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Firas Kobaissy, Ms, PhD

TitleAssociate Director, Center for Neurotrauma, Multiomics & Biomarkers
Faculty RankProfessor
InstitutionMorehouse School of Medicine
Address720 Westview Dr SW
Atlanta GA 30310
Email
ORCID ORCID Icon0000-0002-5008-6944 Additional info
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    Collapse Biography 
    Collapse education and training
    University of Florida, Gainesville, FlPhD08/2007Neuroscience
    American University of Beirut, Beirut, LebanonMS08/2002Immunology

    Collapse Overview 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Al Zein M, Akomolafe AF, Mahmood FR, Khrayzat A, Sahebkar A, Pintus G, Kobeissy F, Eid AH. Leptin is a potential biomarker of childhood obesity and an indicator of the effectiveness of weight-loss interventions. Obes Rev. 2024 Jul 23; e13807. PMID: 39044542.
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    2. Sanni A, Hakim MA, Goli M, Adeniyi M, Talih F, Lanuzza B, Kobeissy F, Plazzi G, Moresco M, Mondello S, Ferri R, Mechref Y. Serum N-Glycan Profiling of Patients with Narcolepsy Type 1 Using LC-MS/MS. ACS Omega. 2024 Jul 30; 9(30):32628-32638. PMID: 39100283.
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    3. Seplovich G, Bouchi Y, de Rivero Vaccari JP, Pareja JCM, Reisner A, Blackwell L, Mechref Y, Wang KK, Tyndall JA, Tharakan B, Kobeissy F. Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease. Neural Regen Res. 2025 Jun 01; 20(6):1644-1664. PMID: 39104096.
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    4. Saad H, El Baba B, Tfaily A, Kobeissy F, Gonzalez JG, Refai D, Rodts GR, Mustroph C, Gimbel D, Grossberg J, Barrow DL, Gary MF, Alawieh AM. Complement-dependent neuroinflammation in spinal cord injury: from pathology to therapeutic implications. Neural Regen Res. 2025 May 01; 20(5):1324-1335. PMID: 38845224.
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    5. Reisner A, Zohdy YM, Chern JJ, Blackwell LS, Lepard JR, Alawieh A, Verma MS, Kobeissy F, Mulugeta MG, Tyndall JA, Klein BJ, Fariyike OA, Mannix R, Munoz Pareja JC, Wang KK. The utility of biomarkers in traumatic brain injuries in children: opportunities and challenges. J Neurosurg Pediatr. 2024 May 17; 34(2):199-203. PMID: 38759233.
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    6. Johnson JR, Martini RN, Yuan YC, Woods-Burnham L, Walker M, Ortiz-Hernandez GL, Kobeissy F, Galloway D, Gaddy A, Oguejiofor C, Allen B, Lewis D, Davis MB, Kimbro KS, Yates CC, Murphy AB, Kittles RA. 1,25-Dihydroxyvitamin D3 Suppresses Prognostic Survival Biomarkers Associated with Cell Cycle and Actin Organization in a Non-Malignant African American Prostate Cell Line. Biology (Basel). 2024 May 15; 13(5). PMID: 38785827.
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    7. Wang KKW, Barton DJ, McQuillan LE, Kobeissy F, Cai G, Xu H, Yang Z, Trifilio E, Williamson JB, Rubenstein R, Robertson CS, Wagner AK. Parallel Cerebrospinal Fluid and Serum Temporal Profile Assessment of Axonal Injury Biomarkers Neurofilament-Light Chain and Phosphorylated Neurofilament-Heavy Chain: Associations With Patient Outcome in Moderate-Severe Traumatic Brain Injury. J Neurotrauma. 2024 Jul; 41(13-14):1609-1627. PMID: 38588256.
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    8. Abou-Abbass H, El Sheikh WG, Bizri M, Tamim H, Al-Hajj S, Karout L, Allouch F, Chehade R, Ghannam M, Fares Y, Nasser Z, Harati H, Kobeissy F. Cultural assimilation of adult Syrian refugees in Lebanon: Effect modification by religiosity and sex on the relation between cultural adversities and common mental health disorders. Psychol Trauma. 2024 Apr 18. PMID: 38635208.
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    9. Abbasloo E, Esmaeili-Mahani S, Kobeissy F, Thomas TC. Evidence for the induction of analgesic cross-tolerance between opioid and apelin/APJ systems in male rats. J Stud Alcohol Drugs. 2024 Mar 22. PMID: 38517751.
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    10. Dakroub F, Kobeissy F, Mondello S, Yang Z, Xu H, Sura L, Rossignol C, Albayram M, Rajderkar D, Wang K, Weiss MD. MicroRNAs as biomarkers of brain injury in neonatal encephalopathy: an observational cohort study. Sci Rep. 2024 Mar 19; 14(1):6645. PMID: 38503820.
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    11. Wang B, Pan X, Teng IT, Li X, Kobeissy F, Wu ZY, Zhu J, Cai G, Yan H, Yan X, Liang M, Yu F, Lu J, Yang Z, Biondi E, Haskins W, Cao YC, Benner SA, Tan W, Wang KK. Functional Selection of Tau Oligomerization-Inhibiting Aptamers. Angew Chem Int Ed Engl. 2024 Apr 24; 63(18):e202402007. PMID: 38407551.
