Trials. 2015 11; 16(6):228-35.

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Iwata A, Miura S, Tanaka T, Ike A, Sugihara M, Nishikawa H, Kawamura A, Saku K. Plasma pentraxin-3 levels are associated with coronary plaque vulnerability and are decreased by statin. Coron Artery Dis. 2012 Aug; 23(5):315-21.

View in: PubMed
Sugihara M, Miura S, Takamiya Y, Kiya Y, Arimura T, Iwata A, Kawamura A, Nishikawa H, Uehara Y, Saku K. Safety and efficacy of antihypertensive therapy with add-on angiotensin II type 1 receptor blocker after successful coronary stent implantation. Hypertens Res. 2009 Jul; 32(7):625-30.

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Mineo C, Gormley AK, Yuhanna IS, Osborne-Lawrence S, Gibson LL, Hahner L, Shohet RV, Black S, Salmon JE, Samols D, Karp DR, Thomas GD, Shaul PW. FcgammaRIIB mediates C-reactive protein inhibition of endothelial NO synthase. Circ Res. 2005 Nov 25; 97(11):1124-31.

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Shi J, Perry G, Berridge MS, Aliev G, Siedlak SL, Smith MA, LaManna JC, Friedland RP. Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice. J Nucl Med. 2002 Aug; 43(8):1044-51.

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Friedland RP, Shi J, Lamanna JC, Smith MA, Perry G. Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's disease. Ann N Y Acad Sci. 2000 Apr; 903:123-8.

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Kindy MS, King AR, Perry G, de Beer MC, de Beer FC. Association of apolipoprotein E with murine amyloid A protein amyloid. Lab Invest. 1995 Oct; 73(4):469-75.

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