Interferon-gamma

"Interferon-gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.

Descriptor ID	D007371
MeSH Number(s)	D12.644.276.374.440.893 D12.644.276.374.480.615.350 D12.776.467.374.440.893 D12.776.467.374.480.615.350 D23.529.374.440.893 D23.529.374.480.615.350
Concept/Terms	Interferon-gamma Interferon-gamma gamma-Interferon Interferon, Immune Immune Interferon Type II Interferon Interferon, Type II Interferon Type II Interferon, gamma

Below are MeSH descriptors whose meaning is more general than "Interferon-gamma".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interferons [D12.644.276.374.440]
Interferon-gamma [D12.644.276.374.440.893]
Lymphokines [D12.644.276.374.480]
Macrophage-Activating Factors [D12.644.276.374.480.615]
Interferon-gamma [D12.644.276.374.480.615.350]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interferons [D12.776.467.374.440]
Interferon-gamma [D12.776.467.374.440.893]
Lymphokines [D12.776.467.374.480]
Macrophage-Activating Factors [D12.776.467.374.480.615]
Interferon-gamma [D12.776.467.374.480.615.350]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interferons [D23.529.374.440]
Interferon-gamma [D23.529.374.440.893]
Lymphokines [D23.529.374.480]
Macrophage-Activating Factors [D23.529.374.480.615]
Interferon-gamma [D23.529.374.480.615.350]

Below are MeSH descriptors whose meaning is related to "Interferon-gamma".

Below are MeSH descriptors whose meaning is more specific than "Interferon-gamma".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interferon-gamma" by people in this website by year, and whether "Interferon-gamma" was a major or minor topic of these publications.

Bar chart showing 162 publications over 28 distinct years, with a maximum of 13 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1997	1	1	2
1998	1	6	7
1999	0	3	3
2000	0	5	5
2001	0	4	4
2002	5	4	9
2003	2	4	6
2004	0	5	5
2005	1	7	8
2006	3	3	6
2007	5	8	13
2008	5	7	12
2009	1	9	10
2010	3	5	8
2011	4	5	9
2012	1	3	4
2013	1	8	9
2014	0	1	1
2015	1	2	3
2016	1	8	9
2017	2	3	5
2018	4	3	7
2019	1	1	2
2020	0	2	2
2021	2	5	7
2022	1	0	1
2023	1	2	3

Below are the most recent publications written about "Interferon-gamma" by people in Profiles.

Silva BJA, Krogstad PA, Teles RMB, Andrade PR, Rajfer J, Ferrini MG, Yang OO, Bloom BR, Modlin RL. IFN-?-mediated control of SARS-CoV-2 infection through nitric oxide. Front Immunol. 2023; 14:1284148.

View in: PubMed
Kojima K, Chambers JK, Nakashima K, Uchida K. Pro-inflammatory cytokine expression and the STAT1/3 pathway in canine chronic enteropathy and intestinal T-cell lymphoma. Vet Pathol. 2024 May; 61(3):382-392.

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Roca Suarez AA, Planel S, Grand X, Couturier C, Tran T, Porcheray F, Becker J, Reynier F, Delgado A, Cascales E, Peyrot L, Tamellini A, Saliou A, Elie C, Baum C, Vuong BQ, Testoni B, Roques P, Zoulim F, Hasan U, Chemin I. Interspecies comparison of the early transcriptomic changes associated with hepatitis B virus exposure in human and macaque immune cell populations. Front Cell Infect Microbiol. 2023; 13:1248782.

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Zhou B, Basu J, Kazmi HR, Chitrala KN, Mo X, Preston-Alp S, Cai KQ, Kappes D, Zaidi MR. Interferon-gamma signaling promotes melanoma progression and metastasis. Oncogene. 2023 01; 42(5):351-363.

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Diorio C, Shraim R, Vella LA, Giles JR, Baxter AE, Oldridge DA, Canna SW, Henrickson SE, McNerney KO, Balamuth F, Burudpakdee C, Lee J, Leng T, Farrel A, Lambert MP, Sullivan KE, Wherry EJ, Teachey DT, Bassiri H, Behrens EM. Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction. Nat Commun. 2021 12 10; 12(1):7222.

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Luo Y, Xue Y, Lin Q, Mao L, Tang G, Song H, Liu W, Wu S, Liu W, Zhou Y, Xu L, Xiong Z, Wang T, Yuan X, Gan Y, Sun Z, Wang F. Diagnostic Model for Discrimination Between Tuberculous Meningitis and Bacterial Meningitis. Front Immunol. 2021; 12:731876.

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Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B. Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells. Nat Immunol. 2022 01; 23(1):62-74.

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Zhang R, Jones MM, Parker D, Dornsife RE, Wymer N, Onyenwoke RU, Sivaraman V. Acute vaping exacerbates microbial pneumonia due to calcium (Ca2+) dysregulation. PLoS One. 2021; 16(8):e0256166.

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Zuo Z, Zou Y, Li Q, Guo Y, Zhang T, Wu J, He C, Eko FO. Intranasal immunization with inactivated chlamydial elementary bodies formulated in VCG-chitosan nanoparticles induces robust immunity against intranasal Chlamydia psittaci challenge. Sci Rep. 2021 05 17; 11(1):10389.

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Liu D, Vadgama J, Wu Y. Basal-like breast cancer with low TGF? and high TNFa pathway activity is rich in activated memory CD4 T cells and has a good prognosis. Int J Biol Sci. 2021; 17(3):670-682.

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