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    12. Wang B, Kobeissy F, Golpich M, Cai G, Li X, Abedi R, Haskins W, Tan W, Benner SA, Wang KKW. Aptamer Technologies in Neuroscience, Neuro-Diagnostics and Neuro-Medicine Development. Molecules. 2024 Mar 02; 29(5). PMID: 38474636.
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    13. Yaacoub S, Boudaka A, AlKhatib A, Pintus G, Sahebkar A, Kobeissy F, Eid AH. The pharmaco-epigenetics of hypertension: a focus on microRNA. Mol Cell Biochem. 2024 Feb 29. PMID: 38424404.
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    14. Bhomia M, Feng Y, Deleon P, Robertson CS, Kobeissy F, Wang KK, Knollmann-Ritschel B. Transcriptomic Signatures of Neuronally Derived Extracellular Vesicles Reveal the Presence of Olfactory Receptors in Clinical Samples from Traumatic Brain Injury Patients. Int J Mol Sci. 2024 Feb 28; 25(5). PMID: 38474024.
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    15. Shaito AA, Omairi I, Al-Thani N, Seglab F, Ad-Darwish E, Kobeissy F, Nasreddine S. Determination of Medicago orbicularis Antioxidant, Antihemolytic, and Anti-Cancerous Activities and Its Augmentation of Cisplatin-Induced Cytotoxicity in A549 Lung Cancer Cells. Plants (Basel). 2024 Feb 02; 13(3). PMID: 38337975.
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    16. Trivedi D, Forssten MP, Cao Y, Ismail AM, Czeiter E, Amrein K, Kobeissy F, Wang KKW, DeSoucy E, Buki A, Mohseni S. Screening Performance of S100 Calcium-Binding Protein B, Glial Fibrillary Acidic Protein, and Ubiquitin C-Terminal Hydrolase L1 for Intracranial Injury Within Six Hours of Injury and Beyond. J Neurotrauma. 2024 Feb; 41(3-4):349-358. PMID: 38115670.
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    17. Kobeissy F, Arja RD, Munoz JC, Shear DA, Gilsdorf J, Zhu J, Yadikar H, Haskins W, Tyndall JA, Wang KK. The game changer: UCH-L1 and GFAP-based blood test as the first marketed in vitro diagnostic test for mild traumatic brain injury. Expert Rev Mol Diagn. 2024; 24(1-2):67-77. PMID: 38275158.
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    18. Lember LM, Ntikas M, Mondello S, Wilson L, Di Virgilio TG, Hunter AM, Kobeissy F, Mechref Y, Donaldson DI, Ietswaart M. The Use of Biofluid Markers to Evaluate the Consequences of Sport-Related Subconcussive Head Impact Exposure: A Scoping Review. Sports Med Open. 2024 Jan 25; 10(1):12. PMID: 38270708.
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    19. Kommireddy RS, Mehra S, Pompilus M, Arja RD, Zhu T, Yang Z, Fu Y, Zhu J, Kobeissy F, Wang KKW, Febo M. Functional connectivity, tissue microstructure and T2 at 11.1 Tesla distinguishes neuroadaptive differences in two traumatic brain injury models in rats: A Translational Outcomes Project in NeuroTrauma (TOP-NT) UG3 phase study. bioRxiv. 2024 Jan 19. PMID: 38168381.
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    20. Morris AR, Gudenschwager Basso EK, Gutierrez-Monreal MA, Arja RD, Kobeissy FH, Janus CG, Wang KKW, Zhu J, Liu AC. Lifelong Chronic Sleep Disruption in a Mouse Model of Traumatic Brain Injury. Neurotrauma Rep. 2024; 5(1):61-73. PMID: 38288298.
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    21. Fardoun M, Kobeissy F, Eid AH. Estrogen Receptor and the Gender Bias in Raynaud's Phenomenon. Curr Med Chem. 2024; 31(2):133-137. PMID: 36803760.
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    22. Aqel S, Al-Thani N, Haider MZ, Abdelhady S, Al Thani AA, Kobeissy F, Shaito AA. Biomaterials in Traumatic Brain Injury: Perspectives and Challenges. Biology (Basel). 2023 Dec 29; 13(1). PMID: 38248452.
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    23. Kobeissy F, Goli M, Yadikar H, Shakkour Z, Kurup M, Haidar MA, Alroumi S, Mondello S, Wang KK, Mechref Y. Advances in neuroproteomics for neurotrauma: unraveling insights for personalized medicine and future prospects. Front Neurol. 2023; 14:1288740. PMID: 38073638.
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    24. Morris AR, Gudenschwager Basso EK, Gutierrez-Monreal MA, Arja RD, Kobeissy FH, Janus CG, Wang KKW, Zhu J, Liu AC. Sleep Disruption in a Mouse Model of Chronic Traumatic Brain Injury. bioRxiv. 2023 Nov 14. PMID: 38014315.
