Thioredoxins

"Thioredoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.

Descriptor ID	D013879
MeSH Number(s)	D12.776.915
Concept/Terms	Thioredoxins Thioredoxins Thioredoxin Thioredoxin 2 Thioredoxin 2 Thioredoxin-2 Thioredoxin 1 Thioredoxin 1 Thioredoxin-1

Below are MeSH descriptors whose meaning is more general than "Thioredoxins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Thioredoxins [D12.776.915]

Below are MeSH descriptors whose meaning is related to "Thioredoxins".

Below are MeSH descriptors whose meaning is more specific than "Thioredoxins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Thioredoxins" by people in this website by year, and whether "Thioredoxins" was a major or minor topic of these publications.

Bar chart showing 26 publications over 18 distinct years, with a maximum of 3 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1997	1	0	1
1998	1	0	1
1999	2	0	2
2000	2	0	2
2001	2	0	2
2004	2	1	3
2005	1	0	1
2006	1	1	2
2007	1	0	1
2008	1	0	1
2009	1	0	1
2010	0	1	1
2016	0	1	1
2017	1	0	1
2018	2	0	2
2019	2	0	2
2021	1	0	1

Below are the most recent publications written about "Thioredoxins" by people in Profiles.

Shrihari S, May HC, Yu JJ, Papp SB, Chambers JP, Guentzel MN, Arulanandam BP. Thioredoxin-mediated alteration of protein content and cytotoxicity of Acinetobacter baumannii outer membrane vesicles. Exp Biol Med (Maywood). 2022 02; 247(3):282-288.

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May HC, Yu JJ, Zhang H, Wang Y, Cap AP, Chambers JP, Guentzel MN, Arulanandam BP. Thioredoxin-A is a virulence factor and mediator of the type IV pilus system in Acinetobacter baumannii. PLoS One. 2019; 14(7):e0218505.

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Gong T, Hashimoto AC, Sasuclark AR, Khadka VS, Gurary A, Pitts MW. Selenoprotein M Promotes Hypothalamic Leptin Signaling and Thioredoxin Antioxidant Activity. Antioxid Redox Signal. 2021 10 01; 35(10):775-787.

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Ketter PM, Yu JJ, Guentzel MN, May HC, Gupta R, Eppinger M, Klose KE, Seshu J, Chambers JP, Cap AP, Arulanandam BP. Acinetobacter baumannii Gastrointestinal Colonization Is Facilitated by Secretory IgA Which Is Reductively Dissociated by Bacterial Thioredoxin A. mBio. 2018 07 10; 9(4).

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Wen Y, Liu YR, Tang TT, Pan MM, Xu SC, Ma KL, Lv LL, Liu H, Liu BC. mROS-TXNIP axis activates NLRP3 inflammasome to mediate renal injury during ischemic AKI. Int J Biochem Cell Biol. 2018 05; 98:43-53.

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Ainsworth S, Ketter PM, Yu JJ, Grimm RC, May HC, Cap AP, Chambers JP, Guentzel MN, Arulanandam BP. Vaccination with a live attenuated Acinetobacter baumannii deficient in thioredoxin provides protection against systemic Acinetobacter infection. Vaccine. 2017 06 08; 35(26):3387-3394.

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Pad?n-Irizarry V, Col?n-Lorenzo EE, Vega-Rodr?guez J, Castro Mdel R, Gonz?lez-M?ndez R, Ayala-Pe?a S, Serrano AE. Glutathione-deficient Plasmodium berghei parasites exhibit growth delay and nuclear DNA damage. Free Radic Biol Med. 2016 06; 95:43-54.

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Kraft-Terry S, Gerena Y, Wojna V, Plaud-Valentin M, Rodriguez Y, Ciborowski P, Mayo R, Skolasky R, Gendelman HE, Mel?ndez LM. Proteomic analyses of monocytes obtained from Hispanic women with HIV-associated dementia show depressed antioxidants. Proteomics Clin Appl. 2010 Sep; 4(8-9):706-14.

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Yang J, Tasayco ML, Polenova T. Dynamics of reassembled thioredoxin studied by magic angle spinning NMR: snapshots from different time scales. J Am Chem Soc. 2009 Sep 30; 131(38):13690-702.

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Yang J, Tasayco ML, Polenova T. Magic angle spinning NMR experiments for structural studies of differentially enriched protein interfaces and protein assemblies. J Am Chem Soc. 2008 Apr 30; 130(17):5798-807.

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