"Arrestin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 48-Kd protein of the outer segment of the retinal rods and a component of the phototransduction cascade. Arrestin quenches G-protein activation by binding to phosphorylated photolyzed rhodopsin. Arrestin causes experimental autoimmune uveitis when injected into laboratory animals.
| Descriptor ID |
D019393
|
| MeSH Number(s) |
D12.644.360.024.098.050 D12.776.157.057.005.050 D12.776.306.090.050 D12.776.476.024.104.050 D12.776.543.090.050 D23.050.301.280
|
| Concept/Terms |
Arrestin- Arrestin
- Retinal S-Antigen
- Retinal S Antigen
- S-Antigen, Retinal
- S Antigen, Retinal
|
Below are MeSH descriptors whose meaning is more general than "Arrestin".
Below are MeSH descriptors whose meaning is more specific than "Arrestin".
This graph shows the total number of publications written about "Arrestin" by people in this website by year, and whether "Arrestin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Arrestin" by people in Profiles.
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Nag S, Wang Q, Limbird LE, Mokha SS. Knockout of spinophilin, an endogenous antagonist of arrestin-dependent alpha2-adrenoceptor functions, enhances receptor-mediated antinociception yet does not eliminate sex-related differences. Behav Brain Res. 2009 Feb 11; 197(2):457-61.
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Groer CE, Tidgewell K, Moyer RA, Harding WW, Rothman RB, Prisinzano TE, Bohn LM. An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization. Mol Pharmacol. 2007 Feb; 71(2):549-57.
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Xue M, Vines CM, Buranda T, Cimino DF, Bennett TA, Prossnitz ER. N-formyl peptide receptors cluster in an active raft-associated state prior to phosphorylation. J Biol Chem. 2004 Oct 22; 279(43):45175-84.
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Zhang H, Cuenca N, Ivanova T, Church-Kopish J, Frederick JM, MacLeish PR, Baehr W. Identification and light-dependent translocation of a cone-specific antigen, cone arrestin, recognized by monoclonal antibody 7G6. Invest Ophthalmol Vis Sci. 2003 Jul; 44(7):2858-67.
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Vines CM, Xue M, Maestas DC, Cimino DF, Prossnitz ER. Regulation of N-formyl peptide-mediated degranulation by receptor phosphorylation. J Immunol. 2002 Dec 15; 169(12):6760-6.