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    25. Halabi R, Dakroub F, Haider MZ, Patel S, Amhaz NA, Reslan MA, Eid AH, Mechref Y, Darwiche N, Kobeissy F, Omeis I, Shaito AA. Unveiling a Biomarker Signature of Meningioma: The Need for a Panel of Genomic, Epigenetic, Proteomic, and RNA Biomarkers to Advance Diagnosis and Prognosis. Cancers (Basel). 2023 Nov 09; 15(22). PMID: 38001599.
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    26. Munoz Pareja JC, de Rivero Vaccari JP, Chavez MM, Kerrigan M, Pringle C, Guthrie K, Swaby K, Coto J, Kobeissy F, Avery KL, Ghosh S, Dhanashree R, Shanmugham P, Lautenslager LA, Faulkenberry S, Pareja Zabala MC, Al Fakhri N, Loor-Torres R, Governale LS, Blatt JE, Gober J, Perez PK, Solano J, McCrea H, Thorson C, O'Phelan KH, Keane RW, Dietrich WD, Wang KK. Prognostic and Diagnostic Utility of Serum Biomarkers in Pediatric Traumatic Brain Injury. J Neurotrauma. 2024 Jan; 41(1-2):106-122. PMID: 37646421.
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    27. Atashi M, Reyes CDG, Sandilya V, Purba W, Ahmadi P, Hakim MA, Kobeissy F, Plazzi G, Moresco M, Lanuzza B, Ferri R, Mechref Y. LC-MS/MS Quantitation of HILIC-Enriched N-glycopeptides Derived from Low-Abundance Serum Glycoproteins in Patients with Narcolepsy Type 1. Biomolecules. 2023 Oct 28; 13(11). PMID: 38002271.
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    28. Al Zein M, Zein O, Diab R, Dimachkie L, Sahebkar A, Al-Asmakh M, Kobeissy F, Eid AH. Intermittent fasting favorably modulates adipokines and potentially attenuates atherosclerosis. Biochem Pharmacol. 2023 Dec; 218:115876. PMID: 37871879.
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    29. Al-Hajj S, Farran SH, Dekmak B, Hneiny L, Abou Abbas H, Hassoun A, Youness N, Ghalayini S, Abou Khalil N, Lecky F, Shahjouieh S, Ghamlouche L, Nasrallah Z, Kobeissy F. Pediatric Traumatic Brain Injury in the Middle East and North Africa Region: A Systematic Review and Meta-Analysis to Assess Characteristics, Mechanisms, and Risk Factors. Neurotrauma Rep. 2023; 4(1):693-714. PMID: 37908319.
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    30. Capuz A, Osien S, Cardon T, Karnoub MA, Aboulouard S, Raffo-Romero A, Duhamel M, Cizkova D, Trerotola M, Devos D, Kobeissy F, F VA, Bonnefond A, Fournier I, Rodet F, Salzet M. Correction: Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome. Cell Death Dis. 2023 Oct 13; 14(10):677. PMID: 37833264.
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    31. Wisztorski M, Aboulouard S, Roussel L, Duhamel M, Saudemont P, Cardon T, Narducci F, Robin YM, Lemaire AS, Bertin D, Hajjaji N, Kobeissy F, Leblanc E, Fournier I, Salzet M. Fallopian tube lesions as potential precursors of early ovarian cancer: a comprehensive proteomic analysis. Cell Death Dis. 2023 Sep 30; 14(9):644. PMID: 37775701.
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    32. Rammal G, Fahs A, Kobeissy F, Mechref Y, Zhao J, Zhu R, Diab-Assaf M, Saab R, Ghayad SE. Correction to: Proteomic Profiling of Rhabdomyosarcoma-Derived Exosomes Yield Insights into Their Functional Role in Paracrine Signaling. J Proteome Res. 2023 Nov 03; 22(11):3660-3661. PMID: 37769164.
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    33. El-Baba C, Ayache Z, Goli M, Hayar B, Kawtharani Z, Pisano C, Kobeissy F, Mechref Y, Darwiche N. The Antitumor Effect of the DNA Polymerase Alpha Inhibitor ST1926 in Glioblastoma: A Proteomics Approach. Int J Mol Sci. 2023 Sep 14; 24(18). PMID: 37762371.
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    34. Li C, Chen S, Siedhoff HR, Grant D, Liu P, Balderrama A, Jackson M, Zuckerman A, Greenlief CM, Kobeissy F, Wang KW, DePalma RG, Cernak I, Cui J, Gu Z. Low-intensity open-field blast exposure effects on neurovascular unit ultrastructure in mice. Acta Neuropathol Commun. 2023 Sep 06; 11(1):144. PMID: 37674234.
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    35. Abbasloo E, Khaksari M, Sanjari M, Kobeissy F, Thomas TC. Carvacrol decreases blood-brain barrier permeability post-diffuse traumatic brain injury in rats. Sci Rep. 2023 Sep 04; 13(1):14546. PMID: 37666857.
