Glucose Transporter Type 1

"Glucose Transporter Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A ubiquitously expressed glucose transporter that is important for constitutive, basal GLUCOSE transport. It is predominately expressed in ENDOTHELIAL CELLS and ERYTHROCYTES at the BLOOD-BRAIN BARRIER and is responsible for GLUCOSE entry into the BRAIN.

Descriptor ID	D051272
MeSH Number(s)	D12.776.157.530.500.500.500 D12.776.157.530.937.563.500 D12.776.543.585.500.500.500 D12.776.543.585.937.625.500
Concept/Terms	Glucose Transporter Type 1 Glucose Transporter Type 1 GLUT-1 Protein GLUT 1 Protein Solute Carrier Family 2, Facilitated Glucose Transporter, Member 1 Protein SLC2A1 Protein GLUT1 Protein Erythrocyte Glucose Transporter Glucose Transporter, Erythrocyte

Below are MeSH descriptors whose meaning is more general than "Glucose Transporter Type 1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Monosaccharide Transport Proteins [D12.776.157.530.500]
Glucose Transport Proteins, Facilitative [D12.776.157.530.500.500]
Glucose Transporter Type 1 [D12.776.157.530.500.500.500]
Solute Carrier Proteins [D12.776.157.530.937]
Glucose Transport Proteins, Facilitative [D12.776.157.530.937.563]
Glucose Transporter Type 1 [D12.776.157.530.937.563.500]
Membrane Proteins [D12.776.543]
Membrane Transport Proteins [D12.776.543.585]
Monosaccharide Transport Proteins [D12.776.543.585.500]
Glucose Transport Proteins, Facilitative [D12.776.543.585.500.500]
Glucose Transporter Type 1 [D12.776.543.585.500.500.500]
Solute Carrier Proteins [D12.776.543.585.937]
Glucose Transport Proteins, Facilitative [D12.776.543.585.937.625]
Glucose Transporter Type 1 [D12.776.543.585.937.625.500]

Below are MeSH descriptors whose meaning is related to "Glucose Transporter Type 1".

Below are MeSH descriptors whose meaning is more specific than "Glucose Transporter Type 1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Glucose Transporter Type 1" by people in this website by year, and whether "Glucose Transporter Type 1" was a major or minor topic of these publications.

Bar chart showing 19 publications over 11 distinct years, with a maximum of 5 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	0	1	1
2006	1	0	1
2009	1	2	3
2010	0	1	1
2011	0	2	2
2016	1	1	2
2017	0	1	1
2019	1	0	1
2020	3	2	5
2022	0	1	1
2024	1	0	1

Below are the most recent publications written about "Glucose Transporter Type 1" by people in Profiles.

Nakayama Y, Kobayashi S, Masihuddin A, Abdali SA, Seneviratne AMPB, Ishii S, Iida J, Liang Q, Yoshioka J. Systemic Deletion of ARRDC4 Improves Cardiac Reserve and Exercise Capacity in Diabetes. Circ Res. 2024 Jul 19; 135(3):416-433.

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Nakayama Y, Mukai N, Kreitzer G, Patwari P, Yoshioka J. Interaction of ARRDC4 With GLUT1 Mediates Metabolic Stress in the Ischemic Heart. Circ Res. 2022 09 02; 131(6):510-527.

View in: PubMed
Hendrix RD, Ou Y, Davis JE, Odle AK, Groves TR, Allen AR, Childs GV, Barger SW. Alzheimer amyloid-?- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood. Neurobiol Aging. 2021 01; 97:73-88.

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Dai W, Xu Y, Mo S, Li Q, Yu J, Wang R, Ma Y, Ni Y, Xiang W, Han L, Zhang L, Cai S, Qin J, Chen WL, Jia W, Cai G. GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies. Signal Transduct Target Ther. 2020 09 02; 5(1):177.

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Tilekar K, Upadhyay N, Schweipert M, Hess JD, Macias LH, Mrowka P, Meyer-Almes FJ, Aguilera RJ, Iancu CV, Choe JY, Ramaa CS. Permuted 2,4-thiazolidinedione (TZD) analogs as GLUT inhibitors and their in-vitro evaluation in leukemic cells. Eur J Pharm Sci. 2020 Nov 01; 154:105512.

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Tilekar K, Upadhyay N, Hess JD, Macias LH, Mrowka P, Aguilera RJ, Meyer-Almes FJ, Iancu CV, Choe JY, Ramaa CS. Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential. Eur J Med Chem. 2020 Sep 15; 202:112603.

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Upadhyay N, Tilekar K, J?nsch N, Schweipert M, Hess JD, Henze Macias L, Mrowka P, Aguilera RJ, Choe JY, Meyer-Almes FJ, Ramaa CS. Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: in-silico studies, synthesis, and biological evaluation. Bioorg Chem. 2020 07; 100:103934.

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Chen LY, Phelix CF. Extracellular gating of glucose transport through GLUT 1. Biochem Biophys Res Commun. 2019 04 09; 511(3):573-578.

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Pereira PMR, Berisha N, Bhupathiraju NVSDK, Fernandes R, Tom? JPC, Drain CM. Cancer cell spheroids are a better screen for the photodynamic efficiency of glycosylated photosensitizers. PLoS One. 2017; 12(5):e0177737.

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Fernandez AM, Hernandez-Garz?n E, Perez-Domper P, Perez-Alvarez A, Mederos S, Matsui T, Santi A, Trueba-Saiz A, Garc?a-Guerra L, Pose-Utrilla J, Fielitz J, Olson EN, Fernandez de la Rosa R, Garcia Garcia L, Pozo MA, Iglesias T, Araque A, Soya H, Perea G, Martin ED, Torres Aleman I. Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I. Diabetes. 2017 Jan; 66(1):64-74.

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