"Iron-Regulatory Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that regulate cellular and organismal iron homeostasis. They play an important biological role by maintaining iron levels that are adequate for metabolic need, but below the toxicity threshold.
| Descriptor ID |
D035925
|
| MeSH Number(s) |
D12.776.494
|
| Concept/Terms |
Iron-Regulatory Proteins- Iron-Regulatory Proteins
- Iron Regulatory Proteins
- Iron-Regulatory Protein
- Iron Regulatory Protein
- Iron Regulatory Factor
- Regulatory Factor, Iron
- Iron-Response Proteins
- Iron Response Proteins
Iron-Responsive Element Binding Proteins- Iron-Responsive Element Binding Proteins
- Iron Responsive Element Binding Proteins
- IRE-BP
- Iron-Responsive Elements-Binding Protein
- Iron Responsive Elements Binding Protein
- IRE-Binding Protein
- IRE Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Iron-Regulatory Proteins".
Below are MeSH descriptors whose meaning is more specific than "Iron-Regulatory Proteins".
This graph shows the total number of publications written about "Iron-Regulatory Proteins" by people in this website by year, and whether "Iron-Regulatory Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Iron-Regulatory Proteins" by people in Profiles.
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Ma J, Haldar S, Khan MA, Sharma SD, Merrick WC, Theil EC, Goss DJ. Fe2+ binds iron responsive element-RNA, selectively changing protein-binding affinities and regulating mRNA repression and activation. Proc Natl Acad Sci U S A. 2012 May 29; 109(22):8417-22.
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Hodges M, Yikilmaz E, Patterson G, Kasvosve I, Rouault TA, Gordeuk VR, Loyevsky M. An iron regulatory-like protein expressed in Plasmodium falciparum displays aconitase activity. Mol Biochem Parasitol. 2005 Sep; 143(1):29-38.
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Loyevsky M, Mompoint F, Yikilmaz E, Altschul SF, Madden T, Wootton JC, Kurantsin-Mills J, Kassim OO, Gordeuk VR, Rouault TA. Expression of a recombinant IRP-like Plasmodium falciparum protein that specifically binds putative plasmodial IREs. Mol Biochem Parasitol. 2003 Feb; 126(2):231-8.
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Smith MA, Wehr K, Harris PL, Siedlak SL, Connor JR, Perry G. Abnormal localization of iron regulatory protein in Alzheimer's disease. Brain Res. 1998 Mar 30; 788(1-2):232-6.