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    36. Buh FC, Sumbele IUN, Maas AIR, Motah M, Pattisapu JV, Youm E, Meh BK, Kobeissy FH, Wang KW, Hutchinson PJA, Taiwe GS. Traumatic Brain Injury in Cameroon: A Prospective Observational Study in a Level I Trauma Centre. Medicina (Kaunas). 2023 Aug 28; 59(9). PMID: 37763678.
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    37. Capuz A, Osien S, Cardon T, Karnoub MA, Aboulouard S, Raffo-Romero A, Duhamel M, Cizkova D, Trerotola M, Devos D, Kobeissy F, Vanden Abeele F, Bonnefond A, Fournier I, Rodet F, Salzet M. Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome. Cell Death Dis. 2023 Aug 16; 14(8):526. PMID: 37587118.
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    38. Pischiutta F, Cavaleiro H, Caruso E, Tribuzio F, Di Marzo N, Moro F, Kobeissy F, Wang KK, Salgado AJ, Zanier ER. A novel organotypic cortical slice culture model for traumatic brain injury: molecular changes induced by injury and mesenchymal stromal cell secretome treatment. Front Cell Neurosci. 2023; 17:1217987. PMID: 37534042.
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    39. Mrad Y, El Jammal R, Hajjar H, Alturk S, Salah H, Chehade HD, Dandash F, Mallah Z, Kobeissy F, Habib A, Hamade E, Obeid M. Lestaurtinib (CEP-701) reduces the duration of limbic status epilepticus in periadolescent rats. Epilepsy Res. 2023 Sep; 195:107198. PMID: 37467703.
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    40. Mohamed WMY, Kobeissy F, Mondello S. Editorial: Biomarkers in neurology, volume II. Front Neurol. 2023; 14:1244536. PMID: 37503511.
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    41. Yang Z, Apiliogullari S, Fu Y, Istanbouli A, Kaur S, Jabbal IS, Moghieb A, Irfan Z, Patterson RL, Kurup M, Morrow L, Cohn M, Zhang Z, Zhu J, Hayes RL, Bramlett HM, Bullock MR, Dietrich WD, Wang MY, Kobeissy F, Wang KW. Association between Cerebrospinal Fluid and Serum Biomarker Levels and Diagnosis, Injury Severity, and Short-Term Outcomes in Patients with Acute Traumatic Spinal Cord Injury. Diagnostics (Basel). 2023 May 22; 13(10). PMID: 37238298.
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    42. Jammoul M, Jammoul D, Wang KK, Kobeissy F, Depalma RG. Traumatic Brain Injury and Opioids: Twin Plagues of the Twenty-First Century. Biol Psychiatry. 2024 Jan 01; 95(1):6-14. PMID: 37217015.
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    43. Aboukhater D, Morad B, Nasrallah N, Nasser SA, Sahebkar A, Kobeissy F, Boudaka A, Eid AH. Inflammation and hypertension: Underlying mechanisms and emerging understandings. J Cell Physiol. 2023 Jun; 238(6):1148-1159. PMID: 37039489.
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    44. Capuz A, Osien S, Karnoub MA, Aboulouard S, Laurent E, Coyaud E, Raffo-Romero A, Duhamel M, Bonnefond A, Derhourhi M, Trerotola M, El Yazidi-Belkoura I, Devos D, Zilkova M, Kobeissy F, Vanden Abeele F, Fournier I, Cizkova D, Rodet F, Salzet M. Astrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion. Cell Death Dis. 2023 Apr 04; 14(4):237. PMID: 37015912.
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    45. Yue JK, Kobeissy FH, Jain S, Sun X, Phelps RRL, Korley FK, Gardner RC, Ferguson AR, Huie JR, Schneider ALC, Yang Z, Xu H, Lynch CE, Deng H, Rabinowitz M, Vassar MJ, Taylor SR, Mukherjee P, Yuh EL, Markowitz AJ, Puccio AM, Okonkwo DO, Diaz-Arrastia R, Manley GT, Wang KKW. Neuroinflammatory Biomarkers for Traumatic Brain Injury Diagnosis and Prognosis: A TRACK-TBI Pilot Study. Neurotrauma Rep. 2023; 4(1):171-183. PMID: 36974122.
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    46. Abbasloo E, Amiresmaili S, Shirazpour S, Khaksari M, Kobeissy F, Thomas TC. Satureja khuzistanica Jamzad essential oil and pure carvacrol attenuate TBI-induced inflammation and apoptosis via NF-?B and caspase-3 regulation in the male rat brain. Sci Rep. 2023 Mar 23; 13(1):4780. PMID: 36959464.
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    47. Slika H, Mansour H, Nasser SA, Shaito A, Kobeissy F, Orekhov AN, Pintus G, Eid AH. Epac as a tractable therapeutic target. Eur J Pharmacol. 2023 Apr 15; 945:175645. PMID: 36894048.
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    48. Sanni A, Goli M, Zhao J, Wang J, Barsa C, El Hayek S, Talih F, Lanuzza B, Kobeissy F, Plazzi G, Moresco M, Mondello S, Ferri R, Mechref Y. LC-MS/MS-Based Proteomics Approach for the Identification of Candidate Serum Biomarkers in Patients with Narcolepsy Type 1. Biomolecules. 2023 Feb 23; 13(3). PMID: 36979356.
