Variant Surface Glycoproteins, Trypanosoma
"Variant Surface Glycoproteins, Trypanosoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amino acid sequence diversity expressed as antigenic variations. This continuous development of antigenically distinct variants in the course of infection ensures that some trypanosomes always survive the development of immune response to propagate the infection.
| Descriptor ID |
D014643
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| MeSH Number(s) |
D12.776.395.550.990 D12.776.543.550.990 D23.050.293.900 D23.050.301.900
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Variant Surface Glycoproteins, Trypanosoma".
Below are MeSH descriptors whose meaning is more specific than "Variant Surface Glycoproteins, Trypanosoma".
This graph shows the total number of publications written about "Variant Surface Glycoproteins, Trypanosoma" by people in this website by year, and whether "Variant Surface Glycoproteins, Trypanosoma" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Variant Surface Glycoproteins, Trypanosoma" by people in Profiles.
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Farrow AL, Rachakonda G, Gu L, Krendelchtchikova V, Nde PN, Pratap S, Lima MF, Villalta F, Matthews QL. Immunization with Hexon modified adenoviral vectors integrated with gp83 epitope provides protection against Trypanosoma cruzi infection. PLoS Negl Trop Dis. 2014 Aug; 8(8):e3089.
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Gruszynski AE, van Deursen FJ, Albareda MC, Best A, Chaudhary K, Cliffe LJ, del Rio L, Dunn JD, Ellis L, Evans KJ, Figueiredo JM, Malmquist NA, Omosun Y, Palenchar JB, Prickett S, Punkosdy GA, van Dooren G, Wang Q, Menon AK, Matthews KR, Bangs JD. Regulation of surface coat exchange by differentiating African trypanosomes. Mol Biochem Parasitol. 2006 Jun; 147(2):211-23.
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Di Noia JM, Buscaglia CA, De Marchi CR, Almeida IC, Frasch AC. A Trypanosoma cruzi small surface molecule provides the first immunological evidence that Chagas' disease is due to a single parasite lineage. J Exp Med. 2002 Feb 18; 195(4):401-13.
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Moody TN, Ochieng J, Villalta F. Novel mechanism that Trypanosoma cruzi uses to adhere to the extracellular matrix mediated by human galectin-3. FEBS Lett. 2000 Mar 31; 470(3):305-8.
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Das S, Traynor-Kaplan A, Kachintorn U, Aley SB, Gillin FD. GP49, an invariant GPI-anchored antigen of Giardia lamblia. Braz J Med Biol Res. 1994 Feb; 27(2):463-9.
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Lima MF, Villalta F. Trypanosoma cruzi trypomastigote clones differentially express a parasite cell adhesion molecule. Mol Biochem Parasitol. 1989 Mar 01; 33(2):159-70.
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Lima MF, Villalta F. Host-cell attachment by Trypanosoma cruzi: identification of an adhesion molecule. Biochem Biophys Res Commun. 1988 Aug 30; 155(1):256-62.