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    49. Pandya JD, Musyaju S, Modi HR, Cao Y, Flerlage WJ, Huynh L, Kociuba B, Visavadiya NP, Kobeissy F, Wang K, Gilsdorf JS, Scultetus AH, Shear DA. Comprehensive evaluation of mitochondrial redox profile, calcium dynamics, membrane integrity and apoptosis markers in a preclinical model of severe penetrating traumatic brain injury. Free Radic Biol Med. 2023 Mar; 198:44-58. PMID: 36758906.
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    50. El Husseiny J, Farran SH, El Sheikh WG, Yehya Y, El Hayek S, El Husseiny H, Hneiny L, Shahjouei S, Sabra M, Kobeissy F. Posttraumatic stress disorder among the Lebanese population and Syrian refugees: A systematic review. Psychol Trauma. 2023 Oct; 15(7):1102-1114. PMID: 36689379.
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    51. Yadikar H, Johnson C, Pafundi N, Nguyen L, Kurup M, Torres I, Al-Enezy A, Yang Z, Yost R, Kobeissy FH, Wang KKW. Neurobiochemical, Peptidomic, and Bioinformatic Approaches to Characterize Tauopathy Peptidome Biomarker Candidates in Experimental Mouse Model of Traumatic Brain Injury. Mol Neurobiol. 2023 Apr; 60(4):2295-2319. PMID: 36635478.
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    52. Hamze K, Abdallah RH, Younis NK, Fardoun M, Darwiche N, Kobeissy F, Iratni R, Bouhadir K, Eid AH. 2-Nucleobase-substituted 4,6-Diaminotriazine Analogs: Synthesis and Anti-cancer Activity in 5-Fluorouracil-sensitive and Resistant Colorectal Cancer Cells. Curr Med Chem. 2023; 30(26):3032-3049. PMID: 36111761.
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    53. Ibeh S, Bakkar NZ, Ahmad F, Nwaiwu J, Barsa C, Mekhjian S, Reslan MA, Eid AH, Harati H, Nabha S, Mechref Y, El-Yazbi AF, Kobeissy F. High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury. Life Sci. 2023 Feb 01; 314:121316. PMID: 36565814.
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    54. Bentley SA, Ahmad S, Kobeissy FH, Toklu HZ. Concomitant Guillain-Barré Syndrome and COVID-19: A Meta-Analysis of Cases. Medicina (Kaunas). 2022 Dec 13; 58(12). PMID: 36557036.
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    55. Kattan D, Barsa C, Mekhijian S, Shakkour Z, Jammoul M, Doumit M, Zabala MCP, Darwiche N, Eid AH, Mechref Y, Wang KK, de Rivero Vaccari JP, Munoz Pareja JC, Kobeissy F. Inflammasomes as biomarkers and therapeutic targets in traumatic brain injury and related-neurodegenerative diseases: A comprehensive overview. Neurosci Biobehav Rev. 2023 Jan; 144:104969. PMID: 36423707.
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    56. Fardoun M, Mondello S, Kobeissy F, Eid AH. G protein estrogen receptor as a potential therapeutic target in Raynaud's phenomenon. Front Pharmacol. 2022; 13:1061374. PMID: 36438809.
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    57. Peng W, Kobeissy F, Mondello S, Barsa C, Mechref Y. MS-based glycomics: An analytical tool to assess nervous system diseases. Front Neurosci. 2022; 16:1000179. PMID: 36408389.
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    58. Al Hariri M, Zgheib H, Abi Chebl K, Azar M, Hitti E, Bizri M, Rizk J, Kobeissy F, Mufarrij A. Assessing the psychological impact of Beirut Port blast: A cross-sectional study. Medicine (Baltimore). 2022 Oct 14; 101(41):e31117. PMID: 36253992.
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    59. Geagea L, Ghanimé PM, El Hayek S, Kobeissy F, Tamim H, Elbejjani M, Talih F. Assessing cognitive behavioral therapy for insomnia in individuals with cannabis use disorder utilizing actigraphy and serum biomarkers: A pilot study. Sleep Med. 2022 Dec; 100:434-441. PMID: 36244318.
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    60. El Hayek SA, Shatila MA, Adnan JA, Geagea LE, Kobeissy F, Talih FR. Is there a therapeutic potential in combining bupropion and naltrexone in schizophrenia? Expert Rev Neurother. 2022 Sep; 22(9):737-749. PMID: 36093756.
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    61. Younis NK, Roumieh R, Bassil EP, Ghoubaira JA, Kobeissy F, Eid AH. Nanoparticles: Attractive tools to treat colorectal cancer. Semin Cancer Biol. 2022 Nov; 86(Pt 2):1-13. PMID: 36028154.
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    62. Yang Z, Arja RD, Zhu T, Sarkis GA, Patterson RL, Romo P, Rathore DS, Moghieb A, Abbatiello S, Robertson CS, Haskins WE, Kobeissy F, Wang KKW. Characterization of Calpain and Caspase-6-Generated Glial Fibrillary Acidic Protein Breakdown Products Following Traumatic Brain Injury and Astroglial Cell Injury. Int J Mol Sci. 2022 Aug 11; 23(16). PMID: 36012232.
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    63. Habashy KJ, Ahmad F, Ibeh S, Mantash S, Kobeissy F, Issa H, Habis R, Tfaily A, Nabha S, Harati H, Reslan MA, Yehya Y, Barsa C, Shaito A, Zibara K, El-Yazbi AF, Kobeissy FH. Western and ketogenic diets in neurological disorders: can you tell the difference? Nutr Rev. 2022 Jul 07; 80(8):1927-1941. PMID: 35172003.
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    64. Burkle FM, Hadley KS, Ridge LL, Herman JK, Kobeissy FH. Delayed-Onset Neuropathological Complications From a Foramen Magnum and Occipital Crest Focused TBI of the Vietnam War and Other Conflicts: Part III, Critique of Existing TBI Criteria and Their Operational Controversies. Mil Med. 2022 Jul 01; 187(7-8):e933-e937. PMID: 34632521.
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    65. Burkle FM, Hadley KS, Ridge LL, Herman JK, Kobeissy FH. Delayed-Onset Neuropathological Complications From a Foramen Magnum and Occipital Crest Focused Traumatic Brain Injury of the Vietnam War and Other Conflicts: Part I, Case Report. Mil Med. 2022 Jul 01; 187(7-8):e921-e925. PMID: 34632519.
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    66. Burkle FM, Hadley KS, Ridge LL, Herman JK, Kobeissy FH. Delayed-Onset Neuropathological Complications From a Foramen Magnum and Occipital Crest-Focused Traumatic Brain Injury of the Vietnam War and Other Conflicts: Part II, Research Analysis. Mil Med. 2022 Jul 01; 187(7-8):e926-e932. PMID: 34632516.
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    67. AlKahlout A, Fardoun M, Mesmar J, Abdallah R, Badran A, Nasser SA, Baydoun S, Kobeissy F, Shaito A, Iratni R, Muhammad K, Baydoun E, Eid AH. Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells. Front Oncol. 2022; 12:922196. PMID: 35847867.
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    68. Dabbish AM, Abdelzaher HM, Abohawya M, Shamma S, Mahmoud YH, Maged A, Manaa M, Hassany M, Kobeissy F, Bazgir O, El-Fawal H, Azzazy HME, Abdelnaser A. Prognostic MicroRNA Panel for HCV-Associated HCC: Integrating Computational Biology and Clinical Validation. Cancers (Basel). 2022 Jun 21; 14(13). PMID: 35804809.
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    69. Mondello S, Sandner V, Goli M, Czeiter E, Amrein K, Kochanek PM, Gautam S, Cho BG, Morgan R, Nehme A, Fiumara G, Eid AH, Barsa C, Haidar MA, Buki A, Kobeissy FH, Mechref Y. Exploring serum glycome patterns after moderate to severe traumatic brain injury: A prospective pilot study. EClinicalMedicine. 2022 Aug; 50:101494. PMID: 35755600.
      Citations:    
    70. Haidar MA, Shakkour Z, Reslan MA, Al-Haj N, Chamoun P, Habashy K, Kaafarani H, Shahjouei S, Farran SH, Shaito A, Saba ES, Badran B, Sabra M, Kobeissy F, Bizri M. SARS-CoV-2 involvement in central nervous system tissue damage. Neural Regen Res. 2022 Jun; 17(6):1228-1239. PMID: 34782556.
      Citations:    
    71. Fakih W, Zeitoun R, AlZaim I, Eid AH, Kobeissy F, Abd-Elrahman KS, El-Yazbi AF. Early metabolic impairment as a contributor to neurodegenerative disease: Mechanisms and potential pharmacological intervention. Obesity (Silver Spring). 2022 May; 30(5):982-993. PMID: 35470973.
      Citations:    
    72. Habli Z, Kobeissy F, Khraiche ML. Advances in point-of-care platforms for traumatic brain injury: recent developments in diagnostics. Rev Neurosci. 2022 Apr 26; 33(3):327-345. PMID: 35170265.
      Citations:    
    73. Kobeissy F, Kobaisi A, Peng W, Barsa C, Goli M, Sibahi A, El Hayek S, Abdelhady S, Ali Haidar M, Sabra M, Orešic M, Logroscino G, Mondello S, Eid AH, Mechref Y. Glycomic and Glycoproteomic Techniques in Neurodegenerative Disorders and Neurotrauma: Towards Personalized Markers. Cells. 2022 Feb 08; 11(3). PMID: 35159390.
      Citations:    
    74. Kobeissy F, Mallah K, Zibara K, Dakroub F, Dalloul Z, Nasser M, Nasrallah L, Mallah Z, El-Achkar GA, Ramadan N, Mohamed W, Mondello S, Darwish H, Hamade E, Habib A. The effect of clopidogrel and aspirin on the severity of traumatic brain injury in a rat model. Neurochem Int. 2022 Mar; 154:105301. PMID: 35121011.
      Citations:    
    75. Nour-Eldine W, Sayyed K, Harhous Z, Dagher-Hamalian C, Mehanna S, Achkouti D, ElKazzaz H, Khnayzer RS, Kobeissy F, Khalil C, Abi-Gerges A. Gasoline fume inhalation induces apoptosis, inflammation, and favors Th2 polarization in C57BL/6 mice. J Appl Toxicol. 2022 Jul; 42(7):1178-1191. PMID: 35001415.
      Citations:    
    76. Haidar MA, Shakkour Z, Barsa C, Tabet M, Mekhjian S, Darwish H, Goli M, Shear D, Pandya JD, Mechref Y, El Khoury R, Wang K, Kobeissy F. Mitoquinone Helps Combat the Neurological, Cognitive, and Molecular Consequences of Open Head Traumatic Brain Injury at Chronic Time Point. Biomedicines. 2022 Jan 24; 10(2). PMID: 35203460.
      Citations:    
    77. Tabet M, El-Kurdi M, Haidar MA, Nasrallah L, Reslan MA, Shear D, Pandya JD, El-Yazbi AF, Sabra M, Mondello S, Mechref Y, Shaito A, Wang KK, El-Khoury R, Kobeissy F. Mitoquinone supplementation alleviates oxidative stress and pathologic outcomes following repetitive mild traumatic brain injury at a chronic time point. Exp Neurol. 2022 May; 351:113987. PMID: 35065054.
      Citations:    
    78. Slika H, Mansour H, Wehbe N, Nasser SA, Iratni R, Nasrallah G, Shaito A, Ghaddar T, Kobeissy F, Eid AH. Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms. Biomed Pharmacother. 2022 Feb; 146:112442. PMID: 35062053.
      Citations:    
    79. Watson CN, Begum G, Ashman E, Thorn D, Yakoub KM, Hariri MA, Nehme A, Mondello S, Kobeissy F, Belli A, Di Pietro V. Co-Expression Analysis of microRNAs and Proteins in Brain of Alzheimer's Disease Patients. Cells. 2022 Jan 04; 11(1). PMID: 35011725.
      Citations:    
    80. Haidar MA, Ibeh S, Shakkour Z, Reslan MA, Nwaiwu J, Moqidem YA, Sader G, Nickles RG, Babale I, Jaffa AA, Salama M, Shaito A, Kobeissy F. Crosstalk between Microglia and Neurons in Neurotrauma: An Overview of the Underlying Mechanisms. Curr Neuropharmacol. 2022; 20(11):2050-2065. PMID: 34856905.
      Citations:    
    81. Mondello S, Visalli C, Kobeissy F, Cacciani L, Cruciani F, D'Amato S, Di Napoli A, Giorgi Rossi P, Milli C, Petrelli A, Silvestri C, Cernigliaro A, Scondotto S. Exploring the evidence for the effectiveness of health interventions for COVID-19 targeting migrants: a systematic review protocol. BMJ Open. 2021 Dec 22; 11(12):e057985. PMID: 34937727.
      Citations:    
    82. Wang KK, Munoz Pareja JC, Mondello S, Diaz-Arrastia R, Wellington C, Kenney K, Puccio AM, Hutchison J, McKinnon N, Okonkwo DO, Yang Z, Kobeissy F, Tyndall JA, Büki A, Czeiter E, Pareja Zabala MC, Gandham N, Berman R. Blood-based traumatic brain injury biomarkers - Clinical utilities and regulatory pathways in the United States, Europe and Canada. Expert Rev Mol Diagn. 2021 Dec; 21(12):1303-1321. PMID: 34783274.
      Citations:    
    83. Jaffa AA, Jaffa MA, Moussa M, Ahmed IA, Karam M, Aldeen KS, Al Sayegh R, El-Achkar GA, Nasrallah L, Yehya Y, Habib A, Ziyadeh FN, Eid AH, Kobeissy FH, Jaffa AA. Modulation of Neuro-Inflammatory Signals in Microglia by Plasma Prekallikrein and Neuronal Cell Debris. Front Pharmacol. 2021; 12:743059. PMID: 34867349.
      Citations:    
    84. Kobeissy FH, Shakkour Z, Hayek SE, Mohamed W, Gold MS, Wang KKW. Correction to: Elevation of Pro-inflammatory and Anti-inflammatory Cytokines in Rat Serum after Acute Methamphetamine Treatment and Traumatic Brain Injury. J Mol Neurosci. 2022 Jan; 72(1):169. PMID: 34743263.
      Citations:    
    85. Bsat S, Halaoui A, Kobeissy F, Moussalem C, El Houshiemy MN, Kawtharani S, Omeis I. Acute ischemic stroke biomarkers: a new era with diagnostic promise? Acute Med Surg. 2021; 8(1):e696. PMID: 34745637.
      Citations:    
    86. Rose M, Cardon T, Aboulouard S, Hajjaji N, Kobeissy F, Duhamel M, Fournier I, Salzet M. Surfaceome Proteomic of Glioblastoma Revealed Potential Targets for Immunotherapy. Front Immunol. 2021; 12:746168. PMID: 34646273.
      Citations:    
    87. Kobeissy FH, Shakkour Z, Hayek SE, Mohamed W, Gold MS, Wang KKW. Elevation of Pro-inflammatory and Anti-inflammatory Cytokines in Rat Serum after Acute Methamphetamine Treatment and Traumatic Brain Injury. J Mol Neurosci. 2022 Jan; 72(1):158-168. PMID: 34542809.
      Citations:    
    88. Visalli C, Vinci SL, Mondello S, Kobeissy F, Salamone I, Coglitore A, Trimarchi R, Tessitore A, Impellizzeri P, Mormina E. Microvascular imaging ultrasound (MicroV) and power Doppler vascularization analysis in a pediatric population with early scrotal pain onset. Jpn J Radiol. 2022 Feb; 40(2):192-201. PMID: 34515926.
      Citations:    
    89. Abbasloo E, Abdollahi F, Saberi A, Esmaeili-Mahani S, Kaeidi A, Akhlaghinasab F, Sheibani V, Thomas TC, Kobeissy FH, Oryan S. Involvement of T-type calcium channels in the mechanism of low dose morphine-induced hyperalgesia in adult male rats. Neuropeptides. 2021 Dec; 90:102185. PMID: 34419803.
      Citations:    
    90. Saba ES, Karout M, Nasrallah L, Kobeissy F, Darwish H, Khoury SJ. Long-term cognitive deficits after traumatic brain injury associated with microglia activation. Clin Immunol. 2021 Sep; 230:108815. PMID: 34339843.
      Citations:    
    91. Mallah K, Zibara K, Kerbaj C, Eid A, Khoshman N, Ousseily Z, Kobeissy A, Cardon T, Cizkova D, Kobeissy F, Fournier I, Salzet M. Neurotrauma investigation through spatial omics guided by mass spectrometry imaging: Target identification and clinical applications. Mass Spectrom Rev. 2023 Jan; 42(1):189-205. PMID: 34323300.
      Citations:    
    92. Tarek M, Abdelzaher H, Kobeissy F, El-Fawal HAN, Salama MM, Abdelnaser A. Bioinformatics Analysis of Allele Frequencies and Expression Patterns of ACE2, TMPRSS2 and FURIN in Different Populations and Susceptibility to SARS-CoV-2. Genes (Basel). 2021 Jul 05; 12(7). PMID: 34356057.
      Citations:    
    93. Moussalem C, Massaad E, Minassian GB, Ftouni L, Bsat S, Houshiemy MNE, Alomari S, Sarieddine R, Kobeissy F, Omeis I. Meningioma genomics: a therapeutic challenge for clinicians. J Integr Neurosci. 2021 Jun 30; 20(2):463-469. PMID: 34258948.
      Citations:    
    94. Serag A, Shakkour Z, Halboup AM, Kobeissy F, Farag MA. Sweat metabolome and proteome: Recent trends in analytical advances and potential biological functions. J Proteomics. 2021 Aug 30; 246:104310. PMID: 34198014.
      Citations:    
    95. Mondello S, Kobeissy FH, Mechref Y, Zhao J, El Hayek S, Zibara K, Moresco M, Plazzi G, Cosentino FII, Ferri R. Searching for Novel Candidate Biomarkers of RLS in Blood by Proteomic Analysis. Nat Sci Sleep. 2021; 13:873-883. PMID: 34234594.
      Citations:    
    96. Peng W, Gutierrez Reyes CD, Gautam S, Yu A, Cho BG, Goli M, Donohoo K, Mondello S, Kobeissy F, Mechref Y. MS-based glycomics and glycoproteomics methods enabling isomeric characterization. Mass Spectrom Rev. 2023 Mar; 42(2):577-616. PMID: 34159615.
      Citations:    
    97. Jalloul D, Hajjar H, Asdikian R, Maawie M, Nasrallah L, Medlej Y, Darwich M, Karnib N, Lawand N, Abdel Rassoul R, Wang KKW, Kobeissy F, Darwish H, Obeid M. Potentiating Hemorrhage in a Periadolescent Rat Model of Closed-Head Traumatic Brain Injury Worsens Hyperexcitability but Not Behavioral Deficits. Int J Mol Sci. 2021 Jun 16; 22(12). PMID: 34208666.
      Citations:    
    98. Aboulouard S, Wisztorski M, Duhamel M, Saudemont P, Cardon T, Narducci F, Lemaire AS, Kobeissy F, Leblanc E, Fournier I, Salzet M. In-depth proteomics analysis of sentinel lymph nodes from individuals with endometrial cancer. Cell Rep Med. 2021 Jun 15; 2(6):100318. PMID: 34195683.
      Citations:    
    99. Al-Hajj S, Dhaini HR, Mondello S, Kaafarani H, Kobeissy F, DePalma RG. Beirut Ammonium Nitrate Blast: Analysis, Review, and Recommendations. Front Public Health. 2021; 9:657996. PMID: 34150702.
      Citations:    
    100. Ghossoub E, Geagea L, Kobeissy F, Talih F. Comparative effects of psychotropic medications on sleep architecture: a retrospective review of diagnostic polysomnography sleep parameters. Sleep Sci. 2021; 14(3):236-244. PMID: 35186202.
      Citations